Pyrazolo[1,5-a]pyridine, 2-(1-methylethyl)- (9CI)

Base Information

Chemical Name:Pyrazolo[1,5-a]pyridine, 2-(1-methylethyl)- (9CI)
CAS No.:59942-84-6
Molecular Formula:C10H12N2
Molecular Weight:160.219
Hs Code.:
Mol file:59942-84-6.mol

Synonyms:Pyrazolo[1,5-a]pyridine, 2-(1-methylethyl)- (9CI)

Suppliers and Price of Pyrazolo[1,5-a]pyridine, 2-(1-methylethyl)- (9CI)

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
2-Isopropylpyrazolo[1,5-a]pyridine
1g
$ 485.00

AccelPharmtech
2-(1-methylethyl)-Pyrazolo[1,5-a]pyridine 97.00%
25G
$ 5120.00

AccelPharmtech
2-(1-methylethyl)-Pyrazolo[1,5-a]pyridine 97.00%
5G
$ 2750.00

AccelPharmtech
2-(1-methylethyl)-Pyrazolo[1,5-a]pyridine 97.00%
1G
$ 2370.00

Total 5 raw suppliers

Chemical Property of Pyrazolo[1,5-a]pyridine, 2-(1-methylethyl)- (9CI)

Chemical Property:

PSA：17.30000
LogP:2.45770
Storage Temp.:-20°C Freezer
Solubility.:Dichloromethane; Ethyl Acetate; Methanol

Purity/Quality:

97% ^*data from raw suppliers

2-Isopropylpyrazolo[1,5-a]pyridine ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Uses 2-Isopropylpyrazolo[1,5-a]pyridine is an intermediate in the synthesis of AV1013 (2-Amino-1-[2-(1-methylethyl) pyrazolo[1,5-a] pyridin-3-yl]-1-propanone hydrochloride) (A618170), which is a drug candidate for the treatment of neuropathic pain, addiction behavior and drug withdrwal symptoms.

Technology Process of Pyrazolo[1,5-a]pyridine, 2-(1-methylethyl)- (9CI)

There total 7 articles about Pyrazolo[1,5-a]pyridine, 2-(1-methylethyl)- (9CI) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

: 50847-11-5
ibudilast

: 59942-84-6
2-isopropyl-pyrazolo[1,5-a]pyridine

Guidance literature:: ibudilast; With sulfuric acid; In water; at 135 ℃; Inert atmosphere;

With sodium hydroxide; In water; at 25 ℃;

Reference yield: 96.0%

: 126959-38-4
(2-isopropyl-pyrazolo[1,5-a]pyridin-3-carboxylic acid)

: 59942-84-6
2-isopropyl-pyrazolo[1,5-a]pyridine

Guidance literature:: (2-isopropyl-pyrazolo[1,5-a]pyridin-3-carboxylic acid); With sulfuric acid; In water; at 135 ℃; Inert atmosphere;

With sodium hydroxide; In water; at 35 ℃;

Reference yield: 51.3%

: 7583-90-6
1-amino-2-methylpyridinium iodide

: 97-72-3
2-Methylpropionic anhydride

: 50847-11-5
ibudilast

: 59942-84-6
2-isopropyl-pyrazolo[1,5-a]pyridine

Guidance literature:: With potassium carbonate; In water; ethyl acetate; at 20 ℃; for 9h; Product distribution / selectivity; Heating / reflux;