Ethyl 6-(piperazin-1-yl)nicotinate

Base Information

Chemical Name:Ethyl 6-(piperazin-1-yl)nicotinate
CAS No.:132521-78-9
Molecular Formula:C12H17N3O2
Molecular Weight:235.286
Hs Code.:2933599090
DSSTox Substance ID:DTXSID90566600
Wikidata:Q82452284
Mol file:132521-78-9.mol

Synonyms:132521-78-9;Ethyl 6-(piperazin-1-yl)nicotinate;ethyl 6-piperazin-1-ylnicotinate;ethyl 6-(piperazin-1-yl)pyridine-3-carboxylate;ethyl 6-piperazin-1-ylpyridine-3-carboxylate;6-(1-piperazinyl)-3-pyridinecarboxylic acid ethyl ester;6-piperazin-1-yl-nicotinic acid ethyl ester;SCHEMBL386639;DTXSID90566600;AMCQVTYZNLAJHD-UHFFFAOYSA-N;MFCD00894968;AKOS000151141;1-(5-ethoxycarbonyl-2-pyridyl)piperazine;CS-0298970;EN300-31151;ethyl 6-piperazin-1-ylnicotinate, AldrichCPR;G22769;Z239096308;3-Pyridinecarboxylic acid, 6-(1-piperazinyl)-, ethyl ester

Suppliers and Price of Ethyl 6-(piperazin-1-yl)nicotinate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
ethyl6-(piperazin-1-yl)pyridine-3-carboxylate
250mg
$ 265.00

Crysdot
Ethyl6-(piperazin-1-yl)nicotinate 95+%
1g
$ 299.00

Chemenu
ethyl6-(piperazin-1-yl)nicotinate 95%
1g
$ 282.00

American Custom Chemicals Corporation
ETHYL 6-PIPERAZIN-1-YLNICOTINATE 95.00%
5G
$ 1421.65

American Custom Chemicals Corporation
ETHYL 6-PIPERAZIN-1-YLNICOTINATE 95.00%
2.5G
$ 1147.43

American Custom Chemicals Corporation
ETHYL 6-PIPERAZIN-1-YLNICOTINATE 95.00%
1G
$ 808.89

Alichem
Ethyl6-(piperazin-1-yl)nicotinate
1g
$ 400.00

AK Scientific
Ethyl6-(piperazin-1-yl)nicotinate
5g
$ 1505.00

AK Scientific
Ethyl6-(piperazin-1-yl)nicotinate
2.5g
$ 1059.00

Total 10 raw suppliers

Chemical Property of Ethyl 6-(piperazin-1-yl)nicotinate

Chemical Property:

Vapor Pressure:0mmHg at 25°C
Refractive Index:1.538
Boiling Point:405.3°Cat760mmHg
Flash Point:198.9°C
PSA：54.46000
Density:1.145g/cm³
LogP:1.06170
Storage Temp.:2-8°C
XLogP3:0.9
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:4
Exact Mass:235.132076794
Heavy Atom Count:17
Complexity:254

Purity/Quality:

97% ^*data from raw suppliers

ethyl6-(piperazin-1-yl)pyridine-3-carboxylate ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCOC(=O)C1=CN=C(C=C1)N2CCNCC2

Technology Process of Ethyl 6-(piperazin-1-yl)nicotinate

There total 2 articles about Ethyl 6-(piperazin-1-yl)nicotinate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.6%

: 110-85-0
piperazine

: 49608-01-7
6-chloro-3-pyridinecarboxylic acid ethyl ester

: 132521-78-9
1-(5-ethoxycarbonyl-pyridin-2-yl)piperazine

Guidance literature:: With potassium carbonate; In acetonitrile; at 100 ℃; for 12h; Inert atmosphere;

Reference yield:

: 49608-01-7
6-chloro-3-pyridinecarboxylic acid ethyl ester

: 57260-71-6
1-t-Butoxycarbonylpiperazine

: 132521-78-9
1-(5-ethoxycarbonyl-pyridin-2-yl)piperazine

Guidance literature:: With potassium carbonate; trifluoroacetic acid; In dichloromethane; water; N,N-dimethyl-formamide;

Reference yield: 79.0%

: 23147-58-2,110822-84-9,110822-85-0,77431-49-3
glycolaldehyde dimer

: 132521-78-9
1-(5-ethoxycarbonyl-pyridin-2-yl)piperazine

: 214907-24-1
[2-(4-fluorophenyl)vinyl]boronic acid

: 944541-40-6
C₂₂H₂₆FN₃O₃

Guidance literature:: glycolaldehyde dimer; 1-(5-ethoxycarbonyl-pyridin-2-yl)piperazine; [2-(4-fluorophenyl)vinyl]boronic acid; In ethanol; at 20 ℃; for 15h;

With hydrogenchloride; In diethyl ether; water; at 5 ℃;

With potassium carbonate; In water;