6,9-DIAZA-SPIRO[4.5]DECANE DIHYDROCHLORIDE

Base Information

Chemical Name:6,9-DIAZA-SPIRO[4.5]DECANE DIHYDROCHLORIDE
CAS No.:145122-55-0
Molecular Formula:C8H16 N2 . 2 Cl H
Molecular Weight:0
Hs Code.:2933990090
Mol file:145122-55-0.mol

Synonyms:6,9-Diazaspiro[4.5]decane,dihydrochloride (9CI)

Suppliers and Price of 6,9-DIAZA-SPIRO[4.5]DECANE DIHYDROCHLORIDE

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
6,9-diazaspiro[4.5]decanehydratedihydrochloride
500mg
$ 240.00

TRC
6,9-diazaspiro[4.5]decanehydratedihydrochloride
50mg
$ 45.00

Crysdot
6,9-Diazaspiro[4.5]decanedihydrochloride 95+%
5g
$ 502.00

Chemenu
6,9-Diazaspiro[4.5]decanedihydrochloride 95%
5g
$ 474.00

American Custom Chemicals Corporation
6,9-DIAZA-SPIRO[4.5]DECANE DIHYDROCHLORIDE 95.00%
1G
$ 836.80

Alichem
6,9-Diazaspiro[4.5]decanedihydrochloride
5g
$ 522.21

AK Scientific
6,9-Diaza-spiro[4.5]decanedihydrochloride
1g
$ 245.00

Total 12 raw suppliers

Chemical Property of 6,9-DIAZA-SPIRO[4.5]DECANE DIHYDROCHLORIDE

Chemical Property:

Vapor Pressure:0.000347mmHg at 25°C
Refractive Index: ">
Boiling Point:314.2°Cat760mmHg
Flash Point:143.9°C
PSA：24.06000
Density:g/cm³
LogP:2.75360

Purity/Quality:

97% ^*data from raw suppliers

6,9-diazaspiro[4.5]decanehydratedihydrochloride ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 6,9-DIAZA-SPIRO[4.5]DECANE DIHYDROCHLORIDE

There total 4 articles about 6,9-DIAZA-SPIRO[4.5]DECANE DIHYDROCHLORIDE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 22649-37-2
1-amino-cyclopentanecarboxylic acid ethyl ester hydrochloride

: 145122-55-0
6,9-diazaspiro<4,5>decane dihydrochloride

Guidance literature:: Multi-step reaction with 3 steps

1: 88 percent / NaHCO₃ / tetrahydrofuran; H₂O / 16 h / Ambient temperature

2: 71.4 percent / H₂ / 10percent Pd/C / ethanol / 18 h / 3040 Torr

3: 1.) borane*THF complex 2.) HCl / 1.) THF, 60 deg C, 20 h 2.) methanol, reflux, 2 h

With hydrogenchloride; borane-THF; hydrogen; sodium hydrogencarbonate; palladium on activated charcoal; In tetrahydrofuran; ethanol; water;
DOI:10.1139/v92-171

Reference yield:

: 93948-00-6
1-N-carbobenzyloxyglycylamino-1-ethoxycarbonylcyclopentane

: 145122-55-0
6,9-diazaspiro<4,5>decane dihydrochloride

Guidance literature:: Multi-step reaction with 2 steps

1: 71.4 percent / H₂ / 10percent Pd/C / ethanol / 18 h / 3040 Torr

2: 1.) borane*THF complex 2.) HCl / 1.) THF, 60 deg C, 20 h 2.) methanol, reflux, 2 h

With hydrogenchloride; borane-THF; hydrogen; palladium on activated charcoal; In ethanol;
DOI:10.1139/v92-171

Reference yield:

: 52-52-8
1-amino-1-cyclopentanecarboxylic acid

: 145122-55-0
6,9-diazaspiro<4,5>decane dihydrochloride

Guidance literature:: Multi-step reaction with 4 steps

1: 83 percent / thionyl chloride / 4 h / Heating

2: 88 percent / NaHCO₃ / tetrahydrofuran; H₂O / 16 h / Ambient temperature

3: 71.4 percent / H₂ / 10percent Pd/C / ethanol / 18 h / 3040 Torr

4: 1.) borane*THF complex 2.) HCl / 1.) THF, 60 deg C, 20 h 2.) methanol, reflux, 2 h

With hydrogenchloride; thionyl chloride; borane-THF; hydrogen; sodium hydrogencarbonate; palladium on activated charcoal; In tetrahydrofuran; ethanol; water;
DOI:10.1139/v92-171