1-[4-(4-Hydroxyphenyl)piperidin-1-yl]ethan-1-one

Base Information

Chemical Name:1-[4-(4-Hydroxyphenyl)piperidin-1-yl]ethan-1-one
CAS No.:149354-13-2
Molecular Formula:C13H17 N O2
Molecular Weight:219.283
Hs Code.:
DSSTox Substance ID:DTXSID40598552
Wikidata:Q82494322
Mol file:149354-13-2.mol

Synonyms:149354-13-2;1-[4-(4-hydroxyphenyl)piperidin-1-yl]ethan-1-one;1-(4-(4-Hydroxyphenyl)piperidin-1-yl)ethanone;1-ACETYL-4-(4-HYDROXYPHENYL)PIPERIDINEKETOCONAZOLE;1-[4-(4-HYDROXYPHENYL)PIPERIDIN-1-YL]ETHANONE;1-(4-(4-Hydroxyphenyl)piperidin-1-yl)ethan-1-one;1-ACETYL-4-(4-HYDROXYPHENYL)PIPERIDINE;SCHEMBL7277302;DTXSID40598552;MFCD10566692;AKOS009132693;HL-0758;DB-131765;CS-0239049;EN300-204778

Suppliers and Price of 1-[4-(4-Hydroxyphenyl)piperidin-1-yl]ethan-1-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
1-[4-(4-Hydroxyphenyl)piperidin-1-yl]ethan-1-one
50mg
$ 175.00

Matrix Scientific
1-[4-(4-Hydroxyphenyl)piperidin-1-yl]ethan-1-one >90%
5g
$ 3997.00

Matrix Scientific
1-[4-(4-Hydroxyphenyl)piperidin-1-yl]ethan-1-one >90%
1g
$ 889.00

Matrix Scientific
1-[4-(4-Hydroxyphenyl)piperidin-1-yl]ethan-1-one >90%
500mg
$ 657.00

American Custom Chemicals Corporation
1-ACETYL-4-(4-HYDROXYPHENYL)PIPERIDINE 95.00%
5MG
$ 505.22

Total 4 raw suppliers

Chemical Property of 1-[4-(4-Hydroxyphenyl)piperidin-1-yl]ethan-1-one

Chemical Property:

Boiling Point:415.3±45.0 °C(Predicted)
PKA:10.15±0.30(Predicted)
PSA：40.54000
Density:1.145±0.06 g/cm3(Predicted)
LogP:2.05600
XLogP3:1.6
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:1
Exact Mass:219.125928785
Heavy Atom Count:16
Complexity:238

Purity/Quality:

97% ^*data from raw suppliers

1-[4-(4-Hydroxyphenyl)piperidin-1-yl]ethan-1-one ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(=O)N1CCC(CC1)C2=CC=C(C=C2)O

Technology Process of 1-[4-(4-Hydroxyphenyl)piperidin-1-yl]ethan-1-one

There total 3 articles about 1-[4-(4-Hydroxyphenyl)piperidin-1-yl]ethan-1-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 149354-15-4
4-(1-acetylpiperidin-4-yl)phenyl acetate

: 149354-13-2
1-(4-(4-hydroxyphenyl)piperidin-1-yl)ethan-1-one

Guidance literature:: With water; potassium hydroxide; In 1,4-dioxane; at 20 ℃; for 4h;

Reference yield:

: 62614-84-0
4-(4-hydroxyphenyl)-1,2,3,6-tetrahydropiperidine

: 149354-13-2
1-(4-(4-hydroxyphenyl)piperidin-1-yl)ethan-1-one

Guidance literature:: Multi-step reaction with 2 steps

1: potassium carbonate / water; 1,4-dioxane / 2 h / 20 °C

2: water; potassium hydroxide / 1,4-dioxane / 4 h / 20 °C

With water; potassium carbonate; potassium hydroxide; In 1,4-dioxane; water;