1-Hydrazino-4-(3,5-dimethyl)-1-pyrazolyl-5H-pyridazino(4,5-b)indole

Base Information

• Chemical Name: 1-Hydrazino-4-(3,5-dimethyl)-1-pyrazolyl-5H-pyridazino(4,5-b)indole
• CAS No.: 135561-92-1
• Molecular Formula: C15H15N7
• Molecular Weight: 0
• DSSTox Substance ID: DTXSID60159467
• Nikkaji Number: J457.213K
• Wikidata: Q83027803
• ChEMBL ID: CHEMBL320615
• Mol file: 135561-92-1.mol

Synonyms:1-hydrazino-4-(3,5-dimethyl)-1-pyrazolyl-5H-pyridazino(4,5-b)indole;1-hydrazino-4-(3,5-dimethyl)-1-pyrazolyl-5H-pyridazino(4,5-b)indole hydrochloride;HDPPI

Chemical Property of 1-Hydrazino-4-(3,5-dimethyl)-1-pyrazolyl-5H-pyridazino(4,5-b)indole

Chemical Property:

• Vapor Pressure: 1.25E-18mmHg at 25°C
• Refractive Index: 1.817
• Boiling Point: 685.3°Cat760mmHg
• Flash Point: 368.2°C
• PSA: 100.67000
• Density: 1.54g/cm³
• LogP: 2.32140
• XLogP3: 2
• Hydrogen Bond Donor Count: 3
• Hydrogen Bond Acceptor Count: 5
• Rotatable Bond Count: 2
• Exact Mass: 293.13889351
• Heavy Atom Count: 22
• Complexity: 405

Purity/Quality:

98%min ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: CC1=CC(=NN1C2=NN=C(C3=C2NC4=CC=CC=C43)NN)C

Technology Process of 1-Hydrazino-4-(3,5-dimethyl)-1-pyrazolyl-5H-pyridazino(4,5-b)indole

There total 3 articles about 1-Hydrazino-4-(3,5-dimethyl)-1-pyrazolyl-5H-pyridazino(4,5-b)indole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 70.0%

1-chloro-4-(3,5-dimethylpyrazolyl)-5H-pyridazino<4,5-b>indole (135561-91-0) → 1-hydrazino-4-(3,5-dimethyl-1-pyrazolyl)pyridazino<4,5-b>indole (135561-92-1)

Guidance literature:

With hydrazine hydrate; for 6h; Heating;

DOI:10.1021/jm00114a010

Reference yield:

1-chloro-4-hydrazino-5H-pyridazino<4,5-b>indole (80985-58-6) → 1-hydrazino-4-(3,5-dimethyl-1-pyrazolyl)pyridazino<4,5-b>indole (135561-92-1)

Guidance literature:

Multi-step reaction with 2 steps

1: 84 percent / 8 h / Heating

2: 70 percent / 100percent hydrazine hydrate / 6 h / Heating

With hydrazine hydrate;

DOI:10.1021/jm00114a010

Reference yield:

acetylacetone (123-54-6,81235-32-7) → 1-hydrazino-4-(3,5-dimethyl-1-pyrazolyl)pyridazino<4,5-b>indole (135561-92-1)

Guidance literature:

Multi-step reaction with 2 steps

1: 84 percent / 8 h / Heating

2: 70 percent / 100percent hydrazine hydrate / 6 h / Heating

With hydrazine hydrate;

DOI:10.1021/jm00114a010

upstream raw materials:

1-chloro-4-(3,5-dimethylpyrazolyl)-5H-pyridazino<4,5-b>indole

1-chloro-4-hydrazino-5H-pyridazino<4,5-b>indole

acetylacetone