5-(tert-Butyldimethylsilyl)-1-methyl-1H-imidazole

Base Information

Chemical Name:5-(tert-Butyldimethylsilyl)-1-methyl-1H-imidazole
CAS No.:152120-66-6
Molecular Formula:C₁₀H₂₀N₂Si
Molecular Weight:196.368
Hs Code.:
European Community (EC) Number:633-978-8
DSSTox Substance ID:DTXSID40391000
Mol file:152120-66-6.mol

Synonyms:5-(tert-Butyldimethylsilyl)-1-methyl-1H-imidazole;152120-66-6;tert-butyl-dimethyl-(3-methylimidazol-4-yl)silane;DTXSID40391000;5-(TERT-BUTYLDIMETHYLSILYL)-1-METHYL-1H&;J-008888;5-[tert-Butyl(dimethyl)silyl]-1-methyl-1H-imidazole

Suppliers and Price of 5-(tert-Butyldimethylsilyl)-1-methyl-1H-imidazole

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
5-(TERT-BUTYLDIMETHYLSILYL)-1-METHYL-1H-IMIDAZOLE 95.00%
5G
$ 852.81

Total 7 raw suppliers

Chemical Property of 5-(tert-Butyldimethylsilyl)-1-methyl-1H-imidazole

Chemical Property:

Melting Point:76-78 °C(lit.)
Boiling Point:166-167℃ (4 mmHg)
PKA:7.38±0.22(Predicted)
Flash Point:140oC
PSA：17.82000
Density:0.89±0.1 g/cm3(Predicted)
LogP:2.13560
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:2
Exact Mass:196.139575181
Heavy Atom Count:13
Complexity:184

Purity/Quality:

98%Min ^*data from raw suppliers

5-(TERT-BUTYLDIMETHYLSILYL)-1-METHYL-1H-IMIDAZOLE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:Xi
Statements: 36/37/38
Safety Statements: 26-36

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)(C)[Si](C)(C)C1=CN=CN1C

Technology Process of 5-(tert-Butyldimethylsilyl)-1-methyl-1H-imidazole

There total 2 articles about 5-(tert-Butyldimethylsilyl)-1-methyl-1H-imidazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 191734-24-4
5-Bromo-2-(tert-butyl-dimethyl-silanyl)-1-methyl-1H-imidazole

: 152120-66-6
5-(tert-Butyl-dimethyl-silanyl)-1-methyl-1H-imidazole

Guidance literature:: With n-butyllithium; In tetrahydrofuran; at -70 ℃; for 0.25h; Yield given;
DOI:10.1016/S0040-4039(00)79166-0

Reference yield:

: 18162-48-6
tert-butyldimethylsilyl chloride

: 152120-66-6
5-(tert-Butyl-dimethyl-silanyl)-1-methyl-1H-imidazole

Guidance literature:: Multi-step reaction with 2 steps

1: n-BuLi / tetrahydrofuran / -70 °C

2: n-BuLi / tetrahydrofuran / 0.25 h / -70 °C

With n-butyllithium; In tetrahydrofuran;
DOI:10.1016/S0040-4039(00)79166-0