Ethyl 8-chloro-4-oxo-4H-quinolizine-3-carboxylate

Base Information

Chemical Name:Ethyl 8-chloro-4-oxo-4H-quinolizine-3-carboxylate
CAS No.:139161-20-9
Molecular Formula:C12H10ClNO3
Molecular Weight:251.67
Hs Code.:2918300090
DSSTox Substance ID:DTXSID30391377
Wikidata:Q82188800
Mol file:139161-20-9.mol

Synonyms:139161-20-9;Ethyl 8-chloro-4-oxo-4H-quinolizine-3-carboxylate;Ethyl 8-Chloro-4-oxo-4H-quinolizine-3-carboxlate;ethyl 8-chloro-4-oxoquinolizine-3-carboxylate;SCHEMBL6755336;DTXSID30391377;YJSYYXAPXKCOMG-UHFFFAOYSA-N;FT-0668205;Ethyl 8-chloro-4H-quinolizin-4-one-3-carboxylate;J-007245

Suppliers and Price of Ethyl 8-chloro-4-oxo-4H-quinolizine-3-carboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Usbiological
Ethyl 8-Chloro-4-oxo-4H-quinolizine-3-carboxlate
10mg
$ 418.00

TRC
Ethyl8-Chloro-4-oxo-4H-quinolizine-3-carboxlate
10mg
$ 120.00

Crysdot
Ethyl8-chloro-4-oxo-4H-quinolizine-3-carboxylate 95+%
1g
$ 1786.00

American Custom Chemicals Corporation
ETHYL-8-CHLORO-4-OXO-4H-QUINOLIZINE-3-CARBOXLATE 95.00%
100MG
$ 1686.30

American Custom Chemicals Corporation
ETHYL-8-CHLORO-4-OXO-4H-QUINOLIZINE-3-CARBOXLATE 95.00%
10MG
$ 716.10

Total 9 raw suppliers

Chemical Property of Ethyl 8-chloro-4-oxo-4H-quinolizine-3-carboxylate

Chemical Property:

Vapor Pressure:2.92E-07mmHg at 25°C
Melting Point:161-164°C
Refractive Index:1.616
Boiling Point:420°C at 760 mmHg
Flash Point:207.8°C
PSA：47.78000
Density:1.39g/cm³
LogP:2.12960
Storage Temp.:2-8°C
Solubility.:Chloroform (Slightly), Methanol (Slightly)
XLogP3:2.1
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:3
Exact Mass:251.0349209
Heavy Atom Count:17
Complexity:500

Purity/Quality:

99% ^*data from raw suppliers

Ethyl 8-Chloro-4-oxo-4H-quinolizine-3-carboxlate ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCOC(=O)C1=CC=C2C=C(C=CN2C1=O)Cl

Technology Process of Ethyl 8-chloro-4-oxo-4H-quinolizine-3-carboxylate

There total 2 articles about Ethyl 8-chloro-4-oxo-4H-quinolizine-3-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 66.0%

: 3678-63-5
4-chIoro-2-methylpyridine

: 87-13-8
diethyl 2-ethoxymethylenemalonate

: 139161-20-9
ethyl 8-chloro-4-oxo-4H-quinolizine-3-carboxylate

Guidance literature:: 4-chIoro-2-methylpyridine; With lithium diisopropyl amide; In tetrahydrofuran; n-heptane; at -60 ℃; for 0.5h;

diethyl 2-ethoxymethylenemalonate; In tetrahydrofuran; n-heptane; at -60 - 20 ℃; for 3.5h;