Quinoxaline, 7-methoxy-2-methyl-

Base Information

• Chemical Name: Quinoxaline, 7-methoxy-2-methyl-
• CAS No.: 146294-18-0
• Molecular Formula: C₁₀H₁₀N₂O
• Molecular Weight: 174.202
• Mol file: 146294-18-0.mol

Synonyms:Quinoxaline, 7-methoxy-2-methyl-

Chemical Property of Quinoxaline, 7-methoxy-2-methyl-

Chemical Property:

• PSA: 0.00000
• LogP: 0.00000

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Quinoxaline, 7-methoxy-2-methyl-

There total 11 articles about Quinoxaline, 7-methoxy-2-methyl- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 70.0%

N-(4-methoxy-2-nitrophenyl)-N-(prop-2-yn-1-yl)acetamide → 7-methoxy-2-methylquinoxaline (146294-18-0)

Guidance literature:

N-(4-methoxy-2-nitrophenyl)-N-(prop-2-yn-1-yl)acetamide; With hydrogenchloride; In water; at 90 ℃; for 7h; Inert atmosphere;

With hydrogenchloride; tin(II) chloride hydrate; In water; isopropyl alcohol; Reagent/catalyst; Reflux;

DOI:10.1039/c5ob01532d

Reference yield: 67.0%

8-amino-7-methoxy-2-methylquinoxaline (146294-27-1) → 7-methoxy-2-methylquinoxaline (146294-18-0)

Guidance literature:

With ethanol; sulfuric acid; sodium nitrite; at 0 - 60 ℃; for 0.166667h;

Reference yield:

4-methoxy-1,2-phenylenediamine (102-51-2) + 2-oxopropanal (78-98-8) → 6-methoxy-2-methylquinoxaline (146294-17-9) + 7-methoxy-2-methylquinoxaline (146294-18-0)

Guidance literature:

With hydrogenchloride; In methanol; for 0.166667h; Title compound not separated from byproducts; Heating;

upstream raw materials:

8-amino-7-methoxy-2-methylquinoxaline

4-methoxy-1,2-phenylenediamine

2-oxopropanal

5-methoxy-2,1,3-benzoselenadiazole

Refernces

• 1、 -. "Method for synthesizing quinoxaline compound under visible light induced iron catalysis condition". Paragraph 0277-0281. . Retrieved 2021/07/10.
• 2、 Aichhorn, Stefan,Himmelsbach, Markus,Sch?fberger, Wolfgang. "Synthesis of quinoxalines or quinolin-8-amines from N-propargyl aniline derivatives employing tin and indium chlorides". . p. 9373 - 9380. Retrieved 2015/09/15.