Welcome to LookChem.com Sign In|Join Free

CAS

  • or

1558-17-4

Post Buying Request

1558-17-4 Suppliers

Recommended suppliersmore

  • Product
  • FOB Price
  • Min.Order
  • Supply Ability
  • Supplier
  • Contact Supplier

1558-17-4 Usage

Chemical Properties

clear yellowish liquid after melting

Uses

4,6-Dimethylpyrimidine is used to produce (6-methyl-pyrimidin-4-yl)-pyruvic acid ethyl ester. It is used as pharmaceutical intermediate. It is also used in agrochemical and dyestuff field.

Synthesis Reference(s)

Journal of Heterocyclic Chemistry, 19, p. 373, 1982 DOI: 10.1002/jhet.5570190231

Check Digit Verification of cas no

The CAS Registry Mumber 1558-17-4 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 1,5,5 and 8 respectively; the second part has 2 digits, 1 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 1558-17:
(6*1)+(5*5)+(4*5)+(3*8)+(2*1)+(1*7)=84
84 % 10 = 4
So 1558-17-4 is a valid CAS Registry Number.
InChI:InChI=1/C6H8N2/c1-5-3-6(2)8-4-7-5/h3-4H,1-2H3

1558-17-4 Well-known Company Product Price

  • Brand
  • (Code)Product description
  • CAS number
  • Packaging
  • Price
  • Detail
  • Alfa Aesar

  • (A10302)  4,6-Dimethylpyrimidine, 94%   

  • 1558-17-4

  • 1g

  • 532.0CNY

  • Detail
  • Alfa Aesar

  • (A10302)  4,6-Dimethylpyrimidine, 94%   

  • 1558-17-4

  • 5g

  • 1377.0CNY

  • Detail
  • Aldrich

  • (D183202)  4,6-Dimethylpyrimidine  ≥93%, technical grade

  • 1558-17-4

  • D183202-10G

  • 2,479.23CNY

  • Detail

1558-17-4SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 10, 2017

Revision Date: Aug 10, 2017

1.Identification

1.1 GHS Product identifier

Product name 4,6-Dimethylpyrimidine

1.2 Other means of identification

Product number -
Other names 4,6-?Dimethylpyrimidine

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:1558-17-4 SDS

1558-17-4Synthetic route

2,5-dimethyl-pyrazine
123-32-0

2,5-dimethyl-pyrazine

A

2,5-dimethylpyrimidine
22868-76-4

2,5-dimethylpyrimidine

B

4,6-dimethylpyrimidine
1558-17-4

4,6-dimethylpyrimidine

Conditions
ConditionsYield
under 1 - 1.5 Torr; for 0.0833333h; Irradiation;A 72%
B 26%
N-Benzyl-4,6-dimethylpyrimidinium bromide
82619-54-3

N-Benzyl-4,6-dimethylpyrimidinium bromide

4,6-dimethylpyrimidine
1558-17-4

4,6-dimethylpyrimidine

Conditions
ConditionsYield
With ammonia at -33℃; for 2h; Product distribution; Mechanism;65%
N-(p-nitrophenyl)-4,6-dimethylpyrimidinium bromide
82619-55-4

N-(p-nitrophenyl)-4,6-dimethylpyrimidinium bromide

A

4,6-dimethylpyrimidine
1558-17-4

4,6-dimethylpyrimidine

B

p-nitrobenzylamine
7409-30-5

p-nitrobenzylamine

Conditions
ConditionsYield
With ammonia at -33℃; for 2h; Product distribution; Mechanism;A 65%
B 37%
2,5-dimethylpyrimidine
22868-76-4

2,5-dimethylpyrimidine

A

2,5-dimethyl-pyrazine
123-32-0

2,5-dimethyl-pyrazine

B

4,6-dimethylpyrimidine
1558-17-4

4,6-dimethylpyrimidine

Conditions
ConditionsYield
under 1 - 1.5 Torr; for 0.0833333h; Irradiation;A 62%
B 31%
2-chloro-4,6-dimethylpyrimidine
4472-44-0

2-chloro-4,6-dimethylpyrimidine

4,6-dimethylpyrimidine
1558-17-4

4,6-dimethylpyrimidine

Conditions
ConditionsYield
With water; zinc
With palladium on activated charcoal; sodium acetate; acetic acid Hydrogenation;
With palladium on activated charcoal; ethanol; sodium acetate under 5148.6 Torr; Hydrogenation;
Multi-step reaction with 2 steps
1: N2H4 * H2O
2: aqueous CuSO4
View Scheme
methanol
67-56-1

methanol

4,6-dimethyl-2-pyrimidinecarbonitrile
22126-16-5

4,6-dimethyl-2-pyrimidinecarbonitrile

A

4,6-dimethylpyrimidine
1558-17-4

4,6-dimethylpyrimidine

B

methyl 4,6-dimethylpyrimidine-2-carboxylate
27427-89-0

methyl 4,6-dimethylpyrimidine-2-carboxylate

Conditions
ConditionsYield
With hydrogenchloride; water
4,6-dimethyl-2-pyrimidinecarboxylic acid
60420-76-0

4,6-dimethyl-2-pyrimidinecarboxylic acid

4,6-dimethylpyrimidine
1558-17-4

4,6-dimethylpyrimidine

Conditions
ConditionsYield
Destillieren;
2-hydrazino-4,6-dimethylpyrimidine
23906-13-0

2-hydrazino-4,6-dimethylpyrimidine

4,6-dimethylpyrimidine
1558-17-4

4,6-dimethylpyrimidine

Conditions
ConditionsYield
With copper(II) sulfate
4,6-dimethylpyrimidine-2(1H)-thione hydrochloride
62501-45-5

4,6-dimethylpyrimidine-2(1H)-thione hydrochloride

4,6-dimethylpyrimidine
1558-17-4

4,6-dimethylpyrimidine

Conditions
ConditionsYield
With hydrogenchloride; nickel
acetylacetone
123-54-6

acetylacetone

4,6-dimethylpyrimidine
1558-17-4

4,6-dimethylpyrimidine

Conditions
ConditionsYield
With water at 180 - 190℃;
at 220 - 240℃;
PYRIMIDINE
289-95-2

PYRIMIDINE

tert.-butylhydroperoxide
75-91-2

tert.-butylhydroperoxide

A

4-Methylpyrimidine
3438-46-8

4-Methylpyrimidine

B

2-methylpyrimidine
5053-43-0

2-methylpyrimidine

C

2,4-dimethylpyrimidine
14331-54-5

2,4-dimethylpyrimidine

D

4,6-dimethylpyrimidine
1558-17-4

4,6-dimethylpyrimidine

E

2,4,6-trimethylpyrimidine
22114-27-8

2,4,6-trimethylpyrimidine

Conditions
ConditionsYield
With sulfuric acid; iron(II) sulfate In water at 20 - 25℃; for 0.5h; Product distribution; various radical source ratios, varipus conversion and produts yield;
PYRIMIDINE
289-95-2

PYRIMIDINE

acetic acid
64-19-7

acetic acid

A

4-Methylpyrimidine
3438-46-8

4-Methylpyrimidine

B

2-methylpyrimidine
5053-43-0

2-methylpyrimidine

C

2,4-dimethylpyrimidine
14331-54-5

2,4-dimethylpyrimidine

D

4,6-dimethylpyrimidine
1558-17-4

4,6-dimethylpyrimidine

Conditions
ConditionsYield
With ammonium thiosulphate; silver nitrate at 90℃; for 2h; Product distribution; various radical source ratios, varipus conversion and produts yield;
PYRIMIDINE
289-95-2

PYRIMIDINE

dimethyl sulfoxide
67-68-5

dimethyl sulfoxide

A

4-Methylpyrimidine
3438-46-8

4-Methylpyrimidine

B

2-methylpyrimidine
5053-43-0

2-methylpyrimidine

C

2,4-dimethylpyrimidine
14331-54-5

2,4-dimethylpyrimidine

D

4,6-dimethylpyrimidine
1558-17-4

4,6-dimethylpyrimidine

E

2,4,6-trimethylpyrimidine
22114-27-8

2,4,6-trimethylpyrimidine

Conditions
ConditionsYield
With sulfuric acid; dihydrogen peroxide; iron(II) sulfate In water Product distribution; Ambient temperature; various radical source ratios, varipus conversion and produts yield;
4-Methylpyrimidine
3438-46-8

4-Methylpyrimidine

tert.-butylhydroperoxide
75-91-2

tert.-butylhydroperoxide

A

2,4-dimethylpyrimidine
14331-54-5

2,4-dimethylpyrimidine

B

4,6-dimethylpyrimidine
1558-17-4

4,6-dimethylpyrimidine

Conditions
ConditionsYield
With sulfuric acid; iron(II) sulfate In water at 20 - 25℃; for 0.5h;A 32 % Turnov.
B 65 % Turnov.
2-methylpyrimidine
5053-43-0

2-methylpyrimidine

tert.-butylhydroperoxide
75-91-2

tert.-butylhydroperoxide

A

2,4-dimethylpyrimidine
14331-54-5

2,4-dimethylpyrimidine

B

4,6-dimethylpyrimidine
1558-17-4

4,6-dimethylpyrimidine

C

2,4,6-trimethylpyrimidine
22114-27-8

2,4,6-trimethylpyrimidine

Conditions
ConditionsYield
With sulfuric acid; iron(II) sulfate In water at 20 - 25℃; for 0.5h;A 32 % Turnov.
B 65 % Turnov.
C 3 % Turnov.
acetylacetone
123-54-6

acetylacetone

formamidine
463-52-5

formamidine

4,6-dimethylpyrimidine
1558-17-4

4,6-dimethylpyrimidine

Conditions
ConditionsYield
In dimethylsulfoxide-d6 at 22 - 28℃; Mechanism; determined of intermedier by 13C nmr;
4.6-dimethyl-pyrimidine-carboxylic acid-(2)

4.6-dimethyl-pyrimidine-carboxylic acid-(2)

4,6-dimethylpyrimidine
1558-17-4

4,6-dimethylpyrimidine

Conditions
ConditionsYield
bei der Destillation;
2-chloro-4,6-dimethylpyrimidine
4472-44-0

2-chloro-4,6-dimethylpyrimidine

water
7732-18-5

water

zinc dust

zinc dust

4,6-dimethylpyrimidine
1558-17-4

4,6-dimethylpyrimidine

(4,6-dimethylpyrimid-2′-yl)-trimethylammonium chloride
77767-94-3

(4,6-dimethylpyrimid-2′-yl)-trimethylammonium chloride

4,6-dimethylpyrimidine
1558-17-4

4,6-dimethylpyrimidine

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: acetamide
2: HCl; water
View Scheme
4,6-dimethylpyrimidine
1558-17-4

4,6-dimethylpyrimidine

4-Fluorobenzyl bromide
459-46-1

4-Fluorobenzyl bromide

4-[2-(4-fluorophenyl)ethyl]-6-methylpyrimidine
329983-94-0

4-[2-(4-fluorophenyl)ethyl]-6-methylpyrimidine

Conditions
ConditionsYield
Stage #1: 4,6-dimethylpyrimidine With n-butyllithium In tetrahydrofuran; hexane at -78℃;
Stage #2: 4-Fluorobenzyl bromide In tetrahydrofuran; hexane at -78℃; Further stages.;
100%
4,6-dimethylpyrimidine
1558-17-4

4,6-dimethylpyrimidine

benzyl bromide
100-39-0

benzyl bromide

4-methyl-6-phenethylpyrimidine
329983-86-0

4-methyl-6-phenethylpyrimidine

Conditions
ConditionsYield
Stage #1: 4,6-dimethylpyrimidine With n-butyllithium In tetrahydrofuran; hexane at -78℃;
Stage #2: benzyl bromide In tetrahydrofuran; hexane at -78℃; Further stages.;
99%
With n-butyllithium; ammonium chloride In tetrahydrofuran
4,6-dimethylpyrimidine
1558-17-4

4,6-dimethylpyrimidine

carbon dioxide
124-38-9

carbon dioxide

lithium (6-methylpyrimidin-4-yl)acetate

lithium (6-methylpyrimidin-4-yl)acetate

Conditions
ConditionsYield
Stage #1: 4,6-dimethylpyrimidine With n-butyllithium In tetrahydrofuran at -78℃; for 0.333333h;
Stage #2: carbon dioxide In tetrahydrofuran at -78 - 15℃; for 1h;
97%
Stage #1: 4,6-dimethylpyrimidine With n-butyllithium In tetrahydrofuran; hexane at -78℃; for 0.333333h;
Stage #2: carbon dioxide In tetrahydrofuran; hexane at 15℃; for 1h;
97%
Stage #1: 4,6-dimethylpyrimidine With [2,2]bipyridinyl; n-butyllithium In tetrahydrofuran; hexane at -78℃; for 0.333333h; Inert atmosphere;
Stage #2: carbon dioxide In tetrahydrofuran; hexane at -78 - 20℃; for 1.25h;
4,6-dimethylpyrimidine
1558-17-4

4,6-dimethylpyrimidine

N-methylpyrrole aldehyde
1192-58-1

N-methylpyrrole aldehyde

(E,E)-4,6-bis[2-(1-methyl-1H-pyrrol-2-yl)vinyl]pyrimidine
1154426-21-7

(E,E)-4,6-bis[2-(1-methyl-1H-pyrrol-2-yl)vinyl]pyrimidine

Conditions
ConditionsYield
With sodium hydroxide; Aliquat 336 In water for 1h; Reflux;95%
With Aliquat 336; sodium hydroxide at 20 - 110℃; for 4h;40%
4,6-dimethylpyrimidine
1558-17-4

4,6-dimethylpyrimidine

potassium tetrachloroaurate(III) dihydrate

potassium tetrachloroaurate(III) dihydrate

Au(chloride)3(4,6-dimethylpyrimidine)
1233385-56-2

Au(chloride)3(4,6-dimethylpyrimidine)

Conditions
ConditionsYield
In methanol; water dropwise addn. of soln. of N compd. in methanol to aq. soln. of Au compd.; filtration, washing with water, drying under vacuum;95%
4,6-dimethylpyrimidine
1558-17-4

4,6-dimethylpyrimidine

methanol
67-56-1

methanol

(4,6-dimethylpyrimidin-2-yl)methanol
54198-72-0

(4,6-dimethylpyrimidin-2-yl)methanol

Conditions
ConditionsYield
With ammonium peroxydisulfate; sulfuric acid In water for 5h; Heating;93%
thiophene-2-carbaldehyde
98-03-3

thiophene-2-carbaldehyde

4,6-dimethylpyrimidine
1558-17-4

4,6-dimethylpyrimidine

(E,E)-4,6-bis[2-(thiophen-2-yl)vinyl]pyrimidine
1154426-26-2

(E,E)-4,6-bis[2-(thiophen-2-yl)vinyl]pyrimidine

Conditions
ConditionsYield
With sodium hydroxide; Aliquat 336 In water for 1h; Reflux;93%
3-thiophene carboxaldehyde
498-62-4

3-thiophene carboxaldehyde

4,6-dimethylpyrimidine
1558-17-4

4,6-dimethylpyrimidine

(E,E)-4,6-bis[2-(thiophen-3-yl)vinyl]pyrimidine
1154426-36-4

(E,E)-4,6-bis[2-(thiophen-3-yl)vinyl]pyrimidine

Conditions
ConditionsYield
With sodium hydroxide; Aliquat 336 In water for 1h; Reflux;93%
4,6-dimethylpyrimidine
1558-17-4

4,6-dimethylpyrimidine

4-(piperidin-1-yl)benzaldehyde
10338-57-5

4-(piperidin-1-yl)benzaldehyde

4,6-bis(4-(piperidin-1-yl)styryl)pyrimidine

4,6-bis(4-(piperidin-1-yl)styryl)pyrimidine

Conditions
ConditionsYield
Stage #1: 4,6-dimethylpyrimidine With potassium tert-butylate In N,N-dimethyl-formamide at 80℃; for 0.25h;
Stage #2: 4-(piperidin-1-yl)benzaldehyde In N,N-dimethyl-formamide at 80℃; for 4h;
92%
TETRAHYDROPYRANE
142-68-7

TETRAHYDROPYRANE

4,6-dimethylpyrimidine
1558-17-4

4,6-dimethylpyrimidine

4,6-dimethyl-2-(tetrahydro-2H-pyran-2-yl)pyrimidine

4,6-dimethyl-2-(tetrahydro-2H-pyran-2-yl)pyrimidine

Conditions
ConditionsYield
With sodium persulfate; [4,4’-bis(1,1-dimethylethyl)-2,2’-bipyridine-N1,N1‘]bis [3,5-difluoro-2-[5-(trifluoromethyl)-2-pyridinyl-N]phenyl-C]iridium(III) hexafluorophosphate; trifluoroacetic acid In water; acetonitrile at 23℃; for 8h; Minisci Aromatic Substitution; Inert atmosphere; Irradiation; regioselective reaction;91%
4,6-dimethylpyrimidine
1558-17-4

4,6-dimethylpyrimidine

benzaldehyde
100-52-7

benzaldehyde

(E,E)-4,6-bis-styrylpyrimidine
68763-05-3, 36272-52-3

(E,E)-4,6-bis-styrylpyrimidine

Conditions
ConditionsYield
With sodium hydroxide; tetra(n-butyl)ammonium hydrogensulfate for 1h; Heating;90%
With sodium hydroxide In water for 1h; Reflux;79%
With tetra(n-butyl)ammonium hydrogensulfate; sodium hydroxide In water Reflux;76%
With sodium hydroxide; Aliquat 336 for 1h; Heating;
4,6-dimethylpyrimidine
1558-17-4

4,6-dimethylpyrimidine

4-methoxy-benzaldehyde
123-11-5

4-methoxy-benzaldehyde

4,6-bis[2-(4-methoxyphenyl)ethenyl]pyrimidine

4,6-bis[2-(4-methoxyphenyl)ethenyl]pyrimidine

Conditions
ConditionsYield
With sodium hydroxide; tetra(n-butyl)ammonium hydrogensulfate for 1h; Heating;90%
With sodium hydroxide In water for 2h; Inert atmosphere; Reflux;90%
With sodium hydroxide; Aliquat 336 for 1h; Heating;
4,6-dimethylpyrimidine
1558-17-4

4,6-dimethylpyrimidine

trisilver(I) tris(3,5-bis(trifluoromethyl)pyrazolate)
274249-48-8

trisilver(I) tris(3,5-bis(trifluoromethyl)pyrazolate)

C5HF6N2(1-)*Ag(1+)*C6H8N2

C5HF6N2(1-)*Ag(1+)*C6H8N2

Conditions
ConditionsYield
In toluene at 20℃; for 12h; Inert atmosphere; Schlenk technique;90%
4,6-dimethylpyrimidine
1558-17-4

4,6-dimethylpyrimidine

4-dimethylamino-benzaldehyde
100-10-7

4-dimethylamino-benzaldehyde

4,4′-(1E,1′E)-2,2′-(pyrimidine-4,6-diyl)bis(ethene-2,1-diyl)bis(N,N-dimethylaniline)
1154426-01-3

4,4′-(1E,1′E)-2,2′-(pyrimidine-4,6-diyl)bis(ethene-2,1-diyl)bis(N,N-dimethylaniline)

Conditions
ConditionsYield
Stage #1: 4,6-dimethylpyrimidine With potassium tert-butylate In N,N-dimethyl-formamide at 80℃; for 0.25h;
Stage #2: 4-dimethylamino-benzaldehyde In N,N-dimethyl-formamide at 80℃; for 4h;
89%
With sodium hydroxide; Aliquat 336 In water for 1h; Reflux;77%
With sodium hydroxide In water for 2h; Inert atmosphere; Reflux;77%
With Aliquat 336; sodium hydroxide at 20 - 110℃; for 4h;20%
4,6-dimethylpyrimidine
1558-17-4

4,6-dimethylpyrimidine

4-(4-morpholinyl)benzaldehyde
1204-86-0

4-(4-morpholinyl)benzaldehyde

4,6-bis(4-morpholinostyryl)pyrimidine

4,6-bis(4-morpholinostyryl)pyrimidine

Conditions
ConditionsYield
Stage #1: 4,6-dimethylpyrimidine With potassium tert-butylate In N,N-dimethyl-formamide at 80℃; for 0.25h;
Stage #2: 4-(4-morpholinyl)benzaldehyde In N,N-dimethyl-formamide at 80℃; for 4h;
88%
4,6-dimethylpyrimidine
1558-17-4

4,6-dimethylpyrimidine

Phenanthrene-9-carboxaldehyde
4707-71-5

Phenanthrene-9-carboxaldehyde

(E,E)-4,6-bis[2-(phenanthren-9-yl)vinyl]pyrimidine
1154425-59-8

(E,E)-4,6-bis[2-(phenanthren-9-yl)vinyl]pyrimidine

Conditions
ConditionsYield
With sodium hydroxide; Aliquat 336 In water for 1h; Reflux;86%
4,6-dimethylpyrimidine
1558-17-4

4,6-dimethylpyrimidine

4-(pyrrolidin-1-yl)benzaldehyde
51980-54-2

4-(pyrrolidin-1-yl)benzaldehyde

4,6-bis(4-(pyrrolidin-1-yl)styryl)pyrimidine

4,6-bis(4-(pyrrolidin-1-yl)styryl)pyrimidine

Conditions
ConditionsYield
Stage #1: 4,6-dimethylpyrimidine With potassium tert-butylate In N,N-dimethyl-formamide at 80℃; for 0.25h;
Stage #2: 4-(pyrrolidin-1-yl)benzaldehyde In N,N-dimethyl-formamide at 80℃; for 4h;
86%
4,6-dimethylpyrimidine
1558-17-4

4,6-dimethylpyrimidine

terephthalaldehyde mono(diethylacetal)
81172-89-6

terephthalaldehyde mono(diethylacetal)

4-[2-(4-pyrimidinyl)ethenyl]-4'-[2-(6-pyrimidinyl)ethenyl]benzaldehyde

4-[2-(4-pyrimidinyl)ethenyl]-4'-[2-(6-pyrimidinyl)ethenyl]benzaldehyde

Conditions
ConditionsYield
With sodium hydroxide; Aliquat 336 for 1h; Heating;85%
Stage #1: 4,6-dimethylpyrimidine; terephthalaldehyde mono(diethylacetal) With sodium hydroxide In water for 2h; Heating;
Stage #2: With hydrogenchloride In acetone at 20℃; for 0.0833333h;
71%
4,6-dimethylpyrimidine
1558-17-4

4,6-dimethylpyrimidine

4-[(4-methoxyphenyl)methoxy]benzaldehyde
77182-73-1

4-[(4-methoxyphenyl)methoxy]benzaldehyde

(E,E)-4,6-bis[4'-(4''-methoxybenzyloxy)styryl]pyrimidine
1396036-52-4

(E,E)-4,6-bis[4'-(4''-methoxybenzyloxy)styryl]pyrimidine

Conditions
ConditionsYield
With tetra(n-butyl)ammonium hydrogensulfate; sodium hydroxide In water Reflux;84%
4,6-dimethylpyrimidine
1558-17-4

4,6-dimethylpyrimidine

4-(4-methylpiperazin-1-yl) benzaldehyde
27913-99-1

4-(4-methylpiperazin-1-yl) benzaldehyde

4,6-bis(4-(4-methylpiperazin-1-yl)styryl)pyrimidine

4,6-bis(4-(4-methylpiperazin-1-yl)styryl)pyrimidine

Conditions
ConditionsYield
Stage #1: 4,6-dimethylpyrimidine With potassium tert-butylate In N,N-dimethyl-formamide at 80℃; for 0.25h;
Stage #2: 4-(4-methylpiperazin-1-yl) benzaldehyde In N,N-dimethyl-formamide at 80℃; for 4h;
84%
4,6-dimethylpyrimidine
1558-17-4

4,6-dimethylpyrimidine

2-phenylperimidine
15666-84-9

2-phenylperimidine

6,8-dimethyl-2-phenylbenzo[gh]perimidine

6,8-dimethyl-2-phenylbenzo[gh]perimidine

Conditions
ConditionsYield
With polyphosphoric acid at 250℃;82%
4,6-dimethylpyrimidine
1558-17-4

4,6-dimethylpyrimidine

4-(hexyloxy)benzaldehyde
5736-94-7

4-(hexyloxy)benzaldehyde

(E,E)-4,6-bis(4-hexyloxystyryl)pyrimidine
1154425-13-4

(E,E)-4,6-bis(4-hexyloxystyryl)pyrimidine

Conditions
ConditionsYield
With sodium hydroxide; Aliquat 336 In water for 1h; Reflux;81%
4,6-dimethylpyrimidine
1558-17-4

4,6-dimethylpyrimidine

4-methoxy-3-((4-methoxybenzyl)oxy)benzaldehyde
72785-29-6

4-methoxy-3-((4-methoxybenzyl)oxy)benzaldehyde

(E,E)-4,6-bis[4'-methoxy-3'-(4''-methoxybenzyloxy)styryl]pyrimidine
1236355-55-7

(E,E)-4,6-bis[4'-methoxy-3'-(4''-methoxybenzyloxy)styryl]pyrimidine

Conditions
ConditionsYield
With tetra(n-butyl)ammonium hydrogensulfate; sodium hydroxide In water Reflux;81%
With sodium hydroxide; tetra(n-butyl)ammonium hydrogensulfate In water Reflux;
4,6-dimethylpyrimidine
1558-17-4

4,6-dimethylpyrimidine

3-methoxy 4-((4-methoxybenzyl)oxy)benzaldehyde
129047-38-7

3-methoxy 4-((4-methoxybenzyl)oxy)benzaldehyde

(E,E)-4,6-bis[3'-methoxy-4'-(4''-methoxybenzyloxy)styryl]pyrimidine
1396036-62-6

(E,E)-4,6-bis[3'-methoxy-4'-(4''-methoxybenzyloxy)styryl]pyrimidine

Conditions
ConditionsYield
With tetra(n-butyl)ammonium hydrogensulfate; sodium hydroxide In water Reflux;81%
4,6-dimethylpyrimidine
1558-17-4

4,6-dimethylpyrimidine

terephthalaldehyde mono(diethylacetal)
81172-89-6

terephthalaldehyde mono(diethylacetal)

4,6-bis{2-[4-(diethoxymethyl)phenyl]ethenyl}pyrimidine

4,6-bis{2-[4-(diethoxymethyl)phenyl]ethenyl}pyrimidine

Conditions
ConditionsYield
With sodium hydroxide; tetra(n-butyl)ammonium hydrogensulfate for 1h; Heating;80%
4,6-dimethylpyrimidine
1558-17-4

4,6-dimethylpyrimidine

5-bromo-2-thiophencarboxaldehyde
4701-17-1

5-bromo-2-thiophencarboxaldehyde

(E,E)-4,6-bis[2-(5-bromothiophen-2-yl)vinyl]pyrimidine
1154426-31-9

(E,E)-4,6-bis[2-(5-bromothiophen-2-yl)vinyl]pyrimidine

Conditions
ConditionsYield
With sodium hydroxide; Aliquat 336 In water for 1h; Reflux;78%
4,6-dimethylpyrimidine
1558-17-4

4,6-dimethylpyrimidine

2-methyl-1H-perimidine
5157-10-8

2-methyl-1H-perimidine

2,6,8-trimethylbenzo[gh]perimidine

2,6,8-trimethylbenzo[gh]perimidine

Conditions
ConditionsYield
With polyphosphoric acid at 250℃;78%
4,6-dimethylpyrimidine
1558-17-4

4,6-dimethylpyrimidine

[Rh2(μ-Cl)2(tetrafluorobenzobarrelene)2]

[Rh2(μ-Cl)2(tetrafluorobenzobarrelene)2]

silver perchlorate

silver perchlorate

{Rh(tetrafluorobenzobarrelene)(4,6-dimethylpyrimidine)}(ClO4)

{Rh(tetrafluorobenzobarrelene)(4,6-dimethylpyrimidine)}(ClO4)

Conditions
ConditionsYield
In acetone byproducts: AgCl; acetone soln. of AgClO4 added to suspn. of Rh complex in acetone, stirred for 30 min, filtered off AgCl, added amine ligand to filtrate, stirred for 20 min; concd., added hexane, filtered off, washed with hexane, air-dried, elem. anal.;76%
4,6-dimethylpyrimidine
1558-17-4

4,6-dimethylpyrimidine

[(norbornadiene)rhodium(I)chloride]2
12257-42-0

[(norbornadiene)rhodium(I)chloride]2

{(RhCl(2,5-norbornadiene))2(4,6-dimethylpyrimidine)}
90423-47-5

{(RhCl(2,5-norbornadiene))2(4,6-dimethylpyrimidine)}

Conditions
ConditionsYield
In acetone addn. of amine ligand to suspn. of Rh complex in acetone, soln. stirred for 20 min; concd. in vac., added hexane, filtered off, washed with hexane, air-dried, elem. anal.;76%
4,6-dimethylpyrimidine
1558-17-4

4,6-dimethylpyrimidine

3-(4-Methoxybenzyloxy)benzaldehyde
108781-14-2

3-(4-Methoxybenzyloxy)benzaldehyde

(E,E)-4,6-bis[3'-(4''-methoxybenzyloxy)styryl]pyrimidine
1396036-57-9

(E,E)-4,6-bis[3'-(4''-methoxybenzyloxy)styryl]pyrimidine

Conditions
ConditionsYield
With tetra(n-butyl)ammonium hydrogensulfate; sodium hydroxide In water Reflux;76%

1558-17-4Relevant articles and documents

Vapor phase phototransposition chemistry of dimethylpyrazines and dimethylpyrimidines

Pavlik, James W.,Vongakorn, Tharinee,Kebede, Naod

, p. 216 - 228 (2017/11/17)

Based on their phototransposition chemistry, the three dimethylpyrazines and four dimethylpyrimidines can be arranged into two groups. 2,5-Dimethylpyrazine, 2,5-dimethylpyrimidine, and 4,6-dimethylpyrimidine constitute a photochemical triad. Irradiation of any one member of the triad in the vapor phase results in the formation of the other two members. The other four isomers, 2,6-dimethylpyrazine, 2,3-dimethylpyrazine, 2,4- dimethylpyrimidine, and 4,5-dimethylpyrimidine constitute a photochemical tetrad. Irradiation of any one member results in the formation of the other three. In addition, 2,4-dimethylpyrimidine and 2,6-dimethylpyrazine also photoisomerize to 3,6-dimethylpyridazine. Irradiation of the last in the vapor state resulted in the four members of the tetrad.

POLAR EFFECTS IN THE HOMOLYTIC METHYLATION OF PYRIMIDINE: ORIENTATION AND POLYSUBSTITUTION

Giordano, Claudio,Minisci, Francesco,Tortelli, Vito,Vismara, Elena

, p. 293 - 296 (2007/10/02)

The homolytic methylation of pyrimidine in aqueous solution has been investigated with three different radical sources: tBuOOH-Fe(2+), MeCO2H-S2O8(2-)-Ag(1+), and MeSOMe-H2O2-Fe(2+).This last reagent, used for the first time in homolytic aromatic substitution, turned out to be the most efficient.The orientation of mono- and poly-methylated derivatives is discussed on the basis of polar effects.

Post a RFQ

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

1

What can I do for you?
Get Best Price

Get Best Price for 1558-17-4