2-Methyl-3-(2-methyl-1,3-oxazol-4-yl)prop-2-enal

Base Information

Chemical Name:2-Methyl-3-(2-methyl-1,3-oxazol-4-yl)prop-2-enal
CAS No.:139630-91-4
Molecular Formula:C8H9NO2
Molecular Weight:151.16
Hs Code.:2934999090
DSSTox Substance ID:DTXSID30698439
Mol file:139630-91-4.mol

Synonyms:DTXSID30698439;2-methyl-3-(2-methyl-1,3-oxazol-4-yl)prop-2-enal

Suppliers and Price of 2-Methyl-3-(2-methyl-1,3-oxazol-4-yl)prop-2-enal

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
2-METHYL-3-[4-METHYL(3,5-OXAZOLYL)]PROP-2-ENAL 95.00%
5MG
$ 505.33

Total 3 raw suppliers

Chemical Property of 2-Methyl-3-(2-methyl-1,3-oxazol-4-yl)prop-2-enal

Chemical Property:

Vapor Pressure:0.01mmHg at 25°C
Refractive Index:1.528
Boiling Point:263.4°Cat760mmHg
Flash Point:113.1°C
PSA：43.10000
Density:1.108g/cm³
LogP:1.58520
XLogP3:1
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:151.063328530
Heavy Atom Count:11
Complexity:177

Purity/Quality:

97% ^*data from raw suppliers

2-METHYL-3-[4-METHYL(3,5-OXAZOLYL)]PROP-2-ENAL 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=NC(=CO1)C=C(C)C=O

Technology Process of 2-Methyl-3-(2-methyl-1,3-oxazol-4-yl)prop-2-enal

There total 9 articles about 2-Methyl-3-(2-methyl-1,3-oxazol-4-yl)prop-2-enal which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

: 24720-64-7
2-(triphenylphosphoranylidene)propionaldehyde

: 113732-84-6
2-methyl-1,3-oxazole-4-carbaldehyde

: 139630-91-4
(E)-2-methyl-3-(2-methyloxazol-4-yl)acrylaldehyde

Guidance literature:: In benzene; at 80 ℃; for 18h; Heating;
DOI:10.1021/ol010193a

Reference yield:

: 85806-67-3
2-methyl-oxazole-4-carboxylic acid methyl ester

: 139630-91-4
(E)-2-methyl-3-(2-methyloxazol-4-yl)acrylaldehyde

Guidance literature:: Multi-step reaction with 3 steps

1: 65 percent / LiAlH₄ / diethyl ether; tetrahydrofuran / 3 h / -78 °C

2: 94 percent / oxalyl chloride; dimethylsulfoxide; triethylamine / CH₂Cl₂ / -60 - 20 °C

3: 91 percent / benzene / 72 h / 20 °C

With lithium aluminium tetrahydride; oxalyl dichloride; dimethyl sulfoxide; triethylamine; In tetrahydrofuran; diethyl ether; dichloromethane; benzene; 2: Swern oxidation / 3: Wittig olefination;
DOI:10.1021/jo034011x

Reference yield:

: 141567-53-5
4-hydroxymethyl-2-methyloxazole

: 139630-91-4
(E)-2-methyl-3-(2-methyloxazol-4-yl)acrylaldehyde

Guidance literature:: Multi-step reaction with 2 steps

1: 94 percent / oxalyl chloride; dimethylsulfoxide; triethylamine / CH₂Cl₂ / -60 - 20 °C

2: 91 percent / benzene / 72 h / 20 °C

With oxalyl dichloride; dimethyl sulfoxide; triethylamine; In dichloromethane; benzene; 1: Swern oxidation / 2: Wittig olefination;
DOI:10.1021/jo034011x