Technology Process of 2-Methyltridecanoic acid methyl ester
There total 3 articles about 2-Methyltridecanoic acid methyl ester which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
methyl tridecanoate;
With
lithium diisopropyl amide;
In
tetrahydrofuran;
at -78 - -20 ℃;
for 2.75h;
methyl iodide;
With
1,3-dimethyl-3,4,5,6-tetrahydro-2(1H)-pyrimidinone;
In
tetrahydrofuran;
at -78 - 20 ℃;
for 4.5h;
DOI:10.1002/cbdv.201600020
- Guidance literature:
-
trimethyl 2-phosphonopropionate;
With
sodium hydride;
In
tetrahydrofuran; mineral oil;
at 0 - 40 ℃;
undecylaldehyde;
In
tetrahydrofuran; mineral oil;
for 24h;
Reflux;
With
platinum(IV) oxide; hydrogen;
In
methanol;
DOI:10.1002/cbdv.201000190
- Guidance literature:
-
Multi-step reaction with 2 steps
1.1: dmap; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride / 0 - 20 °C / Inert atmosphere
2.1: lithium diisopropyl amide / tetrahydrofuran / 2.75 h / -78 - -20 °C
2.2: 4.5 h / -78 - 20 °C
With
dmap; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; lithium diisopropyl amide;
In
tetrahydrofuran;
DOI:10.1002/cbdv.201600020
