5-METHYL-2-THIENYLCARBONYL BENZOIC ACID

Base Information

• Chemical Name: 5-METHYL-2-THIENYLCARBONYL BENZOIC ACID
• CAS No.: 152567-82-3
• Molecular Formula: C13H10O3S
• Molecular Weight: 246.287
• Mol file: 152567-82-3.mol

Synonyms:2-[(5-Methylthiophen-2-yl)carbonyl]benzoic acid;5-Methyl-2-thienylcarbonyl benzoic acid;2-[(5-Methyl-2-thienyl)carbonyl]benzoic acid;

Chemical Property of 5-METHYL-2-THIENYLCARBONYL BENZOIC ACID

Chemical Property:

• Vapor Pressure: 1.13E-09mmHg at 25°C
• Refractive Index: 1.63
• Boiling Point: 470.9 °C at 760 mmHg
• Flash Point: 238.6 °C
• PSA: 82.61000
• Density: 1.325 g/cm³
• LogP: 2.98570

Purity/Quality:

98%min ^*data from raw suppliers

2-(5-Methylthiophene-2-carbonyl)benzoicacid 97% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 5-METHYL-2-THIENYLCARBONYL BENZOIC ACID

There total 3 articles about 5-METHYL-2-THIENYLCARBONYL BENZOIC ACID which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

2-Methylthiophene (554-14-3) + phthalic anhydride (85-44-9) → 2-(5'-methyl-2'-thenoyl)benzoic acid (152567-82-3)

Guidance literature:

With aluminium trichloride; In 1,2-dichloro-ethane; at 40 ℃; for 2h;

DOI:10.1055/s-2002-20033

Reference yield:

2-bromobenzoic-acid (88-65-3) → 2-(5'-methyl-2'-thenoyl)benzoic acid (152567-82-3)

Guidance literature:

2-bromobenzoic-acid; With n-butyllithium; In tetrahydrofuran; at -78 ℃; for 0.5h;

5-methyl-2-thiophenyl carboxylic ester; In tetrahydrofuran; at -78 ℃;

DOI:10.5012/bkcs.2012.33.7.2389

Reference yield:

phthalic anhydride (85-44-9) → 2-(5'-methyl-2'-thenoyl)benzoic acid (152567-82-3)

Guidance literature:

With diethyl ether; methoxybenzene;

DOI:10.1021/jo01139a007

upstream raw materials:

2-Methylthiophene

phthalic anhydride

2-bromobenzoic-acid

Downstream raw materials:

C₂₉H₃₂N₄O₂S

2-(5-methyl-2-thenyl)phenylacetic acid

2-(5-methyl-2-thenyl)benzyl bromide

2-(5-methyl-2-thenyl)benzyl alcohol