534599-17-2

Usage

Uses

Used in Pharmaceutical Industry:
1(2H)-Naphthalenone,3,4-dihydro-3-(hydroxymethyl)-,(3S)-(9CI) is used as an intermediate compound for the synthesis of various pharmaceutical products. Its unique structure and functional groups make it a valuable building block in the development of new drugs with potential therapeutic applications.
Used in Agrochemical Industry:
In the agrochemical industry, 1(2H)-Naphthalenone,3,4-dihydro-3-(hydroxymethyl)-,(3S)-(9CI) is used as a starting material for the creation of novel agrochemicals. Its structural properties allow for the development of compounds with specific pesticidal, herbicidal, or fungicidal activities, contributing to more effective and targeted crop protection.
Used in Organic Synthesis:
1(2H)-Naphthalenone,3,4-dihydro-3-(hydroxymethyl)-,(3S)-(9CI) serves as a key intermediate in organic synthesis, particularly for the production of complex organic molecules with diverse applications. Its unique structure and reactivity enable the synthesis of a wide range of compounds, from specialty chemicals to advanced materials.

Upstream product

• 108-05-4 vinyl acetate 
• 88165-86-0 3-hydroxymethyl-1,2,3,4-tetrahydronaphthalen-1-one 
• 22818-49-1 (+/-)-cis-3-(hydroxymethyl)-1,2,3,4-tetrahydronaphthalen-1-ol 

Downstream Products

• 534599-19-4 (S)-4-oxo-1,2,3,4-tetrahydronaphthalen-2-ylmetyl 4-methylbenzenesulfonate 

Relevant academic research and scientific papers

Chemoenzymatic synthesis and binding affinity of novel (R)- and (S)-3-aminomethyl-1-tetralones, potential atypical antipsychotics

A series of (R)- and (S)-3-aminomethyl-1-tetralones, conformationally constrained analogues of haloperidol, have been obtained by enzymatic resolution of the corresponding racemic 3-hydroxymethyl-1-tetralones using Pseudomonas fluorescens lipase. Their bi

Kinetic resolution of 3-hydroxymethylbenzocycloalkanols by selective asymmetric hydrogen-transfer oxidation

Kinetic resolution of 3-hydroxymethylbenzocycloalkanols was performed by selective asymmetric hydrogen-transfer oxidation using the Ru(II)-(S,S)-TsDPEN catalyst. Thus, several 3-hydroxymethyl-1-tetralols 7a-d afforded (1R,3R)-3-hydroxymethyl-1-tetralols (

Preparation of (R)-(-)- and (S)-(+)-3-hydroxymethyl-1-tetralone tosylates, key intermediates in the synthesis of new CNS drugs, via resolution of precursors

The preparation of (R)-(-)- and (S)-(+)-3-hydroxymethyl-1-tetralone tosylates, key intermediates in the synthesis of new CNS drugs in the aminobutyrophenone family, has been developed via classical resolutions or lipase-catalyzed kinetic resolution of one of their precursors.