77661-80-4Relevant articles and documents
NOVEL HETEROAROMATIC AMIDE DERIVATIVE AND MEDICINE CONTAINING SAME
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, (2021/07/24)
A compound selectively inhibiting Nav1.7 over Nav1.5 is provided. A heteroaromatic amide derivative or salt thereof showing high efficacy for various diseases associated with Nav1.7 such as pain, represented by the general formula (I) [wherein, X1-X2 is N-C or C-N, Y1 , Y2, Y3 and Y4 are -CH2-, -CR4aH- or -O- and so on, Z1 is-O- and so on, ring A is a 3- to 7-membered monocyclic aromatic ring and so on, R1a and R1b are a hydrogen atom or a halogen atom and so on, R2 is a hydrogen atom and so on, R3a, R3b and R3c are a hydrogen atom or an optionally substituted C1-C6 haloalkyl group and so on, R4a, R4b and R4c are, an optionally substituted C1-C6 haloalkyl group or C1-C6 haloalkoxy group and so on, R5a is a hydrogen atom and so on, R5a and R5b together form -CH2O- and so on, R6a and R6b are a hydrogen atom and so on, n is 1 or 2.].
Compound, liquid crystal composition, liquid crystal display element and liquid crystal display
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Paragraph 0176; 0184-0186, (2020/02/27)
The present invention relates to a compound, a liquid crystal composition, a liquid crystal display element, and a liquid crystal display. The compound is a compound represented by a formula I shown in the description. The liquid crystal composition of the present invention contains the compound represented by the formula I. The compound represented by the formula I has the advantages of good mutual solubility with other compounds and good UV resistance. As a reactive mesogen (RM), the compound has the advantages of good mutual solubility, high polymerization activity (less monomer residue), and strong binding ability. The compound can not only be used as a self-aligning agent for the liquid crystal compositions alone, but also can be used as a vertical alignment material for copolymerization with other RMs so as to be used as a self-aligning agent for the liquid crystal compositions in a PSA (polymer-supported alignment) and PS (polymer-stabilized) mode, the PI preparation process canbe avoided, the preparation process of the liquid crystal display element or liquid crystal display can be simplified, and the production efficiency can be improved.
LIQUID CRYSTAL MIXTURE AND LIQUID CRYSTAL DISPLAY
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Page/Page column 183, (2020/12/29)
The invention relates to a compound of formula (I), wherein R11, R21, A11, A, Z, X11, X21, Y11, Y12, Sp11, Sp21, o and p have one of the meanings as given in claim 1. The invention further relates to method of production of a compound of formula (I), to the use of said compounds in LC media and to LC media comprising one or more compounds of formula (I). Further, the invention relates to a method of production of such LC media, to the use of such media in LC devices, and to LC device comprising a LC medium according to the present invention.The present invention further relates to a process for the fabrication such liquid crystal display and to the use of the liquid crystal mixtures according to the invention for the fabrication of such liquid crystal display.