3-(2-Chloroethyl)-7-methoxy-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one

Base Information

• Chemical Name: 3-(2-Chloroethyl)-7-methoxy-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one
• CAS No.: 147662-99-5
• Molecular Formula: C₁₂H₁₃ClN₂O₂
• Molecular Weight: 252.7
• DSSTox Substance ID: DTXSID60593029
• Wikidata: Q82487414
• Mol file: 147662-99-5.mol

Synonyms:3-(2-Chloroethyl)-7-methoxy-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one;147662-99-5;3-(2-chloroethyl)-7-methoxy-2-methylpyrido[1,2-a]pyrimidin-4-one;FZSZMRUSKSYCGS-UHFFFAOYSA-N;SCHEMBL7378650;DTXSID60593029;DB-303758;J-008381;3-(2-chloroethyl)-7-methoxy-2-methyl-4H-pyrido-[1,2-a]pyrimidin-4-one;3-(2-chloroethyl)-7-methoxy-2-methyl-4H-pyrido[1,2-a]-pyrimidin-4-one

Chemical Property of 3-(2-Chloroethyl)-7-methoxy-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one

Chemical Property:

• Boiling Point: 387.6±52.0 °C(Predicted)
• PKA: 2.83±0.70(Predicted)
• PSA: 43.60000
• Density: 1.29±0.1 g/cm3(Predicted)
• LogP: 1.79280
• Storage Temp.: Refrigerator
• Solubility.: Chloroform, Methanol
• XLogP3: 1
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 3
• Exact Mass: 252.0665554
• Heavy Atom Count: 17
• Complexity: 475

Purity/Quality:

99% ^*data from raw suppliers

3-(2-Chloroethyl)-7-methoxy-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: CC1=C(C(=O)N2C=C(C=CC2=N1)OC)CCCl
• Uses: 3-(2-Chloroethyl)-7-methoxy-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one has long-acting antipsychotic properties useful in the treatment of warm-blooded animals. The compound has long-acting antipsychotic properties useful in the treatment of warm-blooded animals.

Technology Process of 3-(2-Chloroethyl)-7-methoxy-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one

There total 1 articles about 3-(2-Chloroethyl)-7-methoxy-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

3-acetyl-2-oxo-4,5-dihydrofuran (517-23-7,594837-91-9,98634-97-0,313643-49-1) + 2-amino-5-methoxypyridine (10167-97-2) + toluene (108-88-3,15644-74-3,16713-13-6) → 3-(2-chloroethyl)-7-methoxy-2-methyl-4H-pyrido-[1,2-a]pyrimidin-4-one (147662-99-5)

Guidance literature:

With ammonium hydroxide; trichlorophosphate; In hexane; ethyl acetate;

upstream raw materials:

3-acetyl-2-oxo-4,5-dihydrofuran

2-amino-5-methoxypyridine

toluene