Methyl-1-phenethyl-5-phenylimidazole-4-carboxylate

Base Information

Chemical Name:Methyl-1-phenethyl-5-phenylimidazole-4-carboxylate
CAS No.:130740-21-5
Molecular Formula:C19H18 N2 O2
Molecular Weight:306.35842
Hs Code.:2933290090
DSSTox Substance ID:DTXSID70562544
Nikkaji Number:J341.376D
Wikidata:Q82446757
Mol file:130740-21-5.mol

Synonyms:130740-21-5;METHYL-1-PHENETHYL-5-PHENYLIMIDAZOLE-4-CARBOXYLATE;Methyl 1-phenethyl-5-phenyl-1H-imidazole-4-carboxylate;methyl 5-phenyl-1-(2-phenylethyl)imidazole-4-carboxylate;Methyl 5-phenyl-1-(2-phenylethyl)-1H-imidazole-4-carboxylate;SCHEMBL5795140;DTXSID70562544

Suppliers and Price of Methyl-1-phenethyl-5-phenylimidazole-4-carboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
METHYL-1-PHENETHYL-5-PHENYLIMIDAZOLE-4-CARBOXYLATE 95.00%
5MG
$ 496.99

Total 4 raw suppliers

Chemical Property of Methyl-1-phenethyl-5-phenylimidazole-4-carboxylate

Chemical Property:

PSA：44.12000
LogP:3.57940
XLogP3:3.8
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:6
Exact Mass:306.136827821
Heavy Atom Count:23
Complexity:376

Purity/Quality:

98% ^*data from raw suppliers

METHYL-1-PHENETHYL-5-PHENYLIMIDAZOLE-4-CARBOXYLATE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC(=O)C1=C(N(C=N1)CCC2=CC=CC=C2)C3=CC=CC=C3

Technology Process of Methyl-1-phenethyl-5-phenylimidazole-4-carboxylate

There total 3 articles about Methyl-1-phenethyl-5-phenylimidazole-4-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 78.0%

: 533886-71-4
Methyl (E)/(Z)-3-Bromo-2-isocyanocinnamate

: 64-04-0
phenethylamine

: 130740-21-5
Methyl 1-Phenethyl-5-phenylimidazole-4-carboxylate

Guidance literature:: With triethylamine; In N,N,N,N,N,N-hexamethylphosphoric triamide; for 6h; Ambient temperature;
DOI:10.1055/s-1990-27013

Reference yield:

: 1265278-17-8
(Z)-methyl β-bromo-α-formylaminocinnamate

: 130740-21-5
Methyl 1-Phenethyl-5-phenylimidazole-4-carboxylate

Guidance literature:: Multi-step reaction with 2 steps

1: 90 percent / POCl₃, NEt₃ / CH₂Cl₂ / 2 h / Ambient temperature

2: 78 percent / NEt₃ / hexamethylphosphoric acid triamide / 6 h / Ambient temperature

With triethylamine; trichlorophosphate; In N,N,N,N,N,N-hexamethylphosphoric triamide; dichloromethane;
DOI:10.1055/s-1990-27013