1,3-Bis(di(orthomethoxyphenyl)phosphino)propane

Base Information

• Chemical Name: 1,3-Bis(di(orthomethoxyphenyl)phosphino)propane
• CAS No.: 116163-96-3
• Molecular Formula: C31H34 O4 P2
• Molecular Weight: 532.556
• European Community (EC) Number: 413-430-2,682-091-2
• UNII: 3A375A6NYT
• DSSTox Substance ID: DTXSID7073806
• Nikkaji Number: J1.057.608C
• Wikidata: Q27256946
• Mol file: 116163-96-3.mol

Synonyms:116163-96-3;1,3-Bis(di(orthomethoxyphenyl)phosphino)propane;3-bis(2-methoxyphenyl)phosphanylpropyl-bis(2-methoxyphenyl)phosphane;1,3-Bis(bis(2-methoxyphenyl)phosphino)propane;UNII-3A375A6NYT;3A375A6NYT;1,3-Bis[bis(2-methoxyphenyl)phosphino]propane;Phosphine, 1,3-propanediylbis[bis(2-methoxyphenyl)-;EC 413-430-2;Phosphine, 1,3-propanediylbis(bis(2-methoxyphenyl)-;P,P,P',P'-tetrakis-(o-methoxyphenyl)propane-1,3-diphosphine;Phosphine, 1,1'-(1,3-propanediyl)bis[1,1-bis(2-methoxyphenyl)-;PHOSPHINE, 1,1'-(1,3-PROPANEDIYL)BIS(1,1-BIS(2-METHOXYPHENYL)-;SCHEMBL2332056;DTXSID7073806;MFCD11520103;1,3-bis(di(2-methoxyphenyl)phosphino)propane;1,3-Bis[bis-(o-methoxyphenyl)phosphino]propane;1,3-bis(bis(2-methoxyphenyl)phosphi no)propane;1,3-bis[bis-(2-Methoxyphenyl)phosphino]propane;1,3-BIS(BIS(O-METHOXYPHENYL)PHOSPHINO)PROPANE;Q27256946;TRIMETHYLENEBIS(BIS(2-METHOXYPHENYL)PHOSPHINE)

Chemical Property of 1,3-Bis(di(orthomethoxyphenyl)phosphino)propane

Chemical Property:

• Melting Point: 220℃
• Boiling Point: 647.3°Cat760mmHg
• Flash Point: 435.5°C
• PSA: 64.10000
• Density: g/cm³
• LogP: 5.67670
• XLogP3: 6.1
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 12
• Exact Mass: 532.19323356
• Heavy Atom Count: 37
• Complexity: 536

Purity/Quality:

99.9% ^*data from raw suppliers

Safty Information:

• Hazard Codes: N
• Statements: 50/53
• Safety Statements: 60-61

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: COC1=CC=CC=C1P(CCCP(C2=CC=CC=C2OC)C3=CC=CC=C3OC)C4=CC=CC=C4OC
• Use Description: P,P,P',P'-tetrakis-(o-methoxyphenyl)propane-1,3-diphosphine is a chemical compound with applications across different fields. In the field of organometallic chemistry and catalysis, it serves as a ligand or coordinating agent, facilitating various transition metal-catalyzed reactions. Its role is crucial in promoting catalytic efficiency and selectivity, making it valuable in the synthesis of fine chemicals, pharmaceuticals, and specialty materials. Additionally, in the realm of materials science and nanotechnology, this compound can be employed as a stabilizing ligand in the synthesis of nanoparticles, quantum dots, and nanomaterials, influencing their size, shape, and properties for applications in electronics, sensors, and materials with tailored characteristics. Its versatility as a catalytic ligand and nanomaterial stabilizer underscores its significance in advancing catalysis, materials science, and nanotechnology in various fields.

Technology Process of 1,3-Bis(di(orthomethoxyphenyl)phosphino)propane

There total 5 articles about 1,3-Bis(di(orthomethoxyphenyl)phosphino)propane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.3%

1,3-bis[bis(2-methoxyphenyl)phosphono]propane (1370406-93-1) → 1,3-bis[di(2-methoxyphenyl)-phosphino]propane (116163-96-3)

Guidance literature:

With tributyl-amine; trichlorosilane; In toluene; at 5 ℃; Solvent; Temperature; Reagent/catalyst; Reflux;

Reference yield:

Bisphosphine oxide (71360-04-8) → 1,3-bis[di(2-methoxyphenyl)-phosphino]propane (116163-96-3)

Guidance literature:

Multi-step reaction with 2 steps

1: tetra-(n-butyl)ammonium iodide; potassium hydroxide / water; benzene / 7 h / 20 - 80 °C / Inert atmosphere

2: tributyl-amine; trichlorosilane / acetonitrile / 5 h / 70 °C / Inert atmosphere

With tributyl-amine; trichlorosilane; tetra-(n-butyl)ammonium iodide; potassium hydroxide; In water; acetonitrile; benzene;

DOI:10.1021/ja302177z

Reference yield:

bis(2-methoxyphenyl)phosphine (10177-79-4) + 1,3-Dichloropropane (142-28-9) → 1,3-bis[di(2-methoxyphenyl)-phosphino]propane (116163-96-3)

Guidance literature:

With sodium; In water; dimethyl sulfoxide;

upstream raw materials:

bis(2-methoxyphenyl)phosphine

1,3-Dichloropropane

1,3-bis[bis(2-methoxyphenyl)phosphono]propane

Bisphosphine oxide

Downstream raw materials:

(1,3-propanediyl)bis<(2-methoxyphenyl)phosphine>

dichloro(1,3-bis(di(2-methoxyphenyl)phosphino)propane)palaldium(II)

[Ni(1,3-bis[di(o-methoxyphenyl)phosphanyl]propane)Cl₂]

1,3-bis(di(ortho-methoxyphenyl)phosphanyl)propane nickel(II) di(trifluoroacetate)