6-Methylpyrimidine-4-carboxylic acid

Base Information

Chemical Name:6-Methylpyrimidine-4-carboxylic acid
CAS No.:138538-42-8
Molecular Formula:C6H6N2O2
Molecular Weight:138.12404
Hs Code.:2933599090
European Community (EC) Number:846-747-3
DSSTox Substance ID:DTXSID70597432
Wikidata:Q82492973
Mol file:138538-42-8.mol

Synonyms:6-Methylpyrimidine-4-carboxylic acid;138538-42-8;4-PYRIMIDINECARBOXYLIC ACID, 6-METHYL-;4-Pyrimidinecarboxylic acid, 6-methyl- (9CI);MFCD09881198;SCHEMBL1671322;DTXSID70597432;YSRGRWJKRYESQW-UHFFFAOYSA-N;6-Methylpyrimidine-4-carboxylicacid;6-methyl-pyrimidine-4-carboxylic acid;AKOS012040020;CCG-321241;DS-6446;PB20450;SY042182;DB-359660;CS-0045929;EN300-82517;P10833;A886221;F1967-2301;Z1013699410

Suppliers and Price of 6-Methylpyrimidine-4-carboxylic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
6-Methylpyrimidine-4-CarboxylicAcid
1g
$ 45.00

Matrix Scientific
6-Methylpyrimidine-4-carboxylicacid 97.0%
1g
$ 594.00

Chemenu
6-methylpyrimidine-4-carboxylicacid 97%
10g
$ 1398.00

Chemenu
6-methylpyrimidine-4-carboxylicacid 97%
5g
$ 839.00

Apolloscientific
6-Methylpyrimidine-4-carboxylicacid 95%
250mg
$ 225.00

Total 10 raw suppliers

Chemical Property of 6-Methylpyrimidine-4-carboxylic acid

Chemical Property:

PSA：63.08000
LogP:0.48320
Storage Temp.:2-8°C
XLogP3:0.5
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:1
Exact Mass:138.042927438
Heavy Atom Count:10
Complexity:138

Purity/Quality:

99%, ^*data from raw suppliers

6-Methylpyrimidine-4-CarboxylicAcid ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=CC(=NC=N1)C(=O)O

Technology Process of 6-Methylpyrimidine-4-carboxylic acid

There total 4 articles about 6-Methylpyrimidine-4-carboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.0%

: 148149-29-5
ethyl 6-methylpyrimidine-4-carboxylate

: 138538-42-8
6-methylpyrimidine-4-carboxylic acid

Guidance literature:: With potassium hydroxide; In ethanol; at 20 ℃; for 2h;
DOI:10.1016/j.tet.2019.05.005

Reference yield:

: 1558-17-4
4,6-dimethylpyrimidine

: 138538-42-8
6-methylpyrimidine-4-carboxylic acid

Guidance literature:: With potassium permanganate; water;

Reference yield:

: ethyl 4-methoxy-2-oxo-3-pentenoate

: 138538-42-8
6-methylpyrimidine-4-carboxylic acid

Guidance literature:: Multi-step reaction with 2 steps

1: potassium carbonate / acetonitrile / 2 h / 70 °C / Reflux

2: potassium hydroxide / ethanol / 2 h / 20 °C

With potassium carbonate; potassium hydroxide; In ethanol; acetonitrile;
DOI:10.1016/j.tet.2019.05.005