1-BROMO-4-CHLORO-2-IODOBENZENE

Base Information

• Chemical Name: 1-BROMO-4-CHLORO-2-IODOBENZENE
• CAS No.: 148836-41-3
• Molecular Formula: C6H3 Br Cl I
• Molecular Weight: 317.351
• Hs Code.: 2903999090
• Mol file: 148836-41-3.mol

Synonyms:1-BROMO-4-CHLORO-2-IODOBENZENE

Chemical Property of 1-BROMO-4-CHLORO-2-IODOBENZENE

Chemical Property:

• Melting Point: 32-33℃
• Boiling Point: 279℃
• Flash Point: 123℃
• PSA: 0.00000
• Density: 2.272
• LogP: 3.70710
• Storage Temp.: Refrigerated.

Purity/Quality:

98%,99%, ^*data from raw suppliers

1-Bromo-4-chloro-2-iodobenzene ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 1-BROMO-4-CHLORO-2-IODOBENZENE

There total 4 articles about 1-BROMO-4-CHLORO-2-IODOBENZENE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

→ 1-bromo-4-chloro-2-iodo-benzene (148836-41-3)

Guidance literature:

With hydrogenchloride; sodium nitrite; In water; at 0 - 5 ℃; for 1h;

With potassium iodide; In water; at 50 ℃; for 24h;

Reference yield: 66.0%

2-bromo-5-chloroaniline (823-57-4) → 1-bromo-4-chloro-2-iodo-benzene (148836-41-3)

Guidance literature:

2-bromo-5-chloroaniline; With hydrogenchloride; sodium nitrite; In water; at -10 - 0 ℃; for 1h;

With potassium iodide; In water; at 0 ℃; for 1h;

Reference yield:

p-chloro-o-iodoaniline (63069-48-7) → 1-bromo-4-chloro-2-iodo-benzene (148836-41-3)

Guidance literature:

With tert.-butylnitrite; copper(ll) bromide; In acetonitrile; for 1h; Product distribution / selectivity;

upstream raw materials:

2-bromo-5-chloroaniline

p-chloro-o-iodoaniline

2-chloro-5-bromonitrobenzene

Downstream raw materials:

6-chloro-3-methyl-1H-indole

1-bromo-4-chloro-2-(3,3,3-triethoxyprop-1-ynyl)benzene

N-(2-bromo-5-chlorophenyl)-2-phenylnaphthalen-1-amine

Refernces

• 1、 -. "ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME". Paragraph 0143-0145. . Retrieved 2016/10/10.
• 2、 Jensen, Thomas,Pedersen, Henrik,Bang-Andersen, Benny,Madsen, Robert,Jorgensen, Morten. "Palladium-catalyzed aryl amination-heck cyclization cascade: A one-flask approach to 3-substituted indoles". . p. 888 - 890. Retrieved 2008/09/20.