N N-BIS-[(R)-1-PHENYLETHYL]DIBENZO[D F][

Base Information

• Chemical Name: N N-BIS-[(R)-1-PHENYLETHYL]DIBENZO[D F][
• CAS No.: 500103-26-4
• Molecular Formula: C28H26NO2P
• Molecular Weight: 439.494
• Hs Code.: 2921499090
• Mol file: 500103-26-4.mol

Synonyms:N N-BIS-[(R)-1-PHENYLETHYL]DIBENZO[D F][;BIPOL-A1(R), (R,R)-N-(5,7-Diox-6-phosphadibenzo[a,c]cyclohepten-6-yl)bis(1-phenylethyl)amine, O,Oμ-(2,2μ-Biphenyldiyl) N,N-bis[(R)-1-phenylethyl]phosphoramidite

Chemical Property of N N-BIS-[(R)-1-PHENYLETHYL]DIBENZO[D F][

Chemical Property:

• Vapor Pressure: 2.24E-13mmHg at 25°C
• Melting Point: 99-102 °C
• Boiling Point: 578.4°C at 760 mmHg
• PKA: -0.31±0.20(Predicted)
• Flash Point: 303.6°C
• PSA: 35.29000
• LogP: 8.17610
• Sensitive.: moisture sensitive

Purity/Quality:

98%,99%, ^*data from raw suppliers

N,N-Bis[(1R)-(+)-phenylethyl]dibenzo[d,f][1,3,2]dioxaphosphepin-6-amine ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: N,N-Bis-[(R)-1-phenylethyl]dibenzo[d,f][1,3,2]dioxaphosphepin-6-amine can be used:In the asymmetric hydrovinylation of 1,3-diene.In the 1,4-asymmetric conjugate addition of 3-substituted cyclohexenones catalyzed by copper.

Technology Process of N N-BIS-[(R)-1-PHENYLETHYL]DIBENZO[D F][

There total 4 articles about N N-BIS-[(R)-1-PHENYLETHYL]DIBENZO[D F][ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

6-chloro-dibenzo[d,f][1,3,2]-dioxaphosphepin (16611-68-0) + (R,R)-N,N-bis-(1-phenylethyl)amine (10024-74-5,21003-56-5,21003-57-6,23294-41-9,42287-48-9,56210-72-1) → O,O'-(1,1'-biphenyl-2,2'-diyl)-N,N'-bis[(S,S)-1-phenyl-ethyl]phosphoramidite (500103-26-4)

Guidance literature:

In tetrahydrofuran;

DOI:10.1055/s-0029-1216826

Reference yield:

2,2'-dihydroxybiphenyl (1806-29-7) + (R,R)-N,N-bis-(1-phenylethyl)amine (10024-74-5,21003-56-5,21003-57-6,23294-41-9,42287-48-9,56210-72-1) → O,O'-(1,1'-biphenyl-2,2'-diyl)-N,N'-bis[(S,S)-1-phenyl-ethyl]phosphoramidite (500103-26-4)

Guidance literature:

(R,R)-N,N-bis-(1-phenylethyl)amine; With triethylamine; phosphorus trichloride; In toluene; at 70 ℃; for 6h;

2,2'-dihydroxybiphenyl; With triethylamine; In toluene; at -78 - 20 ℃;

DOI:10.1021/ol0524095

Reference yield:

2,2'-dihydroxybiphenyl (1806-29-7) + [(R,R)-bis(α-methylbenzyl)amino]phosphorous dichloride (777067-26-2) → O,O'-(1,1'-biphenyl-2,2'-diyl)-N,N'-bis[(S,S)-1-phenyl-ethyl]phosphoramidite (500103-26-4)

Guidance literature:

With triethylamine; In tetrahydrofuran; toluene; at -78 - 25 ℃;

DOI:10.1002/chem.200500464

upstream raw materials:

2,2'-dihydroxybiphenyl

(R,R)-N,N-bis-(1-phenylethyl)amine

[(R,R)-bis(α-methylbenzyl)amino]phosphorous dichloride

6-chloro-dibenzo[d,f][1,3,2]-dioxaphosphepin