1(2H)-Naphthalenone,3,4-dihydro-3-(hydroxymethyl)-,(3R)-(9CI)

Base Information

Chemical Name:1(2H)-Naphthalenone,3,4-dihydro-3-(hydroxymethyl)-,(3R)-(9CI)
CAS No.:534599-18-3
Molecular Formula:C₁₁H₁₂O₂
Molecular Weight:176.215
Hs Code.:
Mol file:534599-18-3.mol

Synonyms:1(2H)-Naphthalenone,3,4-dihydro-3-(hydroxymethyl)-,(3R)-(9CI)

Suppliers and Price of 1(2H)-Naphthalenone,3,4-dihydro-3-(hydroxymethyl)-,(3R)-(9CI)

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Total 1 raw suppliers

Chemical Property of 1(2H)-Naphthalenone,3,4-dihydro-3-(hydroxymethyl)-,(3R)-(9CI)

Chemical Property:

PSA：37.30000
LogP:1.42400

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 1(2H)-Naphthalenone,3,4-dihydro-3-(hydroxymethyl)-,(3R)-(9CI)

There total 18 articles about 1(2H)-Naphthalenone,3,4-dihydro-3-(hydroxymethyl)-,(3R)-(9CI) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

: 534599-16-1
(1R,3R)-3-(hydroxymethyl)-1,2,3,4-tetrahydronaphthalen-1-ol

: 534599-18-3
(R)-(-)-3-hydroxymethyl-1,2,3,4-tetrahydronaphthalen-1-one

Guidance literature:: With manganese(IV) oxide; In chloroform; at 20 ℃; for 4h;
DOI:10.1016/j.tetasy.2003.08.016

Reference yield: 40.0%

: 22818-49-1,91970-18-2
(+/-)-cis-3-(hydroxymethyl)-1,2,3,4-tetrahydronaphthalen-1-ol

: 534599-17-2
(S)-(+)-3-hydroxymethyl-1,2,3,4-tetrahydronaphthalen-1-one

: 534599-18-3
(R)-(-)-3-hydroxymethyl-1,2,3,4-tetrahydronaphthalen-1-one

: 534599-16-1
(1R,3R)-3-(hydroxymethyl)-1,2,3,4-tetrahydronaphthalen-1-ol

Guidance literature:: Ru(II)-(1S,2S)-N-p-toluenesulfonyl-1,2-di-Ph-ethylenediamine; In acetone; at 28 ℃; for 36h;
DOI:10.1016/j.tetasy.2003.08.016

Reference yield:

: 55571-74-9
methyl 1,2,3,4-tetrahydro-4-oxo-naphthalene-2-carboxylate

: 534599-18-3
(R)-(-)-3-hydroxymethyl-1,2,3,4-tetrahydronaphthalen-1-one

Guidance literature:: Multi-step reaction with 3 steps

1: 85 percent / LiAlH₄ / tetrahydrofuran / 12 h / 20 °C

2: Ru(II)-(S,S)-N-tosyl-1,2-diphenylethane-1,2-diamine / acetone / 28 h / 28 °C

3: 75 percent / MnO₂ / CHCl₃ / 4 h / 20 °C

With manganese(IV) oxide; lithium aluminium tetrahydride; Ru(II)-(1S,2S)-N-p-toluenesulfonyl-1,2-di-Ph-ethylenediamine; In tetrahydrofuran; chloroform; acetone;
DOI:10.1016/j.tetasy.2003.08.016