(R)-Tert-butyl 2,2-dimethyl-4-(2-oxoethyl)oxazolidine-3-carboxylate

Base Information

Chemical Name:(R)-Tert-butyl 2,2-dimethyl-4-(2-oxoethyl)oxazolidine-3-carboxylate
CAS No.:153053-19-1
Molecular Formula:C₁₂H₂₁NO₄
Molecular Weight:243.303
Hs Code.:2934999090
DSSTox Substance ID:DTXSID00444788
Nikkaji Number:J923.521C
Wikidata:Q82263054
Mol file:153053-19-1.mol

Synonyms:153053-19-1;(R)-TERT-BUTYL 2,2-DIMETHYL-4-(2-OXOETHYL)OXAZOLIDINE-3-CARBOXYLATE;Tert-butyl (4R)-2,2-dimethyl-4-(2-oxoethyl)-1,3-oxazolidine-3-carboxylate;tert-butyl (R)-2,2-dimethyl-4-(2-oxoethyl)oxazolidine-3-carboxylate;(R)-3-Boc-2,2-dimethyloxazolidine-4-acetaldehyde;(R)-Tert-butyl2,2-dimethyl-4-(2-oxoethyl)oxazolidine-3-carboxylate;SCHEMBL12516254;DTXSID00444788;GAWRNYMYEGSVFV-SECBINFHSA-N;AKOS015910719;CS-0447185;A927088;2,2-Dimethyl-3-(tert-butyloxycarbonyl)oxazolidine-4alpha-acetaldehyde;(4R)-2,2-DIMETHYL-4-(2-OXOETHYL)-OXAZOLIDINE-3-CARBOXYLIC ACID TERT-BUTYL ESTER

Suppliers and Price of (R)-Tert-butyl 2,2-dimethyl-4-(2-oxoethyl)oxazolidine-3-carboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
(R)-tert-Butyl2,2-dimethyl-4-(2-oxoethyl)oxazolidine-3-carboxylate 95+%
1g
$ 736.00

Crysdot
(R)-tert-Butyl2,2-dimethyl-4-(2-oxoethyl)oxazolidine-3-carboxylate 95+%
5g
$ 2578.00

Chemenu
tert-butyl(R)-2,2-dimethyl-4-(2-oxoethyl)oxazolidine-3-carboxylate 95%
5g
$ 2429.00

Chemenu
tert-butyl(R)-2,2-dimethyl-4-(2-oxoethyl)oxazolidine-3-carboxylate 95%
1g
$ 695.00

American Custom Chemicals Corporation
(R)-TERT-BUTYL-2,2-DIMETHYL-4-(2-OXOETHYL)OXAZOLIDINE-3-CARBOXYLATE 98.00%
0.25G
$ 383.00

AK Scientific
(R)-tert-Butyl2,2-dimethyl-4-(2-oxoethyl)oxazolidine-3-carboxylate
1g
$ 998.00

Activate Scientific
(R)-3-Boc-2,2-dimethyloxazolidine-4-acetaldehyde 95+% ee
1 g
$ 879.00

Total 9 raw suppliers

Chemical Property of (R)-Tert-butyl 2,2-dimethyl-4-(2-oxoethyl)oxazolidine-3-carboxylate

Chemical Property:

PSA：55.84000
LogP:1.88530
Storage Temp.:2-8°C
XLogP3:1
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:4
Exact Mass:243.14705815
Heavy Atom Count:17
Complexity:306

Purity/Quality:

97% ^*data from raw suppliers

(R)-tert-Butyl2,2-dimethyl-4-(2-oxoethyl)oxazolidine-3-carboxylate 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1(N(C(CO1)CC=O)C(=O)OC(C)(C)C)C
Isomeric SMILES:CC1(N([C@@H](CO1)CC=O)C(=O)OC(C)(C)C)C

Technology Process of (R)-Tert-butyl 2,2-dimethyl-4-(2-oxoethyl)oxazolidine-3-carboxylate

There total 9 articles about (R)-Tert-butyl 2,2-dimethyl-4-(2-oxoethyl)oxazolidine-3-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 201404-86-6
tert-butyl (4R)-4-(2-hydroxyethyl)-2,2-dimethyl-1,3-oxazolidine-3-carboxylate

: 153053-19-1
(4R)-2,2-dimethyl-4-(2-oxoethyl)-oxazolidine-3-carboxylic acid tert-butyl ester

Guidance literature:: With 1,3-oxazolidine; 1-hydroxy-3H-benz[d][1,2]iodoxole-1,3-dione; In ethyl acetate; at 80 ℃; for 3.5h;
DOI:10.1002/chem.201700604

Reference yield: 70.0%

: 857906-89-9
(4R)-4-cyanomethyl-2,2-dimethyl-oxazolidine-3-carboxylic acid tert-butyl ester

: 153053-19-1
(4R)-2,2-dimethyl-4-(2-oxoethyl)-oxazolidine-3-carboxylic acid tert-butyl ester

Guidance literature:: With diisobutylaluminium hydride; In hexane; dichloromethane; at -40 ℃; for 2h;
DOI:10.1081/SCC-200057988

Reference yield:

: 153053-18-0
C₁₃H₂₃NO₅

: 153053-19-1
(4R)-2,2-dimethyl-4-(2-oxoethyl)-oxazolidine-3-carboxylic acid tert-butyl ester

Guidance literature:: C₁₃H₂₃NO₅; With diisobutylaluminium hydride; In hexane; dichloromethane; at -90 - -85 ℃; for 0.75h; Inert atmosphere;

With methanol; In hexane; dichloromethane; at -85 ℃; Inert atmosphere;
DOI:10.1016/j.tetlet.2011.09.136