Technology Process of Imidazo[1,5-a]pyridine-8-carboxylic acid (9CI)
There total 1 articles about Imidazo[1,5-a]pyridine-8-carboxylic acid (9CI) which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
With
potassium hydroxide;
In
methanol;
for 0.5h;
Heating / reflux;
- Guidance literature:
-
Multi-step reaction with 2 steps
1: triethylamine; N-[(dimethylamino)-3-oxo-1H-1,2,3-triazolo[4,5-b]pyridin-1-yl-methylene]-N-methylmethanaminium hexafluorophosphate / N,N-dimethyl-formamide / 2 h / 20 °C / Inert atmosphere
2: lithium aluminium tetrahydride / tetrahydrofuran / 0.5 h / 20 °C / Inert atmosphere
With
lithium aluminium tetrahydride; triethylamine; N-[(dimethylamino)-3-oxo-1H-1,2,3-triazolo[4,5-b]pyridin-1-yl-methylene]-N-methylmethanaminium hexafluorophosphate;
In
tetrahydrofuran; N,N-dimethyl-formamide;
- Guidance literature:
-
Multi-step reaction with 5 steps
1: triethylamine; N-[(dimethylamino)-3-oxo-1H-1,2,3-triazolo[4,5-b]pyridin-1-yl-methylene]-N-methylmethanaminium hexafluorophosphate / N,N-dimethyl-formamide / 2 h / 20 °C / Inert atmosphere
2: lithium aluminium tetrahydride / tetrahydrofuran / 0.5 h / 20 °C / Inert atmosphere
3: tetrahydrofuran / 1 h / 20 °C / Inert atmosphere
4: Dess-Martin periodane / dichloromethane / 3 h / 20 °C / Inert atmosphere
5: tetrahydrofuran / 1 h / 20 °C / Inert atmosphere
With
lithium aluminium tetrahydride; Dess-Martin periodane; triethylamine; N-[(dimethylamino)-3-oxo-1H-1,2,3-triazolo[4,5-b]pyridin-1-yl-methylene]-N-methylmethanaminium hexafluorophosphate;
In
tetrahydrofuran; dichloromethane; N,N-dimethyl-formamide;
