H-D-CHA-OH HCL

Base Information

• Chemical Name: H-D-CHA-OH HCL
• CAS No.: 151899-07-9
• Molecular Formula: C9H17 N O2 . Cl H
• Molecular Weight: 207.7
• Hs Code.: 2922499990
• Mol file: 151899-07-9.mol

Synonyms:Cyclohexanepropanoicacid, a-amino-, hydrochloride, (R)-;Cyclohexanepropanoic acid, a-amino-, hydrochloride, (aR)- (9CI); (R)-a-Aminocyclohexanepropionic acid hydrochloride; D-Cyclohexylalaninehydrochloride; b-Cyclohexyl-D-alaninehydrochloride

Chemical Property of H-D-CHA-OH HCL

Chemical Property:

• Boiling Point: 307.1oC at 760 mmHg
• Flash Point: 139.6oC
• PSA: 63.32000
• LogP: 2.87100
• Storage Temp.: Store at RT.

Purity/Quality:

99% ^*data from raw suppliers

(R)-2-Amino-3-cyclohexylpropanoicacidhydrochloride ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of H-D-CHA-OH HCL

There total 1 articles about H-D-CHA-OH HCL which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

D-(R)-phenylalanine (673-06-3,25191-15-5,658-69-5,67675-33-6) → D-cyclohexylalanine hydrochloride (151899-07-9)

Guidance literature:

In hydrogenchloride;

Reference yield: 100.0%

di-tert-butyl dicarbonate (24424-99-5) + D-cyclohexylalanine hydrochloride (151899-07-9) → N-tert-butoxycarbonyl-D-cyclohexylalanine (127095-92-5)

Guidance literature:

With potassium carbonate; In tetrahydrofuran; water; at 20 ℃; pH=10 - 11;

DOI:10.1021/jo034228r

Reference yield: 94.0%

D-cyclohexylalanine hydrochloride (151899-07-9) + benzyl alcohol (100-51-6,185532-71-2) → D-cyclohexylalanine benzyl ester (203732-78-9)

Guidance literature:

With toluene-4-sulfonic acid; In toluene; for 4h; Heating / reflux;

upstream raw materials:

D-(R)-phenylalanine

Downstream raw materials:

methyl (R)-2-amino-3-cyclohexylpropanoate hydrochloride

N-tert-butoxycarbonyl-D-cyclohexylalanine

N-(tert-butyloxycarbonylmethyl)-D-Cha-OMe

(2R)-2-[(tert-butoxycarbonyl)(2-tert-butoxy-2-oxoethyl)amino]-3-cyclohexylpropanoic acid