aztreonam

Base Information

Chemical Name:aztreonam
CAS No.:149496-40-2
Molecular Formula:C₁₃H₁₇N₅O₈S₂
Molecular Weight:435.439
Hs Code.:
Mol file:149496-40-2.mol

Synonyms:Propanoicacid,2-[[[1-(2-amino-4-thiazolyl)-2-[(2-methyl-4-oxo-1-sulfo-3-azetidinyl)amino]-2-oxoethylidene]amino]oxy]-2-methyl-,[2a,3b(Z)]-

Suppliers and Price of aztreonam

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 1 raw suppliers

Chemical Property of aztreonam

Chemical Property:

Purity/Quality:: 95% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

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Technology Process of aztreonam

There total 36 articles about aztreonam which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.9%

: 80082-65-1
(3S-trans)-3-Amino-4-methyl-2-oxo-1-azetidinesulfonic acid

: 89604-92-2,158183-05-2
(Z)-2-<<<1-(2-amino-4-thiazolyl)-2-<(2-benzothiazolyl)thio>-2-oxoethylidene>amino>oxy>-2-methyl propanoic acid 1,1-dimethylethyl ester

: 78110-38-0,80951-91-3,149496-40-2,99341-02-3,85506-30-5
azthreonam

Guidance literature:: (3S-trans)-3-Amino-4-methyl-2-oxo-1-azetidinesulfonic acid; (Z)-2-<<<1-(2-amino-4-thiazolyl)-2-<(2-benzothiazolyl)thio>-2-oxoethylidene>amino>oxy>-2-methyl propanoic acid 1,1-dimethylethyl ester; With pyridine; In acetonitrile; at -5 ℃; for 4h;

With nitric acid; at 35 ℃; for 2h; pH=1; Solvent; Reagent/catalyst; Temperature;

Reference yield: 81.0%

: 139714-28-6
(Z)-2-[[[1-(2-amino-4-thiazolyl)-2-(3-oxido-1H-benzotriazol-1-yl)-2-oxoethylidene]amino]oxy]-2-methylpropanoic acid methanesulfonate (1:1) salt

: 80082-65-1
(3S-trans)-3-Amino-4-methyl-2-oxo-1-azetidinesulfonic acid

: 78110-38-0,80951-91-3,149496-40-2,99341-02-3,85506-30-5
azthreonam

Guidance literature:: (Z)-2-[[[1-(2-amino-4-thiazolyl)-2-(3-oxido-1H-benzotriazol-1-yl)-2-oxoethylidene]amino]oxy]-2-methylpropanoic acid methanesulfonate (1:1) salt; (3S-trans)-3-Amino-4-methyl-2-oxo-1-azetidinesulfonic acid; With triethylamine; In ethanol; water; at -6 - -3 ℃; for 3h;

With hydrogenchloride; In ethanol; water; at -3 - 0 ℃;
DOI:10.1021/op025572d