Ethanone, 1-bicyclo[1.1.1]pent-1-yl- (9CI)

Base Information

• Chemical Name: Ethanone, 1-bicyclo[1.1.1]pent-1-yl- (9CI)
• CAS No.: 137335-61-6
• Molecular Formula: C7H10O
• Molecular Weight: 110.1537
• Hs Code.: 2914290090
• Mol file: 137335-61-6.mol

Synonyms:Ethanone, 1-bicyclo[1.1.1]pent-1-yl- (9CI)

Chemical Property of Ethanone, 1-bicyclo[1.1.1]pent-1-yl- (9CI)

Chemical Property:

• PSA: 17.07000
• LogP: 1.37550

Purity/Quality:

99% ^*data from raw suppliers

1-(bicyclo[1.1.1]pentan-1-yl)ethan-1-one 97% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Ethanone, 1-bicyclo[1.1.1]pent-1-yl- (9CI)

There total 2 articles about Ethanone, 1-bicyclo[1.1.1]pent-1-yl- (9CI) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

diethyl ether (60-29-7,927820-24-4) + [1.1.1]propellane (35634-10-7) → bicyclo[1.1.1]pentane-1-carboxylic acid (22287-28-1) + 1-acetylbicyclo<1.1.1>pentane (137335-61-6) + 1-(1-acetoxyethyl)bicyclo<1.1.1>pentane (137335-60-5) + <2>staffane-3-carboxylic acid (137335-08-1)

Guidance literature:

With ruthenium(IV) oxide; Perbenzoic acid; Multistep reaction. Further byproducts given. Yields of byproduct given; 1.) irrad., 8 h, 2.) CCl₄, Chlorox;

DOI:10.1021/ja00028a029

Reference yield:

bicyclo[1.1.1]pentane-1-carboxylic acid (22287-28-1) + methyllithium (917-54-4) → 1-acetylbicyclo<1.1.1>pentane (137335-61-6)

Guidance literature:

With chloro-trimethyl-silane; In tetrahydrofuran; for 18h; Ambient temperature;

DOI:10.1002/(SICI)1099-1395(199603)9:3<168::AID-POC766>3.0.CO;2-V

upstream raw materials:

diethyl ether

[1.1.1]propellane

bicyclo[1.1.1]pentane-1-carboxylic acid

methyllithium

Refernces

• 1、 Kaszynski, Piotr,Friedli, Andrienne C.,Michl, Josef. "Toward a molecular-size "Tinkertoy" construction set. Preparation of terminally functionalized [n]staffanes from [1.1.1]propellane". . p. 601 - 620. Retrieved 2007/10/02.