(4S)-4-Benzyl-L-glutamic acid

Base Information

Chemical Name:(4S)-4-Benzyl-L-glutamic acid
CAS No.:129446-71-5
Molecular Formula:C₁₂H₁₅NO₄
Molecular Weight:237.255
Hs Code.:
DSSTox Substance ID:DTXSID20428803
Nikkaji Number:J651.354I
Wikidata:Q82241635
ChEMBL ID:CHEMBL424016
Mol file:129446-71-5.mol

Synonyms:129446-71-5;(4S)-4-Benzyl-L-glutamic acid;(2s,4s)-2-amino-4-benzylpentanedioic acid;(2S,4S)-2-amino-4-benzyl-pentanedioic Acid;CHEMBL424016;SCHEMBL2265548;DTXSID20428803;MFCD07784027;AKOS022180494;(2S,4S)-2-Amino-4-benzylglutaric acid;(2s,4s)-2-amino-4-benzylpentanedioicacid

Suppliers and Price of (4S)-4-Benzyl-L-glutamic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
(4S)-4-Benzyl-L-glutamicAcid
100mg
$ 240.00

Crysdot
(2S,4S)-2-Amino-4-benzylpentanedioicacid 97%
1g
$ 606.00

Crysdot
(2S,4S)-2-Amino-4-benzylpentanedioicacid 97%
5g
$ 1823.00

American Custom Chemicals Corporation
(2S,4S)-2-AMINO-4-BENZYL-PENTANEDIOIC ACID 95.00%
5G
$ 2683.80

American Custom Chemicals Corporation
(2S,4S)-2-AMINO-4-BENZYL-PENTANEDIOIC ACID 95.00%
500MG
$ 1067.22

Alichem
(2S,4S)-2-Amino-4-benzylpentanedioicacid
5g
$ 1577.18

Total 16 raw suppliers

Chemical Property of (4S)-4-Benzyl-L-glutamic acid

Chemical Property:

Vapor Pressure:9.12E-09mmHg at 25°C
Refractive Index:1.584
Boiling Point:446.8°Cat760mmHg
Flash Point:224°C
PSA：100.62000
Density:1.303g/cm³
LogP:1.43220
Storage Temp.:2-8°C
XLogP3:-1.6
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:6
Exact Mass:237.10010796
Heavy Atom Count:17
Complexity:274

Purity/Quality:

97% ^*data from raw suppliers

(4S)-4-Benzyl-L-glutamicAcid ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C(C=C1)CC(CC(C(=O)O)N)C(=O)O
Isomeric SMILES:C1=CC=C(C=C1)C[C@@H](C[C@@H](C(=O)O)N)C(=O)O

Technology Process of (4S)-4-Benzyl-L-glutamic acid

There total 11 articles about (4S)-4-Benzyl-L-glutamic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 100-52-7
benzaldehyde

: 129446-71-5,402821-16-3
(2S,4S)-2-Amino-4-benzyl-pentanedioic acid

Guidance literature:: Multi-step reaction with 4 steps

1: 1.) lithium hexamethyldisilazide, 2.) BF₃*Et₂O / 1.) THF, -78 deg C, 1 h, 2.) THF, -78 deg C, 1 h

2: MsCl, Et₃N / CH₂Cl₂ / 48 h / Ambient temperature

3: H₂ / PtO₂ / ethyl acetate / 4 h / 760 Torr / Ambient temperature

4: 6 N HCl / Heating

With hydrogenchloride; boron trifluoride diethyl etherate; hydrogen; methanesulfonyl chloride; triethylamine; lithium hexamethyldisilazane; platinum(IV) oxide; In dichloromethane; ethyl acetate;
DOI:10.1016/S0960-894X(98)00091-2

Reference yield:

: 144978-35-8,144978-12-1,251924-83-1
(S)-ethyl N-tert-butoxycarbonylpyroglutamate

: 129446-71-5,402821-16-3
(2S,4S)-2-Amino-4-benzyl-pentanedioic acid

Guidance literature:: Multi-step reaction with 4 steps

1: 1.) lithium hexamethyldisilazide, 2.) BF₃*Et₂O / 1.) THF, -78 deg C, 1 h, 2.) THF, -78 deg C, 1 h

2: MsCl, Et₃N / CH₂Cl₂ / 48 h / Ambient temperature

3: H₂ / PtO₂ / ethyl acetate / 4 h / 760 Torr / Ambient temperature

4: 6 N HCl / Heating

With hydrogenchloride; boron trifluoride diethyl etherate; hydrogen; methanesulfonyl chloride; triethylamine; lithium hexamethyldisilazane; platinum(IV) oxide; In dichloromethane; ethyl acetate;
DOI:10.1016/S0960-894X(98)00091-2

Reference yield:

: (S)-4-(Hydroxy-phenyl-methyl)-5-oxo-pyrrolidine-1,2-dicarboxylic acid 1-tert-butyl ester 2-ethyl ester

: 129446-71-5,402821-16-3
(2S,4S)-2-Amino-4-benzyl-pentanedioic acid

Guidance literature:: Multi-step reaction with 3 steps

1: MsCl, Et₃N / CH₂Cl₂ / 48 h / Ambient temperature

2: H₂ / PtO₂ / ethyl acetate / 4 h / 760 Torr / Ambient temperature

3: 6 N HCl / Heating

With hydrogenchloride; hydrogen; methanesulfonyl chloride; triethylamine; platinum(IV) oxide; In dichloromethane; ethyl acetate;
DOI:10.1016/S0960-894X(98)00091-2