Chemical Property of Cyclohexyl biphenyl-3-ylcarbamate
Chemical Property:
- Appearance/Colour:off-white solid
- Vapor Pressure:0mmHg at 25°C
- Melting Point:122-123 °C
- Refractive Index:1.595
- Boiling Point:416.611 °C at 760 mmHg
- Flash Point:205.759 °C
- PSA：38.33000
- Density:1.149 g/cm3
- LogP:5.30780
- Storage Temp.:2-8°C
- Solubility.:DMSO: >10mg/mL
- XLogP3:4.9
- Hydrogen Bond Donor Count:1
- Hydrogen Bond Acceptor Count:2
- Rotatable Bond Count:4
- Exact Mass:295.157228913
- Heavy Atom Count:22
- Complexity:345
- Purity/Quality:
-
99%, *data from raw suppliers
URB602 *data from reagent suppliers
Safty Information:
- Pictogram(s):
- Hazard Codes:
- MSDS Files:
-
SDS file from LookChem
Useful:
- Canonical SMILES:C1CCC(CC1)OC(=O)NC2=CC=CC(=C2)C3=CC=CC=C3
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Uses
URB602 is a selective inhibitor of MGL, exhibiting an IC50 of 28 for the rat brain enzyme. It does not inhibit fatty acid amide hydrolase (FAAH) at concentrations up to 100 , or other lipid metabolizing enzymes such as diacylglycerol lipase or URB602 is a selective inhibitor of MGL, exhibiting an IC50 of 28 μM for the rat brain enzyme. It does not inhibit fatty acid amide hydrolase (FAAH) at concentrations up to 100 μM, or other lipid metabolizing enzymes such as diacylglycerol lipase or cyclooxygenase-2.5 6 Inhibition of 2-AG hydrolysis is associated with enhanced stress-induced analgesia and may represent a novel drug target in pain and stress management.
