N-BOC-2-(3-TRIFLUOROMETHYL-PHENYL)-DL-GLYCINE

Base Information

Chemical Name:N-BOC-2-(3-TRIFLUOROMETHYL-PHENYL)-DL-GLYCINE
CAS No.:146621-92-3
Molecular Formula:C14H16F3NO4
Molecular Weight:319.281
Hs Code.:2924299090
Mol file:146621-92-3.mol

Synonyms:N-Boc-2-(3-trifluoromethylphenyl)glycine;N-Boc-2-(3-trifluoromethyl-phenyl)-DL-glycine;[(tert-Butoxycarbonyl)amino][3-(trifluoromethyl)phenyl]acetic acid;

Suppliers and Price of N-BOC-2-(3-TRIFLUOROMETHYL-PHENYL)-DL-GLYCINE

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
N-Boc-2-(3-Trifluoromethyl-phenyl)-DL-glycine
50mg
$ 65.00

Crysdot
N-Boc-2-(3-trifluoromethylphenyl)-DL-glycine 97%
5g
$ 327.00

Chemenu
N-Boc-2-[3-(trifluoromethyl)phenyl]-DL-glycine 97%
1g
$ 112.00

Chemenu
N-Boc-2-[3-(trifluoromethyl)phenyl]-DL-glycine 97%
5g
$ 309.00

American Custom Chemicals Corporation
N-BOC-2-(3-TRIFLUOROMETHYL-PHENYL)-DL-GLYCINE 95.00%
1G
$ 403.20

Ambeed
N-Boc-2-(3-trifluoromethylphenyl)-DL-glycine 97%
250mg
$ 38.00

Ambeed
N-Boc-2-(3-trifluoromethylphenyl)-DL-glycine 97%
1g
$ 75.00

Alichem
N-Boc-2-(3-trifluoromethylphenyl)-DL-glycine
5g
$ 323.40

Alichem
N-Boc-2-(3-trifluoromethylphenyl)-DL-glycine
25g
$ 1224.30

AK Scientific
[(Tert-butoxycarbonyl)amino][3-(trifluoromethyl)phenyl]aceticacid
250mg
$ 82.00

Total 15 raw suppliers

Chemical Property of N-BOC-2-(3-TRIFLUOROMETHYL-PHENYL)-DL-GLYCINE

Chemical Property:

Vapor Pressure:4.59E-07mmHg at 25°C
Refractive Index:1.487
Boiling Point:398.5 °C at 760 mmHg
PKA:3.36±0.10(Predicted)
Flash Point:194.8 °C
PSA：75.63000
Density:1.297 g/cm³
LogP:3.74670
Storage Temp.:2-8°C

Purity/Quality:

97% ^*data from raw suppliers

N-Boc-2-(3-Trifluoromethyl-phenyl)-DL-glycine ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of N-BOC-2-(3-TRIFLUOROMETHYL-PHENYL)-DL-GLYCINE

There total 3 articles about N-BOC-2-(3-TRIFLUOROMETHYL-PHENYL)-DL-GLYCINE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 24424-99-5
di-tert-butyl dicarbonate

: 242475-26-9,1228548-29-5
2-amino-2-(3-(trifluoromethyl)phenyl)acetic acid

: 146621-92-3
2-{[(tert-butoxy)carbonyl]amino}-2-[3-(trifluoromethyl)phenyl]acetic acid

Guidance literature:: With sodium hydroxide; In tert-butyl alcohol; for 24h; Ambient temperature;
DOI:10.1021/jm00055a002

Reference yield:

: 82425-18-1
[(E)-Hydroxyimino]-(3-trifluoromethyl-phenyl)-acetic acid

: 146621-92-3
2-{[(tert-butoxy)carbonyl]amino}-2-[3-(trifluoromethyl)phenyl]acetic acid

Guidance literature:: Multi-step reaction with 2 steps

1: H₂, conc aq. HCl / 5percent Pd/C / ethanol / 6 h / 760 Torr / Ambient temperature

2: 2N aq. NaOH / 2-methyl-propan-2-ol / 24 h / Ambient temperature

With hydrogenchloride; sodium hydroxide; hydrogen; palladium on activated charcoal; In ethanol; tert-butyl alcohol;
DOI:10.1021/jm00055a002

Reference yield:

: 2338-76-3
3-trifluoromethylphenylacetonitrile

: 146621-92-3
2-{[(tert-butoxy)carbonyl]amino}-2-[3-(trifluoromethyl)phenyl]acetic acid

Guidance literature:: Multi-step reaction with 3 steps

1: isobutyl nitrite, aq. KOH / methanol / 26 h / 50 - 90 °C

2: H₂, conc aq. HCl / 5percent Pd/C / ethanol / 6 h / 760 Torr / Ambient temperature

3: 2N aq. NaOH / 2-methyl-propan-2-ol / 24 h / Ambient temperature

With hydrogenchloride; potassium hydroxide; sodium hydroxide; nitrous acid isobutyl ester; hydrogen; palladium on activated charcoal; In methanol; ethanol; tert-butyl alcohol;
DOI:10.1021/jm00055a002