80082-65-1

Basic information

• Product Name: (2S-trans)-3-Amino-2-methyl-4-oxoazetidine-1-sulphonic acid
• Synonyms: (3S-TRANS)-3-AMINO-4-METHYL-2-OXO-1-AZETINESULFONIC ACID;(2S, 3S)-3-Amino-2-methyl-4-oxoazetidine-1-sulfonic acid;SQ-26771;(2S,3S)-3-azanyl-2-methyl-4-oxo-azetidine-1-sulfonic acid;(3S,4S)-3-amino-2-keto-4-methyl-azetidine-1-sulfonic acid;(2R,3S)-3-Amino-2-me;(2S)-3-aMino-2-Methyl-4-oxoazetidine-1-sulfonic acid;(2R,3S)-3-aMino-2-Methyl-4-oxoazetidine-1-sulfonic acid
• CAS NO: 80082-65-1
• Molecular Formula: C₄H₈N₂O₄S
• Molecular Weight: 180.18
• EINECS: 279-393-8
• Product Categories: AZTREONAM;(intermediate of aztreonam);(intermediate of azetronam);Miscellaneous Reagents;Chiral Reagents;Intermediates & Fine Chemicals;Pharmaceuticals;Amines
• Mol File: 80082-65-1.mol
• Article Data: 15

Chemical Properties

• Melting Point: 206-211°C
• Appearance: /
• Density: 1.75 g/cm³
• Refractive Index: 1.627
• Storage Temp.: -20°C Freezer
• Solubility: Water
• PKA: -0.94±0.40(Predicted)
• CAS DataBase Reference: (2S-trans)-3-Amino-2-methyl-4-oxoazetidine-1-sulphonic acid(CAS DataBase Reference)
• NIST Chemistry Reference: (2S-trans)-3-Amino-2-methyl-4-oxoazetidine-1-sulphonic acid(80082-65-1)
• EPA Substance Registry System: (2S-trans)-3-Amino-2-methyl-4-oxoazetidine-1-sulphonic acid(80082-65-1)

Safety Data

• Hazardous Substances Data: 80082-65-1(Hazardous Substances Data)

Usage

Chemical Properties

White Solid

Uses

Different sources of media describe the Uses of 80082-65-1 differently. You can refer to the following data:
1. (2S-trans)-3-Amino-2-methyl-4-oxoazetidine-1-sulphonic acid is an aztreonam intermediate.
2. A useful intermediate in the preparation of ?Lactams

InChI:InChI=1/C4H8N2O4S/c1-2-3(5)4(7)6(2)11(8,9)10/h2-3H,5H2,1H3,(H,8,9,10)/t2-,3-/m0/s1

Synthetic route

(3S)-trans-3-<(tert-butoxycarbonyl)amino>-4-methyl-2-oxoazetidine-1-sulfonic acid tetra-n-butylammonium salt (80082-60-6) → (3S-trans)-3-Amino-4-methyl-2-oxo-1-azetidinesulfonic acid (80082-65-1)

Conditions	Yield
With formic acid for 4.5h; Ambient temperature;	93%
With formic acid for 5h;	70%
With formic acid for 5h; Ambient temperature;	56%

(3S-trans)-2-Oxo-3-[[(phenylmethoxy)carbonyl]amino]-4-methyl-1-azetidinesulfonic acid,tetrabutylammonium salt (80082-62-8) → (3S-trans)-3-Amino-4-methyl-2-oxo-1-azetidinesulfonic acid (80082-65-1)

Conditions	Yield
With hydrogen; palladium on activated charcoal In ethanol	50%

tetrabutylammonium (3S,4S)-3-phenylacetamido-4-methyl-2-oxoazetidine-1-sulfonate (80082-64-0) → (3S-trans)-3-Amino-4-methyl-2-oxo-1-azetidinesulfonic acid (80082-65-1)

Conditions	Yield
With pyridine; phosgene In dichloromethane at 0℃; for 41h;

(3S,4R)-3-benzyloxycarbonylamino-4-methyl-2-oxoazetidine-1-sulphonic acid sodium salt (115887-91-7) → (3S-trans)-3-Amino-4-methyl-2-oxo-1-azetidinesulfonic acid (80082-65-1)

Conditions	Yield
With hydrogen; palladium on activated charcoal In methanol; water for 2h; Ambient temperature;
With nitrogen; palladium In methanol; water
With hydrogenchloride; palladium on activated charcoal; hydrogen In methanol; water for 2h; pH=6.8 - 7;
Stage #1: (3S,4R)-3-benzyloxycarbonylamino-4-methyl-2-oxoazetidine-1-sulphonic acid sodium salt With 5%-palladium/activated carbon; hydrogen In methanol at 15℃; for 4h; Large scale; Stage #2: With hydrogenchloride In methanol; water at 0℃; for 6h; Large scale;

(3S,trans)-4-methyl-3-triphenylmethylamino-2-azetidinone (88144-19-8) → (3S-trans)-3-Amino-4-methyl-2-oxo-1-azetidinesulfonic acid (80082-65-1)

Conditions	Yield
Yield given. Multistep reaction;

C34H69N3O6S → (3S-trans)-3-Amino-4-methyl-2-oxo-1-azetidinesulfonic acid (80082-65-1)

Conditions	Yield
With formic acid at 35 - 40℃; for 4.5h; Inert atmosphere;	12.7 g

C12H27N*C13H14N2O6S → (3S-trans)-3-Amino-4-methyl-2-oxo-1-azetidinesulfonic acid (80082-65-1)

Conditions	Yield
With ammonia; lithium at -40℃; for 0.5h;	56 g

C10H19N2O9S2(1-)*Na(1+) → (3S-trans)-3-Amino-4-methyl-2-oxo-1-azetidinesulfonic acid (80082-65-1)

Conditions	Yield
Stage #1: C10H19N2O9S2(1-)*Na(1+) at 45℃; for 1.5h; Stage #2: With sulfuric acid at 30℃; for 6h;	60 g

tetra(n-butyl)ammonium hydroxide (2052-49-5) + N-(benzyloxycarbonyl)succinimide (75315-63-8) + (3S-trans)-3-Amino-4-methyl-2-oxo-1-azetidinesulfonic acid (80082-65-1) → (3S-trans)-2-Oxo-3-[[(phenylmethoxy)carbonyl]amino]-4-methyl-1-azetidinesulfonic acid,tetrabutylammonium salt (80082-62-8)

Conditions	Yield
Stage #1: N-(benzyloxycarbonyl)succinimide; (3S-trans)-3-Amino-4-methyl-2-oxo-1-azetidinesulfonic acid With triethylamine In ethanol; water at 25℃; for 16h; Stage #2: tetra(n-butyl)ammonium hydroxide In water	94%

N-(Benzyloxycarbonyloxy)succinimide (13139-17-8) + tetra(n-butyl)ammonium hydroxide (2052-49-5) + (3S-trans)-3-Amino-4-methyl-2-oxo-1-azetidinesulfonic acid (80082-65-1) → (3S-trans)-2-Oxo-3-[[(phenylmethoxy)carbonyl]amino]-4-methyl-1-azetidinesulfonic acid,tetrabutylammonium salt (80082-62-8)

Conditions	Yield
Stage #1: N-(Benzyloxycarbonyloxy)succinimide; (3S-trans)-3-Amino-4-methyl-2-oxo-1-azetidinesulfonic acid With triethylamine In ethanol; water at 20℃; for 16h; Stage #2: tetra(n-butyl)ammonium hydroxide In water	94%

(3S-trans)-3-Amino-4-methyl-2-oxo-1-azetidinesulfonic acid (80082-65-1) + (E)-α-(3-Chloroisoxazol-5-yl)-α-methoxyiminoacetic acid (147742-76-5) → sodium (3S,4S)-3-<(E)-(3-chloroisoxazol-5-yl)(methoxyimino)acetylamino>-4-methyl-2-oxoazetidine-1-sulfonate

Conditions	Yield
With ion exchange column (Na form); benzotriazol-1-ol; triethylamine; dicyclohexyl-carbodiimide 1.) DMF, 3 d, 2.) H2O, CH3OH;	91%

(isoxazol-3-yl)acetic acid (57612-86-9) + (3S-trans)-3-Amino-4-methyl-2-oxo-1-azetidinesulfonic acid (80082-65-1) → sodium (3S,4S)-3-<(isoxazol-3-yl)acetylamino>-4-methyl-2-oxoazetidine-1-sulfonate

Conditions	Yield
With ion exchange column (Na form); benzotriazol-1-ol; triethylamine; dicyclohexyl-carbodiimide 1.) DMF, 3 d, 2.) H2O, CH3OH;	87%

(3S-trans)-3-Amino-4-methyl-2-oxo-1-azetidinesulfonic acid (80082-65-1) + 3-chloro-5-isoxazolecarboxylic acid chloride (104164-45-6) → sodium (3S,4S)-3-<(3-chloroisoxazol-5-yl)carbonylamino>-4-methyl-2-oxoazetidine-1-sulfonate

Conditions	Yield
With ion exchange column (Na form); triethylamine; dicyclohexyl-carbodiimide 1.) DMF, 0 to 5 deg C, 1 h, 2.) H2O;	87%

(3S-trans)-3-Amino-4-methyl-2-oxo-1-azetidinesulfonic acid (80082-65-1) + (Z)-2-<<<1-(2-amino-4-thiazolyl)-2-<(2-benzothiazolyl)thio>-2-oxoethylidene>amino>oxy>-2-methyl propanoic acid 1,1-dimethylethyl ester (89604-92-2) → azthreonam (78110-38-0)

Conditions	Yield
Stage #1: (3S-trans)-3-Amino-4-methyl-2-oxo-1-azetidinesulfonic acid; (Z)-2-<<<1-(2-amino-4-thiazolyl)-2-<(2-benzothiazolyl)thio>-2-oxoethylidene>amino>oxy>-2-methyl propanoic acid 1,1-dimethylethyl ester With pyridine In acetonitrile at -5℃; for 4h; Stage #2: With nitric acid at 35℃; for 2h; pH=1; Solvent; Reagent/catalyst; Temperature;	86.9%

(3S-trans)-3-Amino-4-methyl-2-oxo-1-azetidinesulfonic acid (80082-65-1) + (Z)-2-(((1,5-bis(benzhydryloxy)-4-oxo-1,4-dihydropyridin-2-yl)methoxy)imino)-2-(2-(tritylamino)thiazol-4-yl)acetic acid (114875-61-5) → (3S)-trans-3-[[2-(2-tritylamino)thiazol-4-yl]-(Z)-2-{(1,5-dibenzhydryloxy-4-pyridon-2-ylmethoxy)imino}acetamido]-4-methyl-2-oxoazetidine-1-sulfonic acid (404824-78-8)

Conditions	Yield
Stage #1: (3S-trans)-3-Amino-4-methyl-2-oxo-1-azetidinesulfonic acid; (Z)-2-(((1,5-bis(benzhydryloxy)-4-oxo-1,4-dihydropyridin-2-yl)methoxy)imino)-2-(2-(tritylamino)thiazol-4-yl)acetic acid With benzotriazol-1-ol; dicyclohexyl-carbodiimide In DMF (N,N-dimethyl-formamide) at 20℃; for 0.5h; Stage #2: With sodium hydrogencarbonate In DMF (N,N-dimethyl-formamide) at 20℃;	85.9%

(3S-trans)-3-Amino-4-methyl-2-oxo-1-azetidinesulfonic acid (80082-65-1) + triethylamine (121-44-8) + (S)-3-(3,4-Dihydroxy-phenyl)-2-[(4-ethyl-2,3-dioxo-piperazine-1-carbonyl)-amino]-propionic acid 2,5-dioxo-pyrrolidin-1-yl ester → (2S,3S)-3-{(S)-3-(3,4-Dihydroxy-phenyl)-2-[(4-ethyl-2,3-dioxo-piperazine-1-carbonyl)-amino]-propionylamino}-2-methyl-4-oxo-azetidine-1-sulfonic acid; compound with triethyl-amine

Conditions	Yield
In tetrahydrofuran; water at 20℃; for 3h; Acylation;	84%

(3S-trans)-3-Amino-4-methyl-2-oxo-1-azetidinesulfonic acid (80082-65-1) + (5-methoxyisoxazol-3-yl)acetic acid → sodium (3S,4S)-3-<(5-methoxyisoxazol-3-yl)acetylamino>-4-methyl-2-oxoazetidine-1-sulfonate

Conditions	Yield
With ion exchange column (Na form); benzotriazol-1-ol; triethylamine; dicyclohexyl-carbodiimide 1.) DMF, 3 d, 2.) H2O, CH3OH;	82%

(3S-trans)-3-Amino-4-methyl-2-oxo-1-azetidinesulfonic acid (80082-65-1) + (5-chloroisoxazol-3-yl)acetic acid → sodium (3S,4S)-3-<(5-chloroisoxazol-3-yl)acetylamino>-4-methyl-2-oxoazetidine-1-sulfonate

Conditions	Yield
With ion exchange column (Na form); benzotriazol-1-ol; triethylamine; dicyclohexyl-carbodiimide 1.) DMF, 3 d, 2.) H2O, CH3OH;	81%

(Z)-2-[[[1-(2-amino-4-thiazolyl)-2-(3-oxido-1H-benzotriazol-1-yl)-2-oxoethylidene]amino]oxy]-2-methylpropanoic acid methanesulfonate (1:1) salt (139714-28-6) + (3S-trans)-3-Amino-4-methyl-2-oxo-1-azetidinesulfonic acid (80082-65-1) → azthreonam (78110-38-0)

Conditions	Yield
Stage #1: (Z)-2-[[[1-(2-amino-4-thiazolyl)-2-(3-oxido-1H-benzotriazol-1-yl)-2-oxoethylidene]amino]oxy]-2-methylpropanoic acid methanesulfonate (1:1) salt; (3S-trans)-3-Amino-4-methyl-2-oxo-1-azetidinesulfonic acid With triethylamine In ethanol; water at -6 - -3℃; for 3h; Stage #2: With hydrogenchloride In ethanol; water at -3 - 0℃;	81%

C35H38N4O6S2 + (3S-trans)-3-Amino-4-methyl-2-oxo-1-azetidinesulfonic acid (80082-65-1) → (2S,3S)-3-{(S,Z)-5-(tert-butoxycarbonyl)-7-oxo-11-[2-(tritylamino)thiazol-4-yl]- 9-oxa-2-thia-6,10-diazadodec-10-enamido}-2-methyl-4-oxoazetidine-1-sulfonic acid

Conditions	Yield
Stage #1: C35H38N4O6S2 With benzotriazol-1-ol; diisopropyl-carbodiimide In N,N-dimethyl-formamide at 20℃; for 1h; Stage #2: (3S-trans)-3-Amino-4-methyl-2-oxo-1-azetidinesulfonic acid With triethylamine In N,N-dimethyl-formamide at 20℃;	78%

(3S-trans)-3-Amino-4-methyl-2-oxo-1-azetidinesulfonic acid (80082-65-1) + (3-Chloroisoxazol-5-yl)acetic acid (54489-25-7) → sodium (3S,4S)-<(3-chloroisoxazol-5-yl)acetylamino>-4-methyl-2-oxoazetidine-1-sulfonate

Conditions	Yield
With ion exchange column (Na form); triethylamine; dicyclohexyl-carbodiimide 1.) DMF, 24 h, 2.) H2O, CH3OH;	75%

(3S-trans)-3-Amino-4-methyl-2-oxo-1-azetidinesulfonic acid (80082-65-1) + (4-Cyano-5-methylisoxazol-3-yl)acetic acid (93276-75-6) → sodium (3S,4S)-3-<(4-cyano-5-methylisoxazol-3-yl)acetylamino>-4-methyl-2-oxoazetidine-1-sulfonate

Conditions	Yield
With ion exchange column (Na form); triethylamine; dicyclohexyl-carbodiimide 1.) DMF, 24 h, 2.) H2O, CH3OH;	73%

(3S-trans)-3-Amino-4-methyl-2-oxo-1-azetidinesulfonic acid (80082-65-1) + (Z)-α-(3-Chloroisoxazol-5-yl)-α-methoxyiminoacetic acid (147742-85-6) → sodium (3S,4S)-3-<(Z)-(3-chloroisoxazol-5-yl)(methoxyimino)acetylamino>-4-methyl-2-oxoazetidine-1-sulfonate

Conditions	Yield
With ion exchange column (Na form); benzotriazol-1-ol; triethylamine; dicyclohexyl-carbodiimide 1.) DMF, 3 d, 2.) H2O, CH3OH;	62%

(3S-trans)-3-Amino-4-methyl-2-oxo-1-azetidinesulfonic acid (80082-65-1) + triethylamine (121-44-8) + (3,4-dihydroxy-phenylsulfanyl)-acetic acid 2,5-dioxo-pyrrolidin-1-yl ester → (2S,3S)-3-[2-(3,4-Dihydroxy-phenylsulfanyl)-acetylamino]-2-methyl-4-oxo-azetidine-1-sulfonic acid; compound with triethyl-amine

Conditions	Yield
In tetrahydrofuran; water at 20℃; for 3h; Acylation;	59%

(3S-trans)-3-Amino-4-methyl-2-oxo-1-azetidinesulfonic acid (80082-65-1) + α-tert-Butyloxycarbonylamino-α-(3-chloroisoxazol-5-yl)acetic Acid (147742-81-2) → sodium (3S,4S)-3-<(tert-butoxycarbonylamino)(3-chloroisoxazol-5-yl)acetylamino>-4-methyl-2-oxoazetidine-1-sulfonate

Conditions	Yield
With ion exchange column (Na form); benzotriazol-1-ol; triethylamine; dicyclohexyl-carbodiimide 1.) DMF, 3 d, 2.) H2O, CH3OH;	57%

(3S-trans)-3-Amino-4-methyl-2-oxo-1-azetidinesulfonic acid (80082-65-1) + triethylamine (121-44-8) + (2-tert-butoxycarbonylamino-thiazol-4-yl)-[4-(N'-tert-butoxycarbonyl-hydrazinocarbonyl)-benzyloxyimino]-acetic acid [1,2,3]triazolo[4,5-b]pyridin-3-yl ester → trans-3-[(Z)-2-[2-(tert-butoxycarbonylamino)thiazol-4-yl]-2-[[4-[[2-(tert-butoxycarbonyl)hydrazino]carbonyl]benzyloxy]imino]acetamido]-4-methyl-2-oxoazetidine-1-sulfonic acid triethylammonium salt

Conditions	Yield
In N,N-dimethyl-formamide at 20℃; Acylation;	53%

α-methyl-4-chlorobenzylideneaminoxy propionic acid (63564-50-1) + (3S-trans)-3-Amino-4-methyl-2-oxo-1-azetidinesulfonic acid (80082-65-1) → Sodium; (2S,3S)-3-{3-[1-(4-chloro-phenyl)-eth-(E)-ylideneaminooxy]-propionylamino}-2-methyl-4-oxo-azetidine-1-sulfonate (134468-86-3)

Conditions	Yield
With benzotriazol-1-ol; triethylamine; dicyclohexyl-carbodiimide 1) DMF, 30 min, r.t 2) DMF, 18h, r.t.; Yield given. Multistep reaction;

3-(isopropylidenamino)oxy-propanoic acid (103586-55-6) + (3S-trans)-3-Amino-4-methyl-2-oxo-1-azetidinesulfonic acid (80082-65-1) → Sodium; (2S,3S)-3-(3-isopropylideneaminooxy-propionylamino)-2-methyl-4-oxo-azetidine-1-sulfonate (134468-81-8)

Conditions	Yield
With benzotriazol-1-ol; triethylamine; dicyclohexyl-carbodiimide 1) DMF, 30 min, r.t 2) DMF, 18h, r.t.; Yield given. Multistep reaction;

3-(1-Propyl-butylideneaminooxy)-propionic acid (103586-56-7) + (3S-trans)-3-Amino-4-methyl-2-oxo-1-azetidinesulfonic acid (80082-65-1) → Sodium; (2S,3S)-2-methyl-4-oxo-3-[3-(1-propyl-butylideneaminooxy)-propionylamino]-azetidine-1-sulfonate (134468-83-0)

Conditions	Yield
With benzotriazol-1-ol; triethylamine; dicyclohexyl-carbodiimide 1) DMF, 30 min, r.t 2) DMF, 18h, r.t.; Yield given. Multistep reaction;

3-Cyclopentylideneaminooxy-propionic acid (103586-53-4) + (3S-trans)-3-Amino-4-methyl-2-oxo-1-azetidinesulfonic acid (80082-65-1) → Sodium; (2S,3S)-3-(3-cyclopentylideneaminooxy-propionylamino)-2-methyl-4-oxo-azetidine-1-sulfonate (134468-82-9)

Conditions	Yield
With benzotriazol-1-ol; triethylamine; dicyclohexyl-carbodiimide 1) DMF, 30 min, r.t 2) DMF, 18h, r.t.; Yield given. Multistep reaction;

3-[1-Phenyl-eth-(E)-ylideneaminooxy]-propionic acid (103586-52-3) + (3S-trans)-3-Amino-4-methyl-2-oxo-1-azetidinesulfonic acid (80082-65-1) → Sodium; (2S,3S)-2-methyl-4-oxo-3-{3-[1-phenyl-eth-(E)-ylideneaminooxy]-propionylamino}-azetidine-1-sulfonate (134468-85-2)

Conditions	Yield
With benzotriazol-1-ol; triethylamine; dicyclohexyl-carbodiimide 1) DMF, 30 min, r.t 2) DMF, 18h, r.t.; Yield given. Multistep reaction;

(E)-3-<(benzylidene)iminoxy>-(E)-2-(methoxyimino)propionic acid (110596-23-1) + (3S-trans)-3-Amino-4-methyl-2-oxo-1-azetidinesulfonic acid (80082-65-1) → Sodium; (2S,3S)-3-{2-[(E)-methoxyimino]-3-[1-phenyl-meth-(E)-ylideneaminooxy]-propionylamino}-2-methyl-4-oxo-azetidine-1-sulfonate (134468-87-4)

Conditions	Yield
With benzotriazol-1-ol; triethylamine; dicyclohexyl-carbodiimide 1) DMF, 30 min, r.t 2) DMF, 18h, r.t.; Yield given. Multistep reaction;

(E)-3-<<(benzylidene)methyl>iminoxy>-(E)-2-(methoxyimino)propionic acid (110596-24-2) + (3S-trans)-3-Amino-4-methyl-2-oxo-1-azetidinesulfonic acid (80082-65-1) → Sodium; (2S,3S)-3-{2-[(E)-methoxyimino]-3-[1-phenyl-eth-(E)-ylideneaminooxy]-propionylamino}-2-methyl-4-oxo-azetidine-1-sulfonate (134468-91-0)

Conditions	Yield
With benzotriazol-1-ol; triethylamine; dicyclohexyl-carbodiimide 1) DMF, 30 min, r.t 2) DMF, 18h, r.t.; Yield given. Multistep reaction;

Upstream product

• 80082-60-6 (3S)-trans-3-<(tert-butoxycarbonyl)amino>-4-methyl-2-oxoazetidine-1-sulfonic acid tetra-n-butylammonium salt 
• 80082-62-8 (3S-trans)-2-Oxo-3-[[(phenylmethoxy)carbonyl]amino]-4-methyl-1-azetidinesulfonic acid,tetrabutylammonium salt 
• 115887-91-7 cis-3-benzyloxycarbonylamino-4-methyl-2-oxoazetidine-1-sulphonic acid sodium salt 
• 122553-92-8 cis-4-methyl-3-phenylacetylamino-2-oxoazetidine-1-sulphonic acid sodium salt 
• 88144-19-8 (3S,trans)-4-methyl-3-triphenylmethylamino-2-azetidinone 
• 115887-91-7 (3S,4R)-3-benzyloxycarbonylamino-4-methyl-2-oxoazetidine-1-sulphonic acid sodium salt 
• 80082-64-0 tetrabutylammonium (3S,4S)-3-phenylacetamido-4-methyl-2-oxoazetidine-1-sulfonate 

Downstream Products

• 134468-87-4 Sodium; (2S,3S)-3-{2-[(E)-methoxyimino]-3-[1-phenyl-meth-(E)-ylideneaminooxy]-propionylamino}-2-methyl-4-oxo-azetidine-1-sulfonate 
• 134468-91-0 Sodium; (2S,3S)-3-{2-[(E)-methoxyimino]-3-[1-phenyl-eth-(E)-ylideneaminooxy]-propionylamino}-2-methyl-4-oxo-azetidine-1-sulfonate 
• 134468-88-5 Sodium; (2S,3S)-3-{2-[(E)-methoxyimino]-3-[1-(4-methoxy-phenyl)-meth-(E)-ylideneaminooxy]-propionylamino}-2-methyl-4-oxo-azetidine-1-sulfonate 
• 330944-50-8 [3S-[3α(Z),4β]]-3-[[(2-amino-4-thiazolyl)[(1-t-butoxycarbonyl-1-methylethoxy)imino]acetyl]amino]-4-methyl-2-oxo-1-azetidinesulfonic acid 
• 149-30-4 2-Mercaptobenzothiazole 
• 134468-86-3 Sodium; (2S,3S)-3-{3-[1-(4-chloro-phenyl)-eth-(E)-ylideneaminooxy]-propionylamino}-2-methyl-4-oxo-azetidine-1-sulfonate 
• 80082-62-8 (3S-trans)-2-Oxo-3-[[(phenylmethoxy)carbonyl]amino]-4-methyl-1-azetidinesulfonic acid,tetrabutylammonium salt 

Relevant articles and documents

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