NIPECOTIC ACID

Base Information

Chemical Name:NIPECOTIC ACID
CAS No.:60252-41-7
Molecular Formula:C₆H₁₁NO₂
Molecular Weight:129.159
Hs Code.:
Mol file:60252-41-7.mol

Synonyms:(R,S)-NIPECOTIC ACID;RARECHEM AK HD C011;RARECHEM AK PQ 0322;(+/-)-PIPERIDINE-3-CARBOXYLIC ACID;PIPERIDINE-3-CARBOXYLIC ACID;PIPERIDIN-3-CARBOXYLIC ACID;L-NIPECOTIC ACID;LABOTEST-BB LT00233199

Suppliers and Price of NIPECOTIC ACID

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
(±)-NipecoticAcid
25g
$ 65.00

TRC
(±)-NipecoticAcid
5g
$ 50.00

ApexBio Technology
(±)-Nipecoticacid
100mg
$ 128.00

Total 8 raw suppliers

Chemical Property of NIPECOTIC ACID

Chemical Property:

Melting Point:261 °C (dec.)(lit.)
PSA：49.33000
LogP:0.39940
Storage Temp.:Store at RT

Purity/Quality:

99% ^*data from raw suppliers

(±)-NipecoticAcid ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:Xi
Statements: 36/37/38
Safety Statements: 26-36

MSDS Files:: SDS file from LookChem

Useful:

Uses (±)-Nipecotic Acid is a novel transporter of GABA transporters GAT-2 and GAT-3.

Technology Process of NIPECOTIC ACID

There total 31 articles about NIPECOTIC ACID which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

: 498-96-4
guvacine

: 498-95-3,25137-00-2,59045-82-8,60252-41-7,262853-93-0
(R)-nipecotic acid

Guidance literature:: With C₆₃H₇₈IrNOP⁽²⁺⁾*C₃₂H₁₂BF₂₄^(1-); hydrogen; In methanol; at 60 ℃; for 12h; under 4560.31 Torr; enantioselective reaction; Autoclave;
DOI:10.1002/anie.201301341

Reference yield: 37.0%

: 88495-54-9
(3S)-1-(tert-butoxycarbonyl)piperidine-3-carboxylic acid

: 498-95-3,25137-00-2,59045-82-8,60252-41-7,262853-93-0
(S)-nipecotic acid

Guidance literature:: (3S)-1-(tert-butoxycarbonyl)piperidine-3-carboxylic acid; With methanesulfonic acid; In dichloromethane; at 25 ℃; for 16h;

With triethylamine; In dichloromethane; at 25 ℃; for 0.5h;