3,4-Dihydropyrazino[1,2-a]indol-1(2H)-one

Base Information

Chemical Name:3,4-Dihydropyrazino[1,2-a]indol-1(2H)-one
CAS No.:152193-85-6
Molecular Formula:C11H10 N2 O
Molecular Weight:186.213
Hs Code.:2933990090
DSSTox Substance ID:DTXSID30565536
Nikkaji Number:J2.928.070C
Wikidata:Q82450679
Mol file:152193-85-6.mol

Synonyms:3,4-Dihydropyrazino[1,2-a]indol-1(2H)-one;152193-85-6;3,4-DIHYDRO-2H-PYRAZINO[1,2-A]INDOL-1-ONE;MFCD08272112;SCHEMBL1393632;DTXSID30565536;KRRWBFJXTNMYOZ-UHFFFAOYSA-N;CGA19385;AKOS006286017;AB44392;AS-78469;SY069069;CS-0318496;C90411

Suppliers and Price of 3,4-Dihydropyrazino[1,2-a]indol-1(2H)-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
3,4-Dihydro-2H-pyrazino[1,2-a]indol-1-one
100mg
$ 130.00

TRC
3,4-Dihydro-2H-pyrazino[1,2-a]indol-1-one
10mg
$ 45.00

Crysdot
3,4-Dihydropyrazino[1,2-a]indol-1(2H)-one 95+%
5g
$ 628.00

CHESS?
3,4-Dihydro-2H-pyrazino[1,2-a]indol-1-one >98
5 g
$ 78000.00

American Custom Chemicals Corporation
3,4-DIHYDROPYRAZINO-[1,2-A]INDOL-1(2H)-ONE 95.00%
5MG
$ 501.22

Alichem
3,4-Dihydropyrazino[1,2-a]indol-1(2H)-one
1g
$ 400.00

AK Scientific
3,4-Dihydropyrazino[1,2-a]indol-1(2H)-one
5g
$ 1396.00

AccelPharmtech
3,4-dihydro-Pyrazino[1,2-a]indol-1(2H)-one 97.00%
25G
$ 4320.00

AccelPharmtech
3,4-dihydro-Pyrazino[1,2-a]indol-1(2H)-one 97.00%
5G
$ 2330.00

AccelPharmtech
3,4-dihydro-Pyrazino[1,2-a]indol-1(2H)-one 97.00%
1G
$ 2070.00

Total 4 raw suppliers

Chemical Property of 3,4-Dihydropyrazino[1,2-a]indol-1(2H)-one

Chemical Property:

Melting Point:197-198 °C
Boiling Point:492.6±24.0 °C(Predicted)
PKA:15.54±0.20(Predicted)
PSA：34.03000
Density:1.36±0.1 g/cm3(Predicted)
LogP:1.71350
Storage Temp.:2-8°C
XLogP3:1.3
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:0
Exact Mass:186.079312947
Heavy Atom Count:14
Complexity:254

Purity/Quality:

98%min ^*data from raw suppliers

3,4-Dihydro-2H-pyrazino[1,2-a]indol-1-one ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CN2C3=CC=CC=C3C=C2C(=O)N1

Technology Process of 3,4-Dihydropyrazino[1,2-a]indol-1(2H)-one

There total 9 articles about 3,4-Dihydropyrazino[1,2-a]indol-1(2H)-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

: C₁₃H₁₆N₂O₂*C₂HF₃O₂

: 152193-85-6
4-oxo-1,2,3,4-tetrahydropyrazino<1,2-a>indole

Guidance literature:: With water; sodium hydrogencarbonate; In tetrahydrofuran; at 60 ℃; for 16h;

Reference yield: 90.0%

: 1670-84-4
1H-indole-2-carboxamide

: diphenyl(vinyl)sulfonium trifluoromethanesulfonate

: 152193-85-6
4-oxo-1,2,3,4-tetrahydropyrazino<1,2-a>indole

Guidance literature:: 1H-indole-2-carboxamide; With potassium hydroxide; In dichloromethane; at 0 ℃; for 0.166667h; Inert atmosphere;

diphenyl(vinyl)sulfonium trifluoromethanesulfonate; In dichloromethane; at 0 - 20 ℃; Inert atmosphere;
DOI:10.1039/c0cc03823g

Reference yield: 76.0%

: 1174914-87-4
methyl 1-(cyanomethyl)-1H-indole-2-carboxylate

: 152193-85-6
4-oxo-1,2,3,4-tetrahydropyrazino<1,2-a>indole

Guidance literature:: methyl 1-(cyanomethyl)-1H-indole-2-carboxylate; With hydrogenchloride; palladium 10% on activated carbon; hydrogen; In methanol; at 20 ℃; for 24h; under 18.7519 Torr;

With ammonia; In dichloromethane; water; for 1.33333h; pH=> 10; Inert atmosphere;
DOI:10.1016/j.bmc.2009.04.068