2(3H)-Furanone,dihydro-3,4-dimethyl-5-(1-methylethyl)-,(3alpha,4alpha,5alpha)-(9CI)

Base Information

Chemical Name:2(3H)-Furanone,dihydro-3,4-dimethyl-5-(1-methylethyl)-,(3alpha,4alpha,5alpha)-(9CI)
CAS No.:146231-63-2
Molecular Formula:C₉H₁₆O₂
Molecular Weight:156.225
Hs Code.:
Mol file:146231-63-2.mol

Synonyms:2(3H)-Furanone,dihydro-3,4-dimethyl-5-(1-methylethyl)-,(3alpha,4alpha,5alpha)-(9CI)

Suppliers and Price of 2(3H)-Furanone,dihydro-3,4-dimethyl-5-(1-methylethyl)-,(3alpha,4alpha,5alpha)-(9CI)

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 2 raw suppliers

Chemical Property of 2(3H)-Furanone,dihydro-3,4-dimethyl-5-(1-methylethyl)-,(3alpha,4alpha,5alpha)-(9CI)

Chemical Property:

PSA：26.30000
LogP:1.84000

Purity/Quality:: 85.0-99.8% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 2(3H)-Furanone,dihydro-3,4-dimethyl-5-(1-methylethyl)-,(3alpha,4alpha,5alpha)-(9CI)

There total 9 articles about 2(3H)-Furanone,dihydro-3,4-dimethyl-5-(1-methylethyl)-,(3alpha,4alpha,5alpha)-(9CI) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

: (3S*,4R*,5R*)-4,5-dihydro-3,4-dimethyl-5-isopropyl-3-(phenylsulfonyl)-2(3H)-furanone

: 121725-92-6,146231-63-2,154968-09-9
(3S*,4S*,5R*)-4,5-dihydro-3,4-dimethyl-5-isopropyl-2(3H)-furanone

Guidance literature:: With disodium hydrogenphosphate; sodium amalgam; In methanol; for 2.5h; Ambient temperature;
DOI:10.1016/S0040-4020(01)80181-2

Reference yield: 68.0%

: (4R,5S)-3-Benzenesulfonyl-5-isopropyl-3,4-dimethyl-dihydro-furan-2-one

: 121725-92-6,146231-63-2,154968-09-9
(3S*,4R*,5R*)-4,5-dihydro-3,4-dimethyl-5-isopropyl-2(3H)-furanone

Guidance literature:: With disodium hydrogenphosphate; sodium amalgam; In methanol; for 2h; Ambient temperature;
DOI:10.1016/S0040-4020(01)80181-2

Reference yield:

: 129083-21-2
(E)-4-methyl-1-(phenylsulfonyl)pent-1-en-3-ol

: 121725-92-6,146231-63-2,154968-09-9
(3S*,4S*,5R*)-4,5-dihydro-3,4-dimethyl-5-isopropyl-2(3H)-furanone

Guidance literature:: Multi-step reaction with 6 steps

1: phosphorus pentoxide / CHCl₃ / 1.5 h / Ambient temperature

2: n-BuLi / hexane; tetrahydrofuran / 1 h / -78 °C

3: 96 percent / CF₃SO₃H / ethanol / 6.5 h / Ambient temperature

4: CH₂Cl₂ / 0.5 h / -20 °C

5: 87 percent / NaH / dimethylformamide / 24 h / 40 °C

6: 92 percent / Na₂HPO₄, 6percent Na(Hg) / methanol / 2.5 h / Ambient temperature

With phosphorus pentaoxide; disodium hydrogenphosphate; n-butyllithium; sodium amalgam; trifluorormethanesulfonic acid; sodium hydride; In tetrahydrofuran; methanol; ethanol; hexane; dichloromethane; chloroform; N,N-dimethyl-formamide;
DOI:10.1016/S0040-4020(01)80181-2