ethyl 3-[7-(5-{3-chloro-4-[(1-methylethyl)oxy]phenyl}-1,2,4-oxadiazol-3-yl)-1H-pyrrolo[2,3-c]pyridin-4-yl]propanoate

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Chemical Name:ethyl 3-[7-(5-{3-chloro-4-[(1-methylethyl)oxy]phenyl}-1,2,4-oxadiazol-3-yl)-1H-pyrrolo[2,3-c]pyridin-4-yl]propanoate
CAS No.:1258960-22-3
Molecular Formula:C₂₃H₂₃ClN₄O₄
Molecular Weight:454.913
Hs Code.:

Synonyms:ethyl 3-[7-(5-{3-chloro-4-[(1-methylethyl)oxy]phenyl}-1,2,4-oxadiazol-3-yl)-1H-pyrrolo[2,3-c]pyridin-4-yl]propanoate

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Chemical Property of ethyl 3-[7-(5-{3-chloro-4-[(1-methylethyl)oxy]phenyl}-1,2,4-oxadiazol-3-yl)-1H-pyrrolo[2,3-c]pyridin-4-yl]propanoate

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Technology Process of ethyl 3-[7-(5-{3-chloro-4-[(1-methylethyl)oxy]phenyl}-1,2,4-oxadiazol-3-yl)-1H-pyrrolo[2,3-c]pyridin-4-yl]propanoate

There total 1 articles about ethyl 3-[7-(5-{3-chloro-4-[(1-methylethyl)oxy]phenyl}-1,2,4-oxadiazol-3-yl)-1H-pyrrolo[2,3-c]pyridin-4-yl]propanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1259032-17-1,1258960-28-9
ethyl 3-{7-[(Z)-(hydroxyimino)(amino)methyl]-1-[(4-methylphenyl)sulfonyl]-1H-pyrrolo[2,3-c]pyridin-4-yl}propanoate

: 213598-07-3
3-chloro-4-isopropoxy-benzoic acid

: 1258960-22-3
ethyl 3-[7-(5-{3-chloro-4-[(1-methylethyl)oxy]phenyl}-1,2,4-oxadiazol-3-yl)-1H-pyrrolo[2,3-c]pyridin-4-yl]propanoate

Guidance literature:: 3-chloro-4-isopropoxy-benzoic acid; With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In tetrahydrofuran; at 20 ℃; for 1h; Inert atmosphere;

ethyl 3-{7-[(Z)-(hydroxyimino)(amino)methyl]-1-[(4-methylphenyl)sulfonyl]-1H-pyrrolo[2,3-c]pyridin-4-yl}propanoate; In tetrahydrofuran; at 20 ℃; for 1h;

With tetrabutyl ammonium fluoride; In tetrahydrofuran; at 120 ℃; for 1h; Microwave irradiation;

Reference yield:

: 1258960-22-3
ethyl 3-[7-(5-{3-chloro-4-[(1-methylethyl)oxy]phenyl}-1,2,4-oxadiazol-3-yl)-1H-pyrrolo[2,3-c]pyridin-4-yl]propanoate

: 1258959-56-6
3-[7-(5-{3-chloro-4-[(1-methylethyl)oxy]phenyl}-1,2,4-oxadiazol-3-yl)-1H-pyrrolo[2,3-c]pyridin-4-yl]propanoic acid

Guidance literature:: ethyl 3-[7-(5-{3-chloro-4-[(1-methylethyl)oxy]phenyl}-1,2,4-oxadiazol-3-yl)-1H-pyrrolo[2,3-c]pyridin-4-yl]propanoate; With water; sodium hydroxide; In tetrahydrofuran; methanol; at 70 ℃; for 1h;

With hydrogenchloride; In tetrahydrofuran; methanol; water;