1-(9H-fluoren-9-ylmethoxycarbonyl)azetidine-2-carboxylic Acid

Base Information

Chemical Name:1-(9H-fluoren-9-ylmethoxycarbonyl)azetidine-2-carboxylic Acid
CAS No.:136552-16-4
Molecular Formula:C₉H₁₁NO₄
Molecular Weight:197.191
Hs Code.:
European Community (EC) Number:841-001-3
DSSTox Substance ID:DTXSID50403224
Mol file:136552-16-4.mol

Synonyms:1-Fmoc-2-azetidinecarboxylic acid;184763-07-3;136552-16-4;Fmoc-L-Azetidine-2-carboxylicacid;1-(9H-fluoren-9-ylmethoxycarbonyl)azetidine-2-carboxylic Acid;1-(((9H-Fluoren-9-yl)methoxy)carbonyl)azetidine-2-carboxylic acid;Fmoc-L-azetidine-2-carboxylic acid;1-{[(9H-fluoren-9-yl)methoxy]carbonyl}azetidine-2-carboxylic acid;SCHEMBL1847817;DTXSID50403224;BCP14279;AKOS015912097;AB93479;MB01828;SB48481;SY059478;FT-0643256;FT-0656336;A50765;EN300-657416;A807090;Z2050424817;1-[9H-fluoren-9-ylmethoxy(oxo)methyl]-2-azetidinecarboxylic acid

Suppliers and Price of 1-(9H-fluoren-9-ylmethoxycarbonyl)azetidine-2-carboxylic Acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
2-(2-METHOXY-6-NITRO-PHENYL)ETHANOL 95.00%
5G
$ 1608.11

American Custom Chemicals Corporation
2-(2-METHOXY-6-NITRO-PHENYL)ETHANOL 95.00%
1G
$ 812.54

Total 11 raw suppliers

Chemical Property of 1-(9H-fluoren-9-ylmethoxycarbonyl)azetidine-2-carboxylic Acid

Chemical Property:

PSA：66.84000
LogP:3.03230
XLogP3:3
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:4
Exact Mass:323.11575802
Heavy Atom Count:24
Complexity:486

Purity/Quality:

97% ^*data from raw suppliers

2-(2-METHOXY-6-NITRO-PHENYL)ETHANOL 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CN(C1C(=O)O)C(=O)OCC2C3=CC=CC=C3C4=CC=CC=C24

Technology Process of 1-(9H-fluoren-9-ylmethoxycarbonyl)azetidine-2-carboxylic Acid

There total 5 articles about 1-(9H-fluoren-9-ylmethoxycarbonyl)azetidine-2-carboxylic Acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

: 1090514-05-8
(2-methoxy-6-nitro-phenyl)-acetic acid ethyl ester

: 136552-16-4
2-(2-methoxy-6-nitrophenyl)-1-ethanol

Guidance literature:: (2-methoxy-6-nitro-phenyl)-acetic acid ethyl ester; With diisobutylaluminium hydride; In tetrahydrofuran; toluene; at -5 - 0 ℃;

With hydrogenchloride; water; In tetrahydrofuran; toluene;

Reference yield:

: 4837-88-1
6-methoxy-2-nitrotoluene

: 136552-16-4
2-(2-methoxy-6-nitrophenyl)-1-ethanol

Guidance literature:: Multi-step reaction with 4 steps

1: N-Bromosuccinimide / dibenzoyl peroxide / tetrachloromethane / 3 h / Reflux

2: ethanol / 16 h / Reflux

3: sulfuric acid / 16 h / Reflux

4: diisobutylaluminium hydride / tetrahydrofuran; toluene / -5 - 0 °C

With N-Bromosuccinimide; sulfuric acid; diisobutylaluminium hydride; dibenzoyl peroxide; In tetrahydrofuran; tetrachloromethane; ethanol; toluene;

Reference yield:

: 19689-86-2
2-nitro-6-methoxybenzyl bromide

: 136552-16-4
2-(2-methoxy-6-nitrophenyl)-1-ethanol

Guidance literature:: Multi-step reaction with 3 steps

1: ethanol / 16 h / Reflux

2: sulfuric acid / 16 h / Reflux

3: diisobutylaluminium hydride / tetrahydrofuran; toluene / -5 - 0 °C

With sulfuric acid; diisobutylaluminium hydride; In tetrahydrofuran; ethanol; toluene;