PARA-NITROBENZYLBROMIDE

Base Information

• Chemical Name: PARA-NITROBENZYLBROMIDE
• CAS No.: 19689-86-2
• Molecular Formula: C8H8 Br N O3
• Molecular Weight: 246.06
• Hs Code.: 2909309090
• Mol file: 19689-86-2.mol

Synonyms:Anisole,2-(bromomethyl)-3-nitro- (8CI); 2-(Bromomethyl)-1-methoxy-3-nitrobenzene;2-Bromomethyl-3-methoxynitrobenzene; 2-Methoxy-6-nitrobenzyl bromide; a-Bromo-2-methoxy-6-nitrotoluene

Chemical Property of PARA-NITROBENZYLBROMIDE

Chemical Property:

• Vapor Pressure: 0.000755mmHg at 25°C
• Boiling Point: 316.6°Cat760mmHg
• Flash Point: 145.3°C
• PSA: 55.05000
• Density: 1.589g/cm³
• LogP: 3.02150

Purity/Quality:

97% ^*data from raw suppliers

2-(Bromomethyl)-1-methoxy-3-nitrobenzene ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of PARA-NITROBENZYLBROMIDE

There total 5 articles about PARA-NITROBENZYLBROMIDE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

6-methoxy-2-nitrotoluene (4837-88-1) → 2-nitro-6-methoxybenzyl bromide (19689-86-2)

Guidance literature:

With N-Bromosuccinimide; 2,2'-azobis(isobutyronitrile); In tetrachloromethane; Heating;

DOI:10.1016/j.bmc.2007.07.005

Reference yield: 44.0%

→ 2-nitro-6-methoxybenzyl bromide (19689-86-2)

Guidance literature:

Reference yield:

3-nitro-o-cresol (5460-31-1) → 2-nitro-6-methoxybenzyl bromide (19689-86-2)

Guidance literature:

Multi-step reaction with 2 steps

1: NaOMe / methanol

2: NBS, (PhCO)2O₂ / CCl₄ / Irradiation

With N-Bromosuccinimide; sodium methylate; dibenzoyl peroxide; In methanol; tetrachloromethane;

DOI:10.1016/S0040-4020(01)96342-2

upstream raw materials:

6-methoxy-2-nitrotoluene

(2-methoxy-6-nitrophenyl)methanol

3-nitro-o-cresol

3-nitro-o-tolylamine

Downstream raw materials:

2-methoxy-6-nitrobenzaldehyde

4-nitro-2,3-dihydro-benzofuran

(2-methoxy-6-nitro-phenyl)-acetic acid ethyl ester

2-(2-methoxy-6-nitrophenyl)-1-ethanol