3-hydrazino-5-methyl-4H-1,2,4-triazol-4-ylamine hydrochloride

Base Information

• Chemical Name: 3-hydrazino-5-methyl-4H-1,2,4-triazol-4-ylamine hydrochloride
• CAS No.: 59545-76-5
• Molecular Formula: C3H8N6
• Molecular Weight: 164.6
• Hs Code.: 2933990090
• DSSTox Substance ID: DTXSID80597468
• Mol file: 59545-76-5.mol

Synonyms:59545-76-5;3-hydrazino-5-methyl-4H-1,2,4-triazol-4-ylamine hydrochloride;873-28-9;3-hydrazinyl-5-methyl-4H-1,2,4-triazol-4-amine hydrochloride;3-hydrazinyl-5-methyl-1,2,4-triazol-4-amine;hydrochloride;SCHEMBL9420585;3-hydrazinyl-5-methyl-1,2,4-triazol-4-amine hydrochloride;DTXSID80597468;CFGXZSUQSDATNR-UHFFFAOYSA-N;MFCD00205268;AKOS005071427;9G-008;J-512603;4-amino-3-hydrazino-5-methyl-1,2,4-triazole hydrochloride;3-hydrazinyl-5-methyl-4H-1,2,4-triazol-4-aminehydrochloride;3-Hydrazinyl-5-methyl-4H-1,2,4-triazol-4-amine--hydrogen chloride (1/1)

Chemical Property of 3-hydrazino-5-methyl-4H-1,2,4-triazol-4-ylamine hydrochloride

Chemical Property:

• Vapor Pressure: 8.63E-07mmHg at 25°C
• Melting Point: 217-218°
• Boiling Point: 400°C at 760 mmHg
• Flash Point: 195.7°C
• PSA: 94.78000
• LogP: 0.74240
• Hydrogen Bond Donor Count: 4
• Hydrogen Bond Acceptor Count: 5
• Rotatable Bond Count: 1
• Exact Mass: 164.0577220
• Heavy Atom Count: 10
• Complexity: 94.3

Purity/Quality:

98% ^*data from raw suppliers

3-hydrazino-5-methyl-4H-1,2,4-triazol-4-aminedihydrochloride ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC1=NN=C(N1N)NN.Cl

Technology Process of 3-hydrazino-5-methyl-4H-1,2,4-triazol-4-ylamine hydrochloride

There total 4 articles about 3-hydrazino-5-methyl-4H-1,2,4-triazol-4-ylamine hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 77.0%

3-methyl-4-amino-5-mercapto-1,2,4-triazole (20939-15-5) → 3-hydrazino-5-methyl-[1,2,4]triazol-4-ylamine (59545-76-5)

Guidance literature:

With hydrazine hydrate; In ethanol; Reflux;

DOI:10.1007/s10847-010-9794-4

Reference yield:

triaminoguanidine hydrochloride + acetic acid (64-19-7,77671-22-8) → 3-hydrazino-5-methyl-[1,2,4]triazol-4-ylamine (59545-76-5)

Guidance literature:

With hydrogenchloride; for 2h; Reflux;

DOI:10.1055/s-0036-1591764

Reference yield:

4-amino-5-methyl-2,4-dihydro-[1,2,4]triazole-3-thione (20939-15-5,121761-38-4) → 3-hydrazino-5-methyl-[1,2,4]triazol-4-ylamine (59545-76-5)

Guidance literature:

With hydrazine;

DOI:10.1016/j.molstruc.2017.04.118

upstream raw materials:

3-methyl-4-amino-5-mercapto-1,2,4-triazole

4-amino-5-methyl-2,4-dihydro-[1,2,4]triazole-3-thione

acetic acid