2-Acetoxymethyl-4-benzyloxybut-1-yl acetate

Base Information

Chemical Name:2-Acetoxymethyl-4-benzyloxybut-1-yl acetate
CAS No.:131266-10-9
Molecular Formula:C16H22 O5
Molecular Weight:294.348
Hs Code.:
European Community (EC) Number:407-140-5
DSSTox Substance ID:DTXSID70430855
Wikidata:Q82244591
Mol file:131266-10-9.mol

Synonyms:131266-10-9;2-(ACETOXYMETHYL)-4-(BENZYLOXY)BUTYL ACETATE;2-Acetoxymethyl-4-benzyloxybut-1-yl acetate;EC 407-140-5;[2-(acetyloxymethyl)-4-phenylmethoxybutyl] acetate;1,3-Propanediol, 2-[2-(phenylmethoxy)ethyl]-, 1,3-diacetate;SCHEMBL5930158;DTXSID70430855;BLAYUKYLAGRIMQ-UHFFFAOYSA-N;2-acetoxymethyl-4-benzyloxy-but-1-yl acetate;2-[(Acetyloxy)methyl]-4-(benzyloxy)butyl acetate (non-preferred name)

Suppliers and Price of 2-Acetoxymethyl-4-benzyloxybut-1-yl acetate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 6 raw suppliers

Chemical Property of 2-Acetoxymethyl-4-benzyloxybut-1-yl acetate

Chemical Property:

Vapor Pressure:0mmHg at 25°C
Refractive Index:1.495
Boiling Point:389.674ºC at 760 mmHg
Flash Point:169.179ºC
PSA：61.83000
Density:1.098g/cm3
LogP:2.33570
XLogP3:2
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:11
Exact Mass:294.14672380
Heavy Atom Count:21
Complexity:292

Purity/Quality:: 99.9% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:
Statements: 52/53
Safety Statements: 61

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(=O)OCC(CCOCC1=CC=CC=C1)COC(=O)C

Technology Process of 2-Acetoxymethyl-4-benzyloxybut-1-yl acetate

There total 2 articles about 2-Acetoxymethyl-4-benzyloxybut-1-yl acetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

: 77661-80-4
2-(2-(benzyloxy)ethyl)propane-1,3-diol

: 131266-10-9
2-acetoxymethyl-4-benzyloxybutyl acetate

Guidance literature:: With pyridine; dmap; acetic anhydride; In dichloromethane;

Reference yield: 94.0%

: 108-24-7
acetic anhydride

: 77661-80-4
2-(2-(benzyloxy)ethyl)propane-1,3-diol

: 131266-10-9
2-acetoxymethyl-4-benzyloxybutyl acetate

Guidance literature:: With pyridine; dmap; In dichloromethane; at 0 ℃; for 1h;
DOI:10.1016/S0040-4020(01)87878-9

Reference yield:

: 131266-10-9
2-acetoxymethyl-4-benzyloxybutyl acetate

: 104227-87-4
9-(4-acetoxy-3-acetoxymethylbutyl)-2-aminopurine

Guidance literature:: Multi-step reaction with 4 steps

1: H₂ / 10percent Pd/C / ethanol / 18 h / Ambient temperature

2: Et₃N / CH₂Cl₂ / 1 h / -5 °C

3: NaI / acetone / 2 h / Heating

4: 59 percent / K₂CO₃ / dimethylformamide / 18 h / Ambient temperature

With hydrogen; potassium carbonate; triethylamine; sodium iodide; palladium on activated charcoal; In ethanol; dichloromethane; N,N-dimethyl-formamide; acetone;
DOI:10.1016/S0040-4020(01)87878-9