3-Bromo-5-(bromomethyl)pyridine

Base Information

Chemical Name:3-Bromo-5-(bromomethyl)pyridine
CAS No.:145743-85-7
Molecular Formula:C6H5 Br2 N
Molecular Weight:250.92
Hs Code.:
DSSTox Substance ID:DTXSID00565664
Wikidata:Q82450881
Mol file:145743-85-7.mol

Synonyms:3-BROMO-5-(BROMOMETHYL)PYRIDINE;145743-85-7;3-Bromo-5-bromomethyl pyridine;Pyridine, 3-bromo-5-(bromomethyl)- (9CI);3-Bromo-5-bromomethylpyridine;3-bromo-5(bromomethyl)pyridine;SCHEMBL3183730;3-Bromo-5-bromomethyl-pyridine;5-bromo-3-(bromomethyl)pyridine;DTXSID00565664;AJQDEUJYFUHVHS-UHFFFAOYSA-N;AKOS012019951;Pyridine,3-bromo-5-(bromomethyl)-(9ci);A3173;G11375

Suppliers and Price of 3-Bromo-5-(bromomethyl)pyridine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
3-Bromo-5-bromomethylpyridine
50mg
$ 155.00

TRC
3-Bromo-5-bromomethylpyridine
10mg
$ 45.00

Labseeker
3-bromo-5-(bromomethyl)pyridine 95
10g
$ 1600.00

Labseeker
3-bromo-5-(bromomethyl)pyridine 95
5g
$ 1217.00

Labseeker
3-bromo-5-(bromomethyl)pyridine 95
25g
$ 2200.00

Crysdot
3-Bromo-5-(bromomethyl)pyridine 95%
10g
$ 743.00

Crysdot
3-Bromo-5-(bromomethyl)pyridine 95%
25g
$ 1188.00

Crysdot
3-Bromo-5-(bromomethyl)pyridine 95%
5g
$ 495.00

American Custom Chemicals Corporation
3-BROMO-5-(BROMOMETHYL)PYRIDINE 95.00%
5MG
$ 502.79

Alichem
3-Bromo-5-(bromomethyl)pyridine
500mg
$ 1019.20

Total 12 raw suppliers

Chemical Property of 3-Bromo-5-(bromomethyl)pyridine

Chemical Property:

Vapor Pressure:0.008mmHg at 25°C
Refractive Index:1.613
Boiling Point:277.312ºC at 760 mmHg
PKA:1.97±0.20(Predicted)
Flash Point:121.514ºC
PSA：12.89000
Density:1.955g/cm3
LogP:2.73900
XLogP3:2.1
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:1
Exact Mass:250.87682
Heavy Atom Count:9
Complexity:87.1

Purity/Quality:

97% ^*data from raw suppliers

3-Bromo-5-bromomethylpyridine ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=C(C=NC=C1Br)CBr

Technology Process of 3-Bromo-5-(bromomethyl)pyridine

There total 4 articles about 3-Bromo-5-(bromomethyl)pyridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 69.0%

: 37669-64-0
(5-bromopyridin-3-yl)methanol

: 145743-85-7
5-bromo-3-(bromomethyl)pyridine

Guidance literature:: (5-bromopyridin-3-yl)methanol; With phosphorus tribromide; In dichloromethane; at 0 - 20 ℃; for 2h; Inert atmosphere;

With triethylamine; In dichloromethane; for 1h;

With potassium carbonate; In dichloromethane; water; at 0 ℃; pH=7;

Reference yield:

LiBr powder: LiBr powder

: 37669-64-0
(5-bromopyridin-3-yl)methanol

: 584-08-7
potassium carbonate

: 145743-85-7
5-bromo-3-(bromomethyl)pyridine

Guidance literature:: With pyridine; In tetrahydrofuran; dichloromethane;

Reference yield:

: 20826-04-4
5-bromo-3-pyridinecarboxylic acid

: 145743-85-7
5-bromo-3-(bromomethyl)pyridine

Guidance literature:: Multi-step reaction with 2 steps

1.1: chloroformic acid ethyl ester; triethylamine / tetrahydrofuran / 1 h / 0 - 20 °C / Inert atmosphere

1.2: 20 °C

2.1: phosphorus tribromide / dichloromethane / 2 h / 0 - 20 °C / Inert atmosphere

2.2: 1 h

2.3: 0 °C / pH 7

With chloroformic acid ethyl ester; phosphorus tribromide; triethylamine; In tetrahydrofuran; dichloromethane;