[(4E,8S,9S,10E,12S,13R,14S,16R)-13-hydroxy-8,14,19-trimethoxy-4,10,12,16-tetramethyl-3,20,22-trioxo-2-azabicyclo[16.3.1]docosa-1(21),4,10,18-tetraen-9-yl] carbamate

Base Information

Chemical Name:[(4E,8S,9S,10E,12S,13R,14S,16R)-13-hydroxy-8,14,19-trimethoxy-4,10,12,16-tetramethyl-3,20,22-trioxo-2-azabicyclo[16.3.1]docosa-1(21),4,10,18-tetraen-9-yl] carbamate
CAS No.:150270-08-9
Molecular Formula:C₂₉H₄₂N₂O₉
Molecular Weight:562.66
Hs Code.:
ChEMBL ID:CHEMBL340169
DSSTox Substance ID:DTXSID901017663
Nikkaji Number:J696.818J
Wikidata:Q105134214
Mol file:150270-08-9.mol

[(4E,8S,9S,10E,12S,13R,14S,16R)-13-hydroxy-8,14,19-trimethoxy-4,10,12,16-tetramethyl-3,20,22-trioxo-2-azabicyclo[16.3.1]docosa-1(21),4,10,18-tetraen-9-yl] carbamate

Synonyms:CHEMBL340169;DTXSID901017663

Suppliers and Price of [(4E,8S,9S,10E,12S,13R,14S,16R)-13-hydroxy-8,14,19-trimethoxy-4,10,12,16-tetramethyl-3,20,22-trioxo-2-azabicyclo[16.3.1]docosa-1(21),4,10,18-tetraen-9-yl] carbamate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Matrix Scientific
17-Dimethylaminogeldanamycin
50mg
$ 8505.00

Matrix Scientific
17-Dimethylaminogeldanamycin
25mg
$ 4347.00

Matrix Scientific
17-Dimethylaminogeldanamycin
10mg
$ 1890.00

American Custom Chemicals Corporation
17-[2-(DIMETHYLAMINO)ETHYL]AMINO-17-DESMETHOXYGELDANAMYCIN 95.00%
250MG
$ 868.56

American Custom Chemicals Corporation
17-[2-(DIMETHYLAMINO)ETHYL]AMINO-17-DESMETHOXYGELDANAMYCIN 95.00%
50MG
$ 752.14

American Custom Chemicals Corporation
17-[2-(DIMETHYLAMINO)ETHYL]AMINO-17-DESMETHOXYGELDANAMYCIN 95.00%
10MG
$ 650.27

Alfa Aesar
17-DMAG, 98%
1mg
$ 317.00

Total 9 raw suppliers

Chemical Property of [(4E,8S,9S,10E,12S,13R,14S,16R)-13-hydroxy-8,14,19-trimethoxy-4,10,12,16-tetramethyl-3,20,22-trioxo-2-azabicyclo[16.3.1]docosa-1(21),4,10,18-tetraen-9-yl] carbamate

Chemical Property:

Boiling Point:767.9±60.0 °C(Predicted)
PKA:8.88±0.70(Predicted)
PSA：173.75000
Density:1.22±0.1 g/cm3(Predicted)
LogP:3.32450
Storage Temp.:-20°C
Sensitive.:Light Sensitive
Solubility.:Soluble in DMSO (up to 30 mg/ml) or in Ethanol (up to 10 mg/ml).
XLogP3:2
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:9
Rotatable Bond Count:5
Exact Mass:562.28903092
Heavy Atom Count:40
Complexity:1100

Purity/Quality:

97% ^*data from raw suppliers

17-Dimethylaminogeldanamycin ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1CC(C(C(C=C(C(C(CCC=C(C(=O)NC2=CC(=O)C(=C(C1)C2=O)OC)C)OC)OC(=O)N)C)C)O)OC
Isomeric SMILES:C[C@H]1C[C@@H]([C@@H]([C@H](/C=C(/[C@@H]([C@H](CC/C=C(/C(=O)NC2=CC(=O)C(=C(C1)C2=O)OC)\C)OC)OC(=O)N)\C)C)O)OC
Description 17-DMAG (150270-08-9) is an analog of geldanamycin (Cat.# 10-1084) that displays superior pharmacological properties. 17-DMAG inhibits HSP90 and induces apoptosis in a variety of tumor cell lines. Inhibits angiogenesis. Cell Permeable.

Technology Process of [(4E,8S,9S,10E,12S,13R,14S,16R)-13-hydroxy-8,14,19-trimethoxy-4,10,12,16-tetramethyl-3,20,22-trioxo-2-azabicyclo[16.3.1]docosa-1(21),4,10,18-tetraen-9-yl] carbamate

There total 1 articles about [(4E,8S,9S,10E,12S,13R,14S,16R)-13-hydroxy-8,14,19-trimethoxy-4,10,12,16-tetramethyl-3,20,22-trioxo-2-azabicyclo[16.3.1]docosa-1(21),4,10,18-tetraen-9-yl] carbamate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: