D-Galactal cyclic 3,4-carbonate

Base Information

Chemical Name:D-Galactal cyclic 3,4-carbonate
CAS No.:149847-26-7
Molecular Formula:C7H8 O5
Molecular Weight:172.138
Hs Code.:
DSSTox Substance ID:DTXSID20447175
Nikkaji Number:J679.139E
Mol file:149847-26-7.mol

Synonyms:D-Galactal cyclic 3,4-carbonate;149847-26-7;d-galactal cyclic 3 4-carbonate;(3aR,4R,7aR)-4-(hydroxymethyl)-4,7a-dihydro-3aH-[1,3]dioxolo[4,5-c]pyran-2-one;DTXSID20447175;D-Galactal cyclic 3,4-carbonate, AldrichCPR;(1R,2R,6R)-2beta-(Hydroxymethyl)-3,7,9-trioxabicyclo[4.3.0]non-4-en-8-one

Suppliers and Price of D-Galactal cyclic 3,4-carbonate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Sigma-Aldrich
D-Galactal cyclic 3,4-carbonate Aldrich
500mg
$ 239.00

American Custom Chemicals Corporation
D-GALACTAL CYCLIC-3 4-CARBONATE 95.00%
5MG
$ 503.04

Total 2 raw suppliers

Chemical Property of D-Galactal cyclic 3,4-carbonate

Chemical Property:

Melting Point:−34 °C(lit.)
Boiling Point:440.4±45.0 °C(Predicted)
PKA:13.86±0.10(Predicted)
PSA：64.99000
Density:1.408±0.06 g/cm3(Predicted)
LogP:-0.20480
XLogP3:-0.1
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:1
Exact Mass:172.03717335
Heavy Atom Count:12
Complexity:224

Purity/Quality:

95% ^*data from raw suppliers

D-Galactal cyclic 3,4-carbonate Aldrich ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=COC(C2C1OC(=O)O2)CO
Isomeric SMILES:C1=CO[C@@H]([C@H]2[C@@H]1OC(=O)O2)CO

Technology Process of D-Galactal cyclic 3,4-carbonate

There total 6 articles about D-Galactal cyclic 3,4-carbonate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

: 163228-38-4
2,6-anhydro-1-O-[tert-butyl(dimethyl)silyl]-5-deoxy-3,4-O-(oxomethylene)-D-arabino-hex-5-enitol

: 149847-26-7
3,4-o-carbonyl-D-galactal

Guidance literature:: With tetrabutyl ammonium fluoride; In tetrahydrofuran; at 0 - 20 ℃; for 1h; Inert atmosphere;
DOI:10.1021/acs.orglett.8b01506

Reference yield: 90.0%

: 151265-18-8
1,5-anhydro-6-O-(tert-butyldiphenylsilyl)-3,4-O-carbonate-2-deoxy-D-lyxo-hex-1-enopyranose

: 149847-26-7
3,4-o-carbonyl-D-galactal

Guidance literature:: With tetrabutyl ammonium fluoride; In tetrahydrofuran; at 20 ℃; for 6h;
DOI:10.1021/acs.orglett.0c00732

Reference yield:

: 21193-75-9
D-galactal

: 149847-26-7
3,4-o-carbonyl-D-galactal

Guidance literature:: Multi-step reaction with 3 steps

1: 1H-imidazole / N,N-dimethyl-formamide / 10 h / 0 - 20 °C / Inert atmosphere

2: 1H-imidazole / tetrahydrofuran / 10 h / 20 °C / Inert atmosphere

3: tetrabutyl ammonium fluoride / tetrahydrofuran / 1 h / 0 - 20 °C / Inert atmosphere

With 1H-imidazole; tetrabutyl ammonium fluoride; In tetrahydrofuran; N,N-dimethyl-formamide;
DOI:10.1021/acs.orglett.8b01506