Cyclopropene, 3,3-difluoro-1-hexyl- (9CI)

Base Information

• Chemical Name: Cyclopropene, 3,3-difluoro-1-hexyl- (9CI)
• CAS No.: 138101-01-6
• Molecular Formula: C9H14F2
• Molecular Weight: 160.2042664
• Mol file: 138101-01-6.mol

Synonyms:Cyclopropene, 3,3-difluoro-1-hexyl- (9CI)

Chemical Property of Cyclopropene, 3,3-difluoro-1-hexyl- (9CI)

Chemical Property:

• PSA: 0.00000
• LogP: 3.53210

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Cyclopropene, 3,3-difluoro-1-hexyl- (9CI)

There total 2 articles about Cyclopropene, 3,3-difluoro-1-hexyl- (9CI) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 83.0%

n-octyne (629-05-0) + (trifluoromethyl)trimethylsilane (81290-20-2) → 3,3-Difluoro-1-hexylcyclopropene (138101-01-6)

Guidance literature:

With sodium iodide; In tetrahydrofuran; at 120 ℃; for 0.166667h; under 6000.6 Torr; Inert atmosphere; Flow reactor;

DOI:10.1021/acs.orglett.6b00573

Reference yield: 77.0%

dibromodifluoromethane (75-61-6) + n-octyne (629-05-0) → 3,3-Difluoro-1-hexylcyclopropene (138101-01-6)

Guidance literature:

With potassium fluoride; 18-crown-6 ether; triphenylphosphine; In 1,2-dimethoxyethane; at 25 ℃;

DOI:10.1016/S0040-4020(01)89734-9

upstream raw materials:

dibromodifluoromethane

n-octyne

(trifluoromethyl)trimethylsilane

Refernces

• 1、 Bessard, Yves,Schlosser, Manfred. "gem-Difluorocyclopropenes by [1+2] cycloaddition reactions between difluorocarbene and acetylenes having terminal or internal triple bonds". . p. 7323 - 7328. Retrieved 2007/10/02.