2-(2,4-Dichlorophenoxy)benzaldehyde

Base Information

• Chemical Name: 2-(2,4-Dichlorophenoxy)benzaldehyde
• CAS No.: 86309-06-0
• Molecular Formula: C13H8 Cl2 O2
• Molecular Weight: 267.111
• Hs Code.: 2913000090
• DSSTox Substance ID: DTXSID20376951
• Wikidata: Q82165911
• Mol file: 86309-06-0.mol

Synonyms:2-(2,4-dichlorophenoxy)benzaldehyde;86309-06-0;2-(2,4-Dichlorophenoxy)Benzenecarbaldehyde;SCHEMBL6957428;DTXSID20376951;AEAYPCKDEZKJMI-UHFFFAOYSA-N;MFCD01568767;AKOS005069724;CS-0330830;FT-0680074;12N-058;A863246;J-505472

Chemical Property of 2-(2,4-Dichlorophenoxy)benzaldehyde

Chemical Property:

• Vapor Pressure: 7.18E-05mmHg at 25°C
• Melting Point: 58-60°C
• Boiling Point: 147°C 0,1mm
• Flash Point: 138.1°C
• PSA: 26.30000
• Density: 1.365g/cm³
• LogP: 4.59820
• XLogP3: 4.2
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 3
• Exact Mass: 265.9901349
• Heavy Atom Count: 17
• Complexity: 260

Purity/Quality:

97% ^*data from raw suppliers

2-(2,4-Dichlorophenoxy)benzenecarbaldehyde >95% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=C(C(=C1)C=O)OC2=C(C=C(C=C2)Cl)Cl

Technology Process of 2-(2,4-Dichlorophenoxy)benzaldehyde

There total 4 articles about 2-(2,4-Dichlorophenoxy)benzaldehyde which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 84.0%

2-Fluorobenzaldehyde (446-52-6) + 2,4-dichlorophenol (120-83-2,40477-79-0) → 2-(2,4-dichlorophenoxy)benzaldehyde (86309-06-0)

Guidance literature:

With potassium carbonate; In N,N-dimethyl acetamide; at 170 ℃; for 3h; Inert atmosphere;

DOI:10.1002/anie.201103599

Reference yield:

2-(2,4-dichlorophenoxy)benzonitrile (175136-80-8) → 2-(2,4-dichlorophenoxy)benzaldehyde (86309-06-0)

Guidance literature:

With diisobutylaluminium hydride; In tetrahydrofuran; n-heptane; water; ethyl acetate; toluene;

Reference yield:

sodium 2,4-dichlorophenolate (3757-76-4) + ortho-bromobenzaldehyde (6630-33-7) → 2-(2,4-dichlorophenoxy)benzaldehyde (86309-06-0)

Guidance literature:

With copper; 2,4-dichlorophenol; at 110 ℃; for 48h;

DOI:10.1021/jm00364a004

upstream raw materials:

sodium 2,4-dichlorophenolate

ortho-bromobenzaldehyde

potassium 2-formylphenolate

1,2,4-Trichlorobenzene

Downstream raw materials:

1-[2-(2,4-dichlorophenoxy)phenyl]methanol

C₁₅H₁₅Cl₂NO

(2-hydroxyphenyl)-(2,4-dichlorophenyl)methanone

2,4-dichloro-9H-xanthen-9-one