1-Oxaspiro[4.5]decan-2-one, 4-(chloroacetyl)-(9CI)

Base Information

Chemical Name:1-Oxaspiro[4.5]decan-2-one, 4-(chloroacetyl)-(9CI)
CAS No.:137180-64-4
Molecular Formula:C11H15ClO3
Molecular Weight:230.688
Hs Code.:
DSSTox Substance ID:DTXSID10394760
Mol file:137180-64-4.mol

Synonyms:137180-64-4;4-(2-chloroacetyl)-1-oxaspiro[4.5]decan-2-one;1-Oxaspiro[4.5]decan-2-one, 4-(chloroacetyl)- (9CI);DTXSID10394760;STK698946;AKOS005521453;4-(chloroacetyl)-1-oxaspiro[4.5]decan-2-one

Suppliers and Price of 1-Oxaspiro[4.5]decan-2-one, 4-(chloroacetyl)-(9CI)

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
1-OXASPIRO[4.5]DECAN-2-ONE, 4-(CHLOROACETYL)- 95.00%
5MG
$ 505.27

Total 2 raw suppliers

Chemical Property of 1-Oxaspiro[4.5]decan-2-one, 4-(chloroacetyl)-(9CI)

Chemical Property:

PSA：43.37000
LogP:2.06030
XLogP3:1.8
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:230.0709720
Heavy Atom Count:15
Complexity:282

Purity/Quality:

99% ^*data from raw suppliers

1-OXASPIRO[4.5]DECAN-2-ONE, 4-(CHLOROACETYL)- 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1CCC2(CC1)C(CC(=O)O2)C(=O)CCl

Technology Process of 1-Oxaspiro[4.5]decan-2-one, 4-(chloroacetyl)-(9CI)

There total 3 articles about 1-Oxaspiro[4.5]decan-2-one, 4-(chloroacetyl)-(9CI) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

: 186581-53-3,908094-01-9,334-88-3
diazomethane

: 30990-88-6
2-oxo-1-oxospiro<4,5>decane-4-carboxyl chloride

: 137180-64-4
2-oxo-4-chloroacetyl-1-oxaspiro<4,5>decane

Guidance literature:: With hydrogenchloride; In diethyl ether; for 1h;
DOI:10.1007/BF01171302

Reference yield:

: 2819-56-9
2-oxo-1-oxospiro<4,5>decane-4-carboxylic acid

: 137180-64-4
2-oxo-4-chloroacetyl-1-oxaspiro<4,5>decane

Guidance literature:: Multi-step reaction with 2 steps

1: 94 percent / SOCl₂ / benzene / 6 h

2: 87 percent / conc. HCl / diethyl ether / 1 h

With hydrogenchloride; thionyl chloride; In diethyl ether; benzene;
DOI:10.1007/BF01171302

Reference yield:

: 134515-27-8
2-oxo-1-oxaspiro<4,5>decan-3,4-dicarboxylic acid diethyl ester

: 137180-64-4
2-oxo-4-chloroacetyl-1-oxaspiro<4,5>decane

Guidance literature:: Multi-step reaction with 3 steps

1: 70 percent / conc. HCl / 5 h / Heating

2: 94 percent / SOCl₂ / benzene / 6 h

3: 87 percent / conc. HCl / diethyl ether / 1 h

With hydrogenchloride; thionyl chloride; In diethyl ether; benzene;
DOI:10.1007/BF01171302