2-(4-Hydroxy-phenyl)-N-phenyl-acetamide

Base Information

Chemical Name:2-(4-Hydroxy-phenyl)-N-phenyl-acetamide
CAS No.:131179-71-0
Molecular Formula:C14H13 N O2
Molecular Weight:227.263
Hs Code.:2924299090
European Community (EC) Number:676-037-7
DSSTox Substance ID:DTXSID20460526
Nikkaji Number:J1.364.286I
Wikidata:Q82284591
Mol file:131179-71-0.mol

Synonyms:131179-71-0;2-(4-Hydroxy-phenyl)-N-phenyl-acetamide;2-(4-hydroxyphenyl)-N-phenylacetamide;SCHEMBL4420808;DTXSID20460526;MFCD06796563;AKOS017179106;Benzeneacetamide, 4-hydroxy-N-phenyl-;2-(4-hydroxyphenyl)-N-phenyl acetamide;AS-36971;CS-0172743

Suppliers and Price of 2-(4-Hydroxy-phenyl)-N-phenyl-acetamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
2-(4-Hydroxyphenyl)-N-phenylacetamide
100mg
$ 75.00

Crysdot
2-(4-Hydroxyphenyl)-N-phenylacetamide 97%
10g
$ 305.00

Crysdot
2-(4-Hydroxyphenyl)-N-phenylacetamide 97%
25g
$ 561.00

American Custom Chemicals Corporation
2-(4-HYDROXY-PHENYL)-N-PHENYL-ACETAMIDE 95.00%
5G
$ 1079.35

Alichem
2-(4-Hydroxyphenyl)-N-phenylacetamide
25g
$ 555.66

AK Scientific
2-(4-Hydroxy-phenyl)-N-phenyl-acetamide
25g
$ 840.00

AK Scientific
2-(4-Hydroxy-phenyl)-N-phenyl-acetamide
1g
$ 147.00

Total 10 raw suppliers

Chemical Property of 2-(4-Hydroxy-phenyl)-N-phenyl-acetamide

Chemical Property:

Vapor Pressure:2.51E-10mmHg at 25°C
Melting Point:138 °C
Refractive Index:1.657
Boiling Point:492.6°Cat760mmHg
PKA:9.87±0.15(Predicted)
Flash Point:251.7°C
PSA：49.33000
Density:1.251g/cm³
LogP:2.64640
Storage Temp.:2-8°C
XLogP3:2.7
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:3
Exact Mass:227.094628657
Heavy Atom Count:17
Complexity:241

Purity/Quality:

97% ^*data from raw suppliers

2-(4-Hydroxyphenyl)-N-phenylacetamide ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C(C=C1)NC(=O)CC2=CC=C(C=C2)O

Technology Process of 2-(4-Hydroxy-phenyl)-N-phenyl-acetamide

There total 4 articles about 2-(4-Hydroxy-phenyl)-N-phenyl-acetamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

: 156-38-7
4-hydroxyphenylacetate

: 62-53-3
aniline

: 131179-71-0
4-<(anilinocarbonyl)methyl>phenol

Guidance literature:: With Fe⁽³⁺⁾-K-10 montmorillonite clay; In chloroform; for 8h; Heating;
DOI:10.1021/jo0204202

Reference yield:

: 18982-18-8
allyl 4-hydroxybenzoate

: 62-53-3
aniline

: 18107-18-1
diazomethyl-trimethyl-silane

: 131179-71-0
4-<(anilinocarbonyl)methyl>phenol

Guidance literature:: allyl 4-hydroxybenzoate; aniline; diazomethyl-trimethyl-silane;

With trifluoroacetic acid; In dichloromethane; at 20 ℃; for 0.5h;
DOI:10.1016/S0040-4020(00)00440-3

Reference yield:

: 99-96-7
4-hydroxy-benzoic acid

: 131179-71-0
4-<(anilinocarbonyl)methyl>phenol

Guidance literature:: Multi-step reaction with 3 steps

1.1: thionyl chloride / dimethylformamide; CH₂Cl₂ / 0.5 h / 20 °C

2.1: dimethylformamide; CH₂Cl₂ / 2 h / 20 °C

3.2: TFA / CH₂Cl₂ / 0.5 h / 20 °C

With thionyl chloride; In dichloromethane; N,N-dimethyl-formamide; 1.1: Substitution / 2.1: Esterification / 3.1: Solid phase reaction / 3.2: cleavage;
DOI:10.1016/S0040-4020(00)00440-3