(2-TERT-BUTOXYCARBONYLAMINO-6-FLUORO-PHENYL)-ACETIC ACID

Base Information

Chemical Name:(2-TERT-BUTOXYCARBONYLAMINO-6-FLUORO-PHENYL)-ACETIC ACID
CAS No.:138343-92-7
Molecular Formula:C13H16FNO4
Molecular Weight:269.2688432
Hs Code.:2924299090
Mol file:138343-92-7.mol

Synonyms:(2-TERT-BUTOXYCARBONYLAMINO-6-FLUORO-PHENYL)-ACETIC ACID

Suppliers and Price of (2-TERT-BUTOXYCARBONYLAMINO-6-FLUORO-PHENYL)-ACETIC ACID

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
2-(2-((tert-Butoxycarbonyl)amino)-6-fluorophenyl)aceticacid 95+%
1g
$ 475.00

American Custom Chemicals Corporation
(2-TERT-BUTOXYCARBONYLAMINO-6-FLUORO-PHENYL)-ACETIC ACID 95.00%
5MG
$ 501.75

Alichem
(2-tert-Butoxycarbonylamino-6-fluoro-phenyl)-aceticacid
250mg
$ 201.60

Total 3 raw suppliers

Chemical Property of (2-TERT-BUTOXYCARBONYLAMINO-6-FLUORO-PHENYL)-ACETIC ACID

Chemical Property:

Vapor Pressure:1.98E-05mmHg at 25°C
Refractive Index:1.553
Boiling Point:347.8°C at 760 mmHg
Flash Point:164.1°C
PSA：75.63000
Density:1.281g/cm³
LogP:2.87280

Purity/Quality:

99.0%min ^*data from raw suppliers

2-(2-((tert-Butoxycarbonyl)amino)-6-fluorophenyl)aceticacid 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of (2-TERT-BUTOXYCARBONYLAMINO-6-FLUORO-PHENYL)-ACETIC ACID

There total 4 articles about (2-TERT-BUTOXYCARBONYLAMINO-6-FLUORO-PHENYL)-ACETIC ACID which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: C₁₂H₁₄FLiNO₂^(1-)*Li⁽¹⁺⁾

: 124-38-9,18923-20-1
carbon dioxide

: 138343-92-7
(2-tert-Butoxycarbonylamino-6-fluoro-phenyl)-acetic acid

Guidance literature:: C₁₂H₁₄FLiNO₂^(1-)*Li⁽¹⁺⁾; carbon dioxide; In tetrahydrofuran; cyclohexane; at -45 - 20 ℃;

With hydrogenchloride; In tetrahydrofuran; cyclohexane; water; for 0.0833333 - 0.166667h; pH=2 - 3;

Reference yield:

: 24424-99-5
di-tert-butyl dicarbonate

: 138343-92-7
(2-tert-Butoxycarbonylamino-6-fluoro-phenyl)-acetic acid

Guidance literature:: Multi-step reaction with 2 steps

1: tetrahydrofuran / Heating

2: 1) s-BuLi / 1) THF, cyclohexane, -40 to -20 deg C, 2) -40 deg C, 1 min

With sec.-butyllithium; In tetrahydrofuran;
DOI:10.1055/s-1991-26597

Reference yield:

: 443-86-7
3-fluoro-2-methylaniline

: 138343-92-7
(2-tert-Butoxycarbonylamino-6-fluoro-phenyl)-acetic acid

Guidance literature:: Multi-step reaction with 2 steps

1: tetrahydrofuran / Heating

2: 1) s-BuLi / 1) THF, cyclohexane, -40 to -20 deg C, 2) -40 deg C, 1 min

With sec.-butyllithium; In tetrahydrofuran;
DOI:10.1055/s-1991-26597