3-[4-(2-Aminoethyl)piperazin-1-yl]propan-1-ol

Base Information

Chemical Name:3-[4-(2-Aminoethyl)piperazin-1-yl]propan-1-ol
CAS No.:145708-28-7
Molecular Formula:C₉H₂₁N₃O
Molecular Weight:187.285
Hs Code.:
DSSTox Substance ID:DTXSID60473736
Wikidata:Q82303337
Mol file:145708-28-7.mol

Synonyms:3-[4-(2-aminoethyl)piperazin-1-yl]propan-1-ol;145708-28-7;1-Piperazinepropanol,4-(2-aminoethyl)-(9CI);SCHEMBL9346853;DTXSID60473736;AKOS010933820

Suppliers and Price of 3-[4-(2-Aminoethyl)piperazin-1-yl]propan-1-ol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of 3-[4-(2-Aminoethyl)piperazin-1-yl]propan-1-ol

Chemical Property:

PSA：52.73000
LogP:-0.47880
XLogP3:-1.2
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:5
Exact Mass:187.168462302
Heavy Atom Count:13
Complexity:124

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CN(CCN1CCCO)CCN

Technology Process of 3-[4-(2-Aminoethyl)piperazin-1-yl]propan-1-ol

There total 3 articles about 3-[4-(2-Aminoethyl)piperazin-1-yl]propan-1-ol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

: 156339-58-1
1-(2-acetylaminoethyl)-4-(3-hydroxypropyl)piperazine

: 145708-28-7
1-(2-aminoethyl)-4-(3-hydroxypropyl)piperazine

Guidance literature:: With hydrogenchloride; at 80 ℃; for 4h;
DOI:10.1248/cpb.42.963

Reference yield:

: 5317-32-8
3-(1-piperazinyl)-1-propanol

: 145708-28-7
1-(2-aminoethyl)-4-(3-hydroxypropyl)piperazine

Guidance literature:: Multi-step reaction with 2 steps

1: 34 percent / benzene / 12 h / Heating

2: 91 percent / conc. aq. HCl / 4 h / 80 °C

With hydrogenchloride; In benzene;
DOI:10.1248/cpb.42.963