2H-Pyrrol-2-one,1,5-dihydro-4-methoxy-5-(1-methylethyl)-,(S)-(9CI)

Base Information

Chemical Name:2H-Pyrrol-2-one,1,5-dihydro-4-methoxy-5-(1-methylethyl)-,(S)-(9CI)
CAS No.:133908-08-4
Molecular Formula:C8H13NO2
Molecular Weight:155.19
Hs Code.:
Mol file:133908-08-4.mol

Synonyms:2H-Pyrrol-2-one,1,5-dihydro-4-methoxy-5-(1-methylethyl)-,(S)-(9CI)

Suppliers and Price of 2H-Pyrrol-2-one,1,5-dihydro-4-methoxy-5-(1-methylethyl)-,(S)-(9CI)

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 2H-Pyrrol-2-one,1,5-dihydro-4-methoxy-5-(1-methylethyl)-,(S)-(9CI)

Chemical Property:

Melting Point:148 - 150 °C
PSA：38.33000
LogP:0.99990

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

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Technology Process of 2H-Pyrrol-2-one,1,5-dihydro-4-methoxy-5-(1-methylethyl)-,(S)-(9CI)

There total 8 articles about 2H-Pyrrol-2-one,1,5-dihydro-4-methoxy-5-(1-methylethyl)-,(S)-(9CI) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

: C₂₃H₂₃NO₄

: 133908-08-4
iheyanone

Guidance literature:: With piperidine; In acetonitrile; at 20 ℃; for 0.25h;
DOI:10.1021/jm501439w

Reference yield:

: 934197-81-6
2-isopropyl-3-methoxy-5-oxo-2,5-dihydro-pyrrole-1-carboxylic acid tert-butyl ester

: 133908-08-4
iheyanone

Guidance literature:: With trifluoroacetic acid; In dichloromethane; at 0 ℃; for 0.5h;
DOI:10.1016/j.tet.2007.01.035

Reference yield:

: 112700-40-0
tert-butyl (S)-3-hydroxy-2-isopropyl-5-oxo-2,5-dihydro-1H-pyrrole-1-carboxylate

: 133908-08-4
iheyanone

Guidance literature:: Multi-step reaction with 2 steps

1: Ph₃P; diethyl azodicarboxylate / tetrahydrofuran; toluene / 2 h / 20 °C

2: TFA / CH₂Cl₂ / 0.5 h / 0 °C

With triphenylphosphine; trifluoroacetic acid; diethylazodicarboxylate; In tetrahydrofuran; dichloromethane; toluene; 1: Mitsunobu reaction;
DOI:10.1016/j.tet.2007.01.035