2,3,4,6-tetra-O-acetyl-α-D-galactopyranosyl diphenyl phosphate

Base Information

• Chemical Name: 2,3,4,6-tetra-O-acetyl-α-D-galactopyranosyl diphenyl phosphate
• CAS No.: 110808-92-9
• Molecular Formula: C₂₆H₂₉O₁₃P
• Molecular Weight: 580.482
• Mol file: 110808-92-9.mol

Synonyms:2,3,4,6-tetra-O-acetyl-α-D-galactopyranosyl diphenyl phosphate

Chemical Property of 2,3,4,6-tetra-O-acetyl-α-D-galactopyranosyl diphenyl phosphate

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

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Technology Process of 2,3,4,6-tetra-O-acetyl-α-D-galactopyranosyl diphenyl phosphate

There total 6 articles about 2,3,4,6-tetra-O-acetyl-α-D-galactopyranosyl diphenyl phosphate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 78.0%

2,3,4,6-tetra-O-acetyl-α/β-D-galactopyranose (3947-62-4,6207-76-7,10343-06-3,19235-21-3,22554-70-7,22860-22-6,57884-82-9,62057-79-8,70191-05-8,109525-54-4,140147-37-1,47339-09-3) + chlorophosphoric acid diphenyl ester (2524-64-3) → 2,3,4,6-tetra-O-acetyl-α-D-galactopyranosyl diphenyl phosphate (110808-92-9)

Guidance literature:

With dmap; In dichloromethane; 1) -10 to 0 deg C, 2 h, 2) 4 deg C, 1 h;

DOI:10.1016/0008-6215(92)80015-S

Reference yield: 60.0%

2,3,4,6-tetra-O-acetyl-α-D-galactopyranosyl nitrate (13225-04-2) + cesium diphenyl phosphate → 2,3,4,6-tetra-O-acetyl-α-D-galactopyranosyl diphenyl phosphate (110808-92-9)

Guidance literature:

With 18-crown-6 ether; In N,N-dimethyl-formamide; at 50 ℃; for 12h;

DOI:10.1016/S0040-4039(99)00698-X

Reference yield: 50.0%

2,3,4,6-tetra-O-acetyl-α/β-D-galactopyranose (3947-62-4,6207-76-7,10343-06-3,19235-21-3,22554-70-7,22860-22-6,57884-82-9,62057-79-8,70191-05-8,109525-54-4,140147-37-1,47339-09-3) + chlorophosphoric acid diphenyl ester (2524-64-3) → 2,3,4,6-tetra-O-acetyl-β-D-galactopyranosyl diphenyl phosphate (141607-30-9) + 2,3,4,6-tetra-O-acetyl-α-D-galactopyranosyl diphenyl phosphate (110808-92-9)

Guidance literature:

With dmap; In dichloromethane; at -20 - -10 ℃; for 1h;

DOI:10.1016/0008-6215(92)80015-S

upstream raw materials:

2,3,4,6-tetra-O-acetyl-α/β-D-galactopyranose

chlorophosphoric acid diphenyl ester

2,3,4,6-tetra-O-acetyl-α-D-galactopyranosyl nitrate

1-bromo-1-deoxy-2,3,4,6-tetra-O-acetyl-a-D-galactopyranoside

Downstream raw materials:

(2R,3S,4S,5R,6R)-2-(acetoxymethyl)-6-azidotetrahydro-2H-pyran-3,4,5-triyl triacetate