Carbamic acid, (2-fluorocyclopropyl)-, 1,1-dimethylethyl ester, (1S-cis)- (9CI)

Base Information

Chemical Name:Carbamic acid, (2-fluorocyclopropyl)-, 1,1-dimethylethyl ester, (1S-cis)- (9CI)
CAS No.:127199-15-9
Molecular Formula:C₈H₁₄FNO₂
Molecular Weight:175.203
Hs Code.:
Mol file:127199-15-9.mol

Synonyms:Carbamicacid, (2-fluorocyclopropyl)-, 1,1-dimethylethyl ester, (1S-cis)- (9CI)

Suppliers and Price of Carbamic acid, (2-fluorocyclopropyl)-, 1,1-dimethylethyl ester, (1S-cis)- (9CI)

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 3 raw suppliers

Chemical Property of Carbamic acid, (2-fluorocyclopropyl)-, 1,1-dimethylethyl ester, (1S-cis)- (9CI)

Chemical Property:

PSA：38.33000
LogP:2.01240

Purity/Quality:: 98% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of Carbamic acid, (2-fluorocyclopropyl)-, 1,1-dimethylethyl ester, (1S-cis)- (9CI)

There total 5 articles about Carbamic acid, (2-fluorocyclopropyl)-, 1,1-dimethylethyl ester, (1S-cis)- (9CI) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 78.0%

: 24424-99-5
di-tert-butyl dicarbonate

: 114152-95-3,114152-96-4,141042-20-8,141042-21-9,143062-71-9,143062-74-2,143062-85-5
(1R*,2S*)-2-fluorocyclopropylamine hydrochloride

: 105919-35-5,127199-15-9,127199-16-0,142977-47-7,143022-91-7,143840-33-9,146726-40-1,167073-09-8
tert-butyl dl-N-(cis-2-fluorocyclopropyl)carbamate

Guidance literature:: With triethylamine; In dichloromethane; at 0 ℃; for 2h;
DOI:10.1016/S0040-4020(01)89665-4

Reference yield: 28.0%

: 24424-99-5
di-tert-butyl dicarbonate

: 114152-95-3,114152-96-4,141042-20-8,141042-21-9,143062-71-9,143062-74-2,143062-85-5
(1R*,2R*)-2-fluorocyclopropylamine hydrochloride

: 105919-35-5,127199-15-9,127199-16-0,142977-47-7,143022-91-7,143840-33-9,146726-40-1,167073-09-8
tert-butyl dl-N-(trans-2-fluorocyclopropyl)carbamate

Guidance literature:: With triethylamine; In dichloromethane; at 0 ℃; for 2h;
DOI:10.1016/S0040-4020(01)89665-4

Reference yield: 18.0%

: 1493-01-2
fluorodiiodomethane

: 7150-72-3
t-butyl N-vinylcarbamate

: 105919-35-5,127199-15-9,127199-16-0,142977-47-7,143022-91-7,143840-33-9,146726-40-1,167073-09-8
tert-butyl dl-N-(trans-2-fluorocyclopropyl)carbamate

: 105919-35-5,127199-15-9,127199-16-0,142977-47-7,143022-91-7,143840-33-9,146726-40-1,167073-09-8
tert-butyl dl-N-(cis-2-fluorocyclopropyl)carbamate

Guidance literature:: With 1,2-dimethoxyethane; 4 A molecular sieve; diethylzinc; In hexane; dichloromethane; at 0 ℃; for 0.5h;
DOI:10.1016/S0040-4020(01)89665-4